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Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma

Clinical cancer research, 2013-11, Vol.19 (22), p.6173-6182

2013

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New Strategies in Refractory and Recurrent Neuroblastoma: Translational Opportunities to Impact Patient Outcome

Clinical cancer research, 2012-05, Vol.18 (9), p.2423-2428

2012

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Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma

Nature genetics, 2012-10, Vol.44 (10), p.1126-1130

2012

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Identification of ALK as a major familial neuroblastoma predisposition gene

Nature (London), 2008-10, Vol.455 (7215), p.930-935

2008

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Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma

Nature communications, 2022-08, Vol.13 (1), p.4814-4814, Article 4814

2022

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Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (2), p.776-784

2013

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RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (8), p.3336-3341

2011

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Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma

Clinical cancer research, 2017-04, Vol.23 (7), p.1785-1796

2017

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A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

Molecular cancer research, 2008-05, Vol.6 (5), p.735-742

2008

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Targeting ATRX Loss through Inhibition of the Cell-Cycle Checkpoint Mediator WEE1

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (3), p.375-376

Cole, Kristina A

2020

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Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma

Acta neuropathologica communications, 2022-07, Vol.10 (1), p.1-102, Article 102

2022

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CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15), p.3155-3166

2015

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Pediatric phase 2 trial of a WEE1 inhibitor, adavosertib (AZD1775), and irinotecan for relapsed neuroblastoma, medulloblastoma, and rhabdomyosarcoma

Cancer, 2023-07, Vol.129 (14), p.2245-2255

2023

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Phase I Clinical Trial of the Wee1 Inhibitor Adavosertib (AZD1775) with Irinotecan in Children with Relapsed Solid Tumors: A COG Phase I Consortium Report (ADVL1312)

Clinical cancer research, 2020-03, Vol.26 (6), p.1213-1219

2020

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The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma

Journal of cellular and molecular medicine, 2017-12, Vol.21 (12), p.3224-3230

2017

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Integrative genomics identifies LMO1 as a neuroblastoma oncogene

Nature (London), 2011-01, Vol.469 (7329), p.216-220

2011

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Endoscopic third ventriculostomy prior to resection of posterior fossa tumors in children

Child's nervous system, 2019-05, Vol.35 (5), p.789-794

2019

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Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival

JNCI : Journal of the National Cancer Institute, 2024-01, Vol.116 (1), p.149-159

2024

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Immunotherapy for pediatric brain tumors: past and present

Neuro-oncology (Charlottesville, Va.), 2019-10, Vol.21 (10), p.1226-1238

2019

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Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants

Neuro-oncology (Charlottesville, Va.), 2023-07, Vol.25 (7), p.1331-1342

2023

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Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

Nature genetics, 2009-06, Vol.41 (6), p.718-723

2009

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Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma

The New England journal of medicine, 2008-06, Vol.358 (24), p.2585-2593

2008

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Intracranial growing teratoma syndrome (iGTS): an international case series and review of the literature

Journal of neuro-oncology, 2020-05, Vol.147 (3), p.721-730

2020

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Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue

Journal of clinical oncology, 2019-02, Vol.37 (6), p.461-470

2019

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Pediatric high-grade glioma resources from the Children’s Brain Tumor Tissue Consortium

Neuro-oncology (Charlottesville, Va.), 2020-01, Vol.22 (1), p.163-165

2020

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Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma

New Strategies in Refractory and Recurrent Neuroblastoma: Translational Opportunities to Impact Patient Outcome

Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma

Identification of ALK as a major familial neuroblastoma predisposition gene

Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma

Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma

A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

Targeting ATRX Loss through Inhibition of the Cell-Cycle Checkpoint Mediator WEE1

Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus

Pediatric phase 2 trial of a WEE1 inhibitor, adavosertib (AZD1775), and irinotecan for relapsed neuroblastoma, medulloblastoma, and rhabdomyosarcoma

Phase I Clinical Trial of the Wee1 Inhibitor Adavosertib (AZD1775) with Irinotecan in Children with Relapsed Solid Tumors: A COG Phase I Consortium Report (ADVL1312)

The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma

Integrative genomics identifies LMO1 as a neuroblastoma oncogene

Endoscopic third ventriculostomy prior to resection of posterior fossa tumors in children

Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival

Immunotherapy for pediatric brain tumors: past and present

Alternative lengthening of telomeres (ALT) in pediatric high-grade gliomas can occur without ATRX mutation and is enriched in patients with pathogenic germline mismatch repair (MMR) variants

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblastoma

Intracranial growing teratoma syndrome (iGTS): an international case series and review of the literature

Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue

Pediatric high-grade glioma resources from the Children’s Brain Tumor Tissue Consortium

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