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Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes

Journal of neurology, neurosurgery and psychiatry, 2020-04, Vol.91 (4), p.350-358

2020

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Label-Free LC–MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis

Journal of proteome research, 2015-11, Vol.14 (11), p.4486-4501

2015

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Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide

Nature medicine, 2022-01, Vol.28 (1), p.117-124

2022

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Reactive astrocytes secrete lcn2 to promote neuron death

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.4069-4074

2013

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Neurofilaments in pre-symptomatic ALS and the impact of genotype

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2019-10, Vol.20 (7-8), p.538-548

2019

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Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue

PloS one, 2010-10, Vol.5 (10), p.e13250-e13250

2010

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Molecular subtypes of ALS are associated with differences in patient prognosis

Nature communications, 2023-01, Vol.14 (1), p.95-95, Article 95

2023

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Tocilizumab is safe and tolerable and reduces C‐reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients

Muscle & nerve, 2021-09, Vol.64 (3), p.309-320

2021

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Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD

Nature communications, 2022-05, Vol.13 (1), p.2799-2799, Article 2799

2022

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Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations

Nature reviews. Neurology, 2011-11, Vol.7 (11), p.631-638

2011

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Total protein is an effective loading control for cerebrospinal fluid western blots

Journal of neuroscience methods, 2015-08, Vol.251, p.72-82

2015

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Expression of Carbonic Anhydrase I in Motor Neurons and Alterations in ALS

International journal of molecular sciences, 2016-11, Vol.17 (11), p.1820-1820

2016

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Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

eLife, 2019-06, Vol.8

2019

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Transgenic rat model of neurodegeneration caused by mutation in the TDP gene

PLoS genetics, 2010-03, Vol.6 (3), p.e1000887-e1000887

2010

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SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy

JAMA neurology, 2013-02, Vol.70 (2), p.201

2013

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Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis

PloS one, 2010-12, Vol.5 (12), p.e15133-e15133

2010

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Optical barcoding of PLGA for multispectral analysis of nanoparticle fate in vivo

Journal of controlled release, 2017-05, Vol.253, p.172-182

2017

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The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease

Neurobiology of disease, 2021-02, Vol.149, p.105228-105228, Article 105228

2021

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Longitudinal biomarkers in amyotrophic lateral sclerosis

Annals of clinical and translational neurology, 2020-07, Vol.7 (7), p.1103-1116

2020

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Altered subcellular distribution of c-Abl in Alzheimer's disease

Journal of Alzheimer's disease, 2009-01, Vol.17 (2), p.409-422

2009

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Longitudinal evaluation of myofiber microstructural changes in a preclinical ALS model using the transverse relaxivity at tracer equilibrium (TRATE): A preliminary study

Magnetic resonance imaging, 2022-01, Vol.85, p.217-221

2022

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Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics

Muscle & nerve, 2010-07, Vol.42 (1), p.104-111

2010

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Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12524-12529

2007

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Outcome of Lumbar Epidural Steroid Injection Is Predicted by Assay of a Complex of Fibronectin and Aggrecan From Epidural Lavage

Spine (Philadelphia, Pa. 1976), 2011-08, Vol.36 (18), p.1464-1469

2011

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Novel Death Defying Domain in met entraps the active site of caspase‐3 and blocks apoptosis in hepatocytes

Hepatology (Baltimore, Md.), 2014-05, Vol.59 (5), p.2010-2021

2014

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Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes

Label-Free LC–MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis

Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide

Reactive astrocytes secrete lcn2 to promote neuron death

Neurofilaments in pre-symptomatic ALS and the impact of genotype

Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue

Molecular subtypes of ALS are associated with differences in patient prognosis

Tocilizumab is safe and tolerable and reduces C‐reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients

Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD

Biomarkers in amyotrophic lateral sclerosis: opportunities and limitations

Total protein is an effective loading control for cerebrospinal fluid western blots

Expression of Carbonic Anhydrase I in Motor Neurons and Alterations in ALS

Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

Transgenic rat model of neurodegeneration caused by mutation in the TDP gene

SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy

Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis

Optical barcoding of PLGA for multispectral analysis of nanoparticle fate in vivo

The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease

Longitudinal biomarkers in amyotrophic lateral sclerosis

Altered subcellular distribution of c-Abl in Alzheimer's disease

Longitudinal evaluation of myofiber microstructural changes in a preclinical ALS model using the transverse relaxivity at tracer equilibrium (TRATE): A preliminary study

Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics

Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis

Outcome of Lumbar Epidural Steroid Injection Is Predicted by Assay of a Complex of Fibronectin and Aggrecan From Epidural Lavage

Novel Death Defying Domain in met entraps the active site of caspase‐3 and blocks apoptosis in hepatocytes

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