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Comparative proteolytic processing of rat prosomatostatin by the convertases PC1, PC2, furin, PACE4 and PC5 in constitutive and regulated secretory pathways

FEBS letters, 1995-04, Vol.362 (2), p.143-146

1995

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Identification of glutamic acid 646 as a zinc-coordinating residue in endopeptidase-24.11

The Journal of biological chemistry, 1991-08, Vol.266 (24), p.15670-15674

1991

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Processing of Human Prosomatostatin in AtT-20 Cells: S-28 and S-14 Are Generated in Different Secretory Pathways

Biochemical and biophysical research communications, 1994-11, Vol.205 (1), p.221-229

1994

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Expression of neutral endopeptidase (enkephalinase) in heterologous COS-1 cells. Characterization of the recombinant enzyme and evidence for a glutamic acid residue at the active site

The Journal of biological chemistry, 1988-03, Vol.263 (8), p.4033-4040

1988

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A cleavable N-terminal signal peptide is not a prerequisite for the biosynthesis of glycosylphosphatidylinositol-anchored proteins

The Journal of biological chemistry, 1994-06, Vol.269 (25), p.16993-16996

1994

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Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells

The Journal of biological chemistry, 1989-09, Vol.264 (26), p.15620-15623

1989

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Expression and polarized apical secretion in Madin-Darby canine kidney cells of a recombinant soluble form of neutral endopeptidase lacking the cytosolic and transmembrane domains

The Journal of biological chemistry, 1992-02, Vol.267 (4), p.2798-2801

1992

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Transformation of the signal peptide/membrane anchor domain of a type II transmembrane protein into a cleavable signal peptide

The Journal of biological chemistry, 1993-02, Vol.268 (4), p.2699-2704

1993

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Neutral endopeptidase, a major brush border protein of the kidney proximal nephron, is directly targeted to the apical domain when expressed in Madin-Darby canine kidney cells

The Journal of biological chemistry, 1991-10, Vol.266 (29), p.19826-19832

1991

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Reduced Fertility in Male Mice Deficient in the Zinc Metallopeptidase NL1

Molecular and Cellular Biology, 2004-05, Vol.24 (10), p.4428-4437

2004

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Evidence that both arginine 102 and arginine 747 are involved in substrate binding to neutral endopeptidase (EC 3.4.24.11)

The Journal of biological chemistry, 1991-01, Vol.266 (1), p.214-220

1991

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Proteolytic processing of the alpha-subunit of rat endopeptidase-24.18 by furin

Biochemical journal, 1995-07, Vol.309 ( Pt 2) (2), p.683-688

1995

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Endothelin-converting enzyme-like 1 (ECEL1) is present both in the plasma membrane and in the endoplasmic reticulum

Biochemical journal, 2004-06, Vol.380 (Pt 3), p.881-888

2004

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Site‐specific mutagenesis identifies amino acid residues critical in prohormone processing

The EMBO journal, 1989-10, Vol.8 (10), p.2911-2916

1989

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Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family

Biochemical journal, 2000-04, Vol.347 (Pt 2), p.419-429

2000

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Disease-causing missense mutations in the PHEX gene interfere with membrane targeting of the recombinant protein

Human molecular genetics, 2001-07, Vol.10 (15), p.1539-1546

2001

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The nature of topogenic sequences determines the transport competence of topological mutants of neutral endopeptidase-24.11

Biochemical journal, 1995-11, Vol.312 ( Pt 1) (1), p.99-105

1995

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Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates

Biochemical journal, 2005-01, Vol.385 (Pt 2), p.389-397

2005

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Mechanism of Kex2p inhibition by its proregion

FEBS letters, 2001-11, Vol.508 (3), p.332-336

2001

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Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin

Biochemical journal, 2004-06, Vol.380 (Pt 2), p.441-448

2004

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Secretion of functional soluble form of neutral endopeptidase-24.11 from a baculovirus-infected insect cell line

Biochemical journal, 1992-05, Vol.284 (1), p.53-59

1992

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Recombinant human endothelin-converting enzyme ECE-1b is located in an intracellular compartment when expressed in polarized Madin-Darby canine kidney cells

Biochemical journal, 1998-07, Vol.333 ( Pt 2) (2), p.439-448

1998

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Neutral endopeptidase (EC 3.4.24.11): constructed molecular forms show new angles of an old enzyme

Biochemistry and cell biology, 1994-03, Vol.72 (3-4), p.67

1994

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Insertion of Hydrophilic Amino Acid Residues in the Signal Peptide/Membrane Anchor Domain of Neprilysin (Neutral Endopeptidase-24,11) Results in Its Cleavage: Role of the Position of Insertion

Archives of biochemistry and biophysics, 1994-12, Vol.315 (2), p.382-386

1994

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Charge polarity reversal inverses the specificity of neutral endopeptidase-24.11

The Journal of biological chemistry, 1992-02, Vol.267 (4), p.2138-2141

1992

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Comparative proteolytic processing of rat prosomatostatin by the convertases PC1, PC2, furin, PACE4 and PC5 in constitutive and regulated secretory pathways

Identification of glutamic acid 646 as a zinc-coordinating residue in endopeptidase-24.11

Processing of Human Prosomatostatin in AtT-20 Cells: S-28 and S-14 Are Generated in Different Secretory Pathways

Expression of neutral endopeptidase (enkephalinase) in heterologous COS-1 cells. Characterization of the recombinant enzyme and evidence for a glutamic acid residue at the active site

A cleavable N-terminal signal peptide is not a prerequisite for the biosynthesis of glycosylphosphatidylinositol-anchored proteins

Fusion of a cleavable signal peptide to the ectodomain of neutral endopeptidase (EC 3.4.24.11) results in the secretion of an active enzyme in COS-1 cells

Expression and polarized apical secretion in Madin-Darby canine kidney cells of a recombinant soluble form of neutral endopeptidase lacking the cytosolic and transmembrane domains

Transformation of the signal peptide/membrane anchor domain of a type II transmembrane protein into a cleavable signal peptide

Neutral endopeptidase, a major brush border protein of the kidney proximal nephron, is directly targeted to the apical domain when expressed in Madin-Darby canine kidney cells

Reduced Fertility in Male Mice Deficient in the Zinc Metallopeptidase NL1

Evidence that both arginine 102 and arginine 747 are involved in substrate binding to neutral endopeptidase (EC 3.4.24.11)

Proteolytic processing of the alpha-subunit of rat endopeptidase-24.18 by furin

Endothelin-converting enzyme-like 1 (ECEL1) is present both in the plasma membrane and in the endoplasmic reticulum

Site‐specific mutagenesis identifies amino acid residues critical in prohormone processing

Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family

Disease-causing missense mutations in the PHEX gene interfere with membrane targeting of the recombinant protein

The nature of topogenic sequences determines the transport competence of topological mutants of neutral endopeptidase-24.11

Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates

Mechanism of Kex2p inhibition by its proregion

Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin

Secretion of functional soluble form of neutral endopeptidase-24.11 from a baculovirus-infected insect cell line

Recombinant human endothelin-converting enzyme ECE-1b is located in an intracellular compartment when expressed in polarized Madin-Darby canine kidney cells

Neutral endopeptidase (EC 3.4.24.11): constructed molecular forms show new angles of an old enzyme

Insertion of Hydrophilic Amino Acid Residues in the Signal Peptide/Membrane Anchor Domain of Neprilysin (Neutral Endopeptidase-24,11) Results in Its Cleavage: Role of the Position of Insertion

Charge polarity reversal inverses the specificity of neutral endopeptidase-24.11

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