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Update on targeted cancer therapies, single or in combination, and their fine tuning for precision medicine

Biomedicine & pharmacotherapy, 2020-05, Vol.125, p.110009, Article 110009

2020

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Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment

Biomedicine & pharmacotherapy, 2019-05, Vol.113, p.108750-108750, Article 108750

2019

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Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate. In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy

International journal of molecular sciences, 2023-06, Vol.24 (13), p.10507

2023

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Bio-vehicles of cytotoxic drugs for delivery to tumor specific targets for cancer precision therapy

Biomedicine & pharmacotherapy, 2021-12, Vol.144, p.112260-112260, Article 112260

2021

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Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment

PloS one, 2023-11, Vol.18 (11), p.e0294885-e0294885

2023

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Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment

PloS one, 2018-04, Vol.13 (4), p.e0196254

2018

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Production of Long-Acting CNGRC–CPG2 Fusion Proteins: New Derivatives to Overcome Drug Immunogenicity of Ligand-Directed Enzyme Prodrug Therapy for Targeted Cancer Treatment

Technology in cancer research & treatment, 2021, Vol.20, p.15330338211057371-15330338211057371

2021

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Studies on vascular response to full superantigens and superantigen derived peptides: Possible production of novel superantigen variants with less vasodilation effect for tolerable cancer immunotherapy

Biomedicine & pharmacotherapy, 2019-07, Vol.115, p.108905-108905, Article 108905

2019

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Production of “biobetter” variants of glucarpidase with enhanced enzyme activity

Biomedicine & pharmacotherapy, 2019-04, Vol.112, p.108725-108725, Article 108725

2019

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Tubulysin Synthesis Featuring Stereoselective Catalysis and Highly Convergent Multicomponent Assembly

Organic letters, 2020-07, Vol.22 (14), p.5396-5400

2020

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Production of “biobetter” glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment

European journal of pharmaceutical sciences, 2019-01, Vol.127, p.79-91

2019

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Screening for and isolation and identification of malathion-degrading bacteria: cloning and sequencing a gene that potentially encodes the malathion-degrading enzyme, carboxylestrase in soil bacteria

Biodegradation (Dordrecht), 2010-11, Vol.21 (6), p.903-913

2010

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In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy

Oncotarget, 2020-02, Vol.11 (6), p.619-633

2020

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Functional Overexpression and Purification of a Codon Optimized Synthetic Glucarpidase (Carboxypeptidase G2) in Escherichia coli

Protein Journal, 2009-12, Vol.28 (9-10), p.435-442

2009

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Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding .beta.-methylaspartase and characterization of the recombinant protein

Biochemistry (Easton), 1992-11, Vol.31 (44), p.10747-10756

1992

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Production of Synthetic Methionine-Free and Synthetic Methionine-Limited Alpha Casein: Protein Foodstuff for Patients with Homocystinuria due to Cystathionine Beta-Synthase Deficiency

The Protein Journal, 2010, Vol.29 (1), p.44-49

2010

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Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.1297-1303

2004

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Molecular analysis of a Clostridium butyricum NCIMB 7423 gene encoding 4-alpha-glucanotransferase and characterization of the recombinant enzyme produced in Escherichia coli

Microbiology (Society for General Microbiology), 1997-10, Vol.143 ( Pt 10), p.3287

1997

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Identification of a Secondary Zinc-binding Site in Staphylococcal Enterotoxin C2

The Journal of biological chemistry, 2004-01, Vol.279 (2), p.1297-1303

2004

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Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins

FEMS microbiology letters, 1998-08, Vol.165 (1), p.193-200

1998

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A simple procedure for gel electrophoresis and Northern blotting of RNA

Nucleic acids research, 1995-08, Vol.23 (16), p.3357-3358

1995

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Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI‐GalR family of repressor proteins1

FEMS microbiology letters, 1998-08, Vol.165 (1), p.193-200

1998

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Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins

FEMS microbiology letters, 1998-08, Vol.165 (1), p.193-200

1998

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The involvement of C-4 of D-glucose in the biosynthesis of the 2-deoxystreptamine ring of neomycin

Journal of the Chemical Society. Chemical communications, 1987 (1), p.12-14

1987

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Neomycin biosynthesis: the incorporation of D-6-deoxy-glucose derivatives and variously labelled glucose into the 2-deoxystreptamine ring. Postulated involvement of 2-deoxyinosose synthase in the biosynthesis

Journal of antibiotics, 1992-06, Vol.45 (6), p.984-994

1992

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Update on targeted cancer therapies, single or in combination, and their fine tuning for precision medicine

Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment

Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate. In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy

Bio-vehicles of cytotoxic drugs for delivery to tumor specific targets for cancer precision therapy

Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment

Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment

Production of Long-Acting CNGRC–CPG2 Fusion Proteins: New Derivatives to Overcome Drug Immunogenicity of Ligand-Directed Enzyme Prodrug Therapy for Targeted Cancer Treatment

Studies on vascular response to full superantigens and superantigen derived peptides: Possible production of novel superantigen variants with less vasodilation effect for tolerable cancer immunotherapy

Production of “biobetter” variants of glucarpidase with enhanced enzyme activity

Tubulysin Synthesis Featuring Stereoselective Catalysis and Highly Convergent Multicomponent Assembly

Production of “biobetter” glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment

Screening for and isolation and identification of malathion-degrading bacteria: cloning and sequencing a gene that potentially encodes the malathion-degrading enzyme, carboxylestrase in soil bacteria

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy

Functional Overexpression and Purification of a Codon Optimized Synthetic Glucarpidase (Carboxypeptidase G2) in Escherichia coli

Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding .beta.-methylaspartase and characterization of the recombinant protein

Production of Synthetic Methionine-Free and Synthetic Methionine-Limited Alpha Casein: Protein Foodstuff for Patients with Homocystinuria due to Cystathionine Beta-Synthase Deficiency

Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition

Molecular analysis of a Clostridium butyricum NCIMB 7423 gene encoding 4-alpha-glucanotransferase and characterization of the recombinant enzyme produced in Escherichia coli

Identification of a Secondary Zinc-binding Site in Staphylococcal Enterotoxin C2

Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins

A simple procedure for gel electrophoresis and Northern blotting of RNA

Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI‐GalR family of repressor proteins1

Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins

The involvement of C-4 of D-glucose in the biosynthesis of the 2-deoxystreptamine ring of neomycin

Neomycin biosynthesis: the incorporation of D-6-deoxy-glucose derivatives and variously labelled glucose into the 2-deoxystreptamine ring. Postulated involvement of 2-deoxyinosose synthase in the biosynthesis

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