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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

Clinical cancer research, 2014-05, Vol.20 (10), p.2651-2662

2014

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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.1029-1040

2011

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Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

The Lancet (British edition), 2004-04, Vol.363 (9418), p.1346-1353

2004

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Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling

The Journal of biological chemistry, 2011-10, Vol.286 (40), p.34712-34721

2011

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High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

Clinical cancer research, 2011-04, Vol.17 (8), p.2314-2327

2011

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The Reciprocal Regulation of γ-Synuclein and IGF-I Receptor Expression Creates a Circuit That Modulates IGF-I Signaling

The Journal of biological chemistry, 2010-10, Vol.285 (40), p.30480-30488

2010

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Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

Diabetes (New York, N.Y.), 2023-10, Vol.72 (10), p.1460-1469

2023

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Regulation of muscle mass by growth hormone and IGF‐I

British journal of pharmacology, 2008-06, Vol.154 (3), p.557-568

Velloso, C P

2008

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Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling

The Journal of biological chemistry, 2010-03, Vol.285 (12), p.8743-8758

2010

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Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The FASEB journal, 2014-03, Vol.28 (3), p.1294-1305

2014

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Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

The Journal of biological chemistry, 2014-02, Vol.289 (8), p.4626-4633

2014

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IGF‐I protects porcine granulosa cells from hypoxia‐induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

The FASEB journal, 2024-01, Vol.38 (1), p.e23332-n/a

2024

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Effect of IGF‐I in the Chondrogenesis of Bone Marrow Mesenchymal Stem Cells in the Presence or Absence of TGF‐β Signaling

Journal of bone and mineral research, 2006-04, Vol.21 (4), p.626-636

2006

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Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women

European journal of endocrinology, 2004-02, Vol.150 (2), p.161-171

2004

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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nature medicine, 2012-11, Vol.18 (11), p.1643-1650

2012

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Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Diabetes (New York, N.Y.), 2017-01, Vol.66 (1), p.64-74

2017

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Growth hormone, IGF‐I and insulin and their abuse in sport

British journal of pharmacology, 2008-06, Vol.154 (3), p.542-556

2008

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IGF-II is regulated by microRNA-125b in skeletal myogenesis

The Journal of cell biology, 2011-01, Vol.192 (1), p.69-81

2011

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IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development

Development (Cambridge), 2011-05, Vol.138 (9), p.1795-1805

2011

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IGF-Binding Proteins and Their Proteolysis as a Mechanism of Regulated IGF Release in the Nervous Tissue

Biochemistry (Moscow), 2023, Vol.88 (Suppl 1), p.S105-S122

2023

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Aging Impairs IGF‐I Receptor Activation and Induces Skeletal Resistance to IGF‐I

Journal of bone and mineral research, 2007-08, Vol.22 (8), p.1271-1279

2007

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PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling

Journal of bone and mineral research, 2015-11, Vol.30 (11), p.1959-1968

2015

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The effects of protein supplementation of fall calving beef cows on pre- and postpartum plasma insulin, glucose and IGF-I, and postnatal growth and plasma insulin and IGF-I of calves

Journal of animal science, 2018-07, Vol.96 (7), p.2629-2639

2018

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Dose–exposure–IGF-I response of once-weekly somapacitan in adults with GH deficiency

European journal of endocrinology, 2022-07, Vol.187 (1), p.27-38

2022

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Insulin and Insulin-like Growth Factor-I (IGF-I) Receptor Overexpression in Breast Cancers Leads to Insulin/IGF-I Hybrid Receptor Overexpression: Evidence for a Second Mechanism of IGF-I Signaling

Clinical cancer research, 1999-07, Vol.5 (7), p.1935-1944

1999

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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling

High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

The Reciprocal Regulation of γ-Synuclein and IGF-I Receptor Expression Creates a Circuit That Modulates IGF-I Signaling

Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

Regulation of muscle mass by growth hormone and IGF‐I

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

IGF‐I protects porcine granulosa cells from hypoxia‐induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

Effect of IGF‐I in the Chondrogenesis of Bone Marrow Mesenchymal Stem Cells in the Presence or Absence of TGF‐β Signaling

Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Growth hormone, IGF‐I and insulin and their abuse in sport

IGF-II is regulated by microRNA-125b in skeletal myogenesis

IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development

IGF-Binding Proteins and Their Proteolysis as a Mechanism of Regulated IGF Release in the Nervous Tissue

Aging Impairs IGF‐I Receptor Activation and Induces Skeletal Resistance to IGF‐I

PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling

The effects of protein supplementation of fall calving beef cows on pre- and postpartum plasma insulin, glucose and IGF-I, and postnatal growth and plasma insulin and IGF-I of calves

Dose–exposure–IGF-I response of once-weekly somapacitan in adults with GH deficiency

Insulin and Insulin-like Growth Factor-I (IGF-I) Receptor Overexpression in Breast Cancers Leads to Insulin/IGF-I Hybrid Receptor Overexpression: Evidence for a Second Mechanism of IGF-I Signaling

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