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ErbB receptors: from oncogenes to targeted cancer therapies

The Journal of clinical investigation, 2007-08, Vol.117 (8), p.2051-2058

2007

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Development of Foxp3 + Regulatory T Cells Is Driven by the c-Rel Enhanceosome

Immunity (Cambridge, Mass.), 2009-12, Vol.31 (6), p.932-940

2009

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Targeting erbB Pathways in Breast Cancer: Dual Kinase Inhibition for Brain Metastasis and Prevention of p185HER2/Neu Tumor Development

Breast cancer targets and therapy, 2024-10, Vol.16, p.725-733

2024

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Disabling the mitotic spindle and tumor growth by targeting a cavity-induced allosteric site of survivin

Oncogene, 2012-04, Vol.31 (15), p.1938-1948

2012

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Challenges in Detection of Serum Oncoprotein: Relevance to Breast Cancer Diagnostics

Breast cancer targets and therapy, 2021-01, Vol.13, p.575-593

2021

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Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth

Breast cancer targets and therapy, 2021-01, Vol.13, p.419-430

2021

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A sensitive and high-throughput assay to detect low-abundance proteins in serum

Nature medicine, 2006-04, Vol.12 (4), p.473-477

2006

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Germinal center kinases in immune regulation

Cellular & molecular immunology, 2012-11, Vol.9 (6), p.439-445

2012

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In vivo molecular imaging of HER2 expression in a rat model of Barrett's esophagus adenocarcinoma

Diseases of the esophagus, 2015-05, Vol.28 (4), p.394-403

2015

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BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

Oncogene, 1998-10, Vol.17 (15), p.1939-1948

1998

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HER2/neu: mechanisms of dimerization/oligomerization

Oncogene, 2000-12, Vol.19 (53), p.6093-6101

2000

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The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors

Oncogene, 2001-09, Vol.20 (42), p.6018-6025

2001

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Disabling ErbB Receptors with Rationally Designed Exocyclic Mimetics of Antibodies: Structure−Function Analysis

Journal of medicinal chemistry, 2001-08, Vol.44 (16), p.2565-2574

2001

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Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome

DNA and cell biology, 2006-10, Vol.25 (10), p.554-562

2006

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Biochemistry and therapeutic implications of mechanisms involved in FOXP3 activity in immune suppression

Current Opinion in Immunology, 2007-10, Vol.19 (5), p.583-588

2007

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Histone deacetylase inhibitors and transplantation

Current Opinion in Immunology, 2007-10, Vol.19 (5), p.589-595

2007

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UXT is a novel centrosomal protein essential for cell viability

Molecular biology of the cell, 2005-12, Vol.16 (12), p.5857-5865

2005

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Disabling Receptor Ensembles with Rationally Designed Interface Peptidomimetics

The Journal of biological chemistry, 2002-08, Vol.277 (31), p.28330-28339

2002

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EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway

Experimental and molecular pathology, 2005-10, Vol.79 (2), p.100-107

2005

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Disabling TNF Receptor Signaling by Induced Conformational Perturbation of Tryptophan-107

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (31), p.10970-10975

2005

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Bound Water Molecules and Conformational Stabilization Help Mediate an Antigen-Antibody Association

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (3), p.1089-1093

1994

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BRCA1 and cell signaling

Oncogene, 2000-12, Vol.19 (53), p.6152-6158

2000

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Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNFα binding to its receptor

Nature biotechnology, 1997-11, Vol.15 (12), p.1266-1270

1997

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Protein Quantification from Complex Protein Mixtures Using a Proteomics Methodology with Single-Cell Resolution

Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (10), p.5497-5502

2001

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Ca2+ and K+ (BK) channels in chick hair cells are clustered and colocalized with apical–basal and tonotopic gradients

The Journal of physiology, 2004-10, Vol.560 (1), p.13-20

2004

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ErbB receptors: from oncogenes to targeted cancer therapies

Development of Foxp3 + Regulatory T Cells Is Driven by the c-Rel Enhanceosome

Targeting erbB Pathways in Breast Cancer: Dual Kinase Inhibition for Brain Metastasis and Prevention of p185HER2/Neu Tumor Development

Disabling the mitotic spindle and tumor growth by targeting a cavity-induced allosteric site of survivin

Challenges in Detection of Serum Oncoprotein: Relevance to Breast Cancer Diagnostics

Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth

A sensitive and high-throughput assay to detect low-abundance proteins in serum

Germinal center kinases in immune regulation

In vivo molecular imaging of HER2 expression in a rat model of Barrett's esophagus adenocarcinoma

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

HER2/neu: mechanisms of dimerization/oligomerization

The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors

Disabling ErbB Receptors with Rationally Designed Exocyclic Mimetics of Antibodies: Structure−Function Analysis

Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome

Biochemistry and therapeutic implications of mechanisms involved in FOXP3 activity in immune suppression

Histone deacetylase inhibitors and transplantation

UXT is a novel centrosomal protein essential for cell viability

Disabling Receptor Ensembles with Rationally Designed Interface Peptidomimetics

EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway

Disabling TNF Receptor Signaling by Induced Conformational Perturbation of Tryptophan-107

Bound Water Molecules and Conformational Stabilization Help Mediate an Antigen-Antibody Association

BRCA1 and cell signaling

Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNFα binding to its receptor

Protein Quantification from Complex Protein Mixtures Using a Proteomics Methodology with Single-Cell Resolution

Ca2+ and K+ (BK) channels in chick hair cells are clustered and colocalized with apical–basal and tonotopic gradients

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