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Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C

Biomedicine & pharmacotherapy, 2021-10, Vol.142, p.111652, Article 111652

2021

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Berberine protects against ischemia-reperfusion injury: A review of evidence from animal models and clinical studies

Pharmacological research, 2019-10, Vol.148, p.104385-104385, Article 104385

2019

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GLP-1R knockdown abrogates the protective effects of liraglutide on ischaemic stroke via inhibition of M2 polarisation and activation of NLRP3 inflammasome by reducing Nrf2 activation

Neuropharmacology, 2023-10, Vol.237, p.109603-109603, Article 109603

2023

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Loganin alleviates macrophage infiltration and activation by inhibiting the MCP-1/CCR2 axis in diabetic nephropathy

Life sciences (1973), 2021-05, Vol.272, p.118808-118808, Article 118808

2021

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Anticancer polypyrrole-polyethylenimine drug-free nanozyme for precise B-cell lymphoma therapy

Biomedicine & pharmacotherapy, 2023-04, Vol.160, p.114397-114397, Article 114397

2023

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Shexiang Baoxin Pill treats acute myocardial infarction by promoting angiogenesis via GDF15-TRPV4 signaling

Biomedicine & pharmacotherapy, 2023-09, Vol.165, p.115186-115186, Article 115186

2023

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Cannabinoid receptors are involved in the protective effect of a novel curcumin derivative C66 against CCl4-induced liver fibrosis

European journal of pharmacology, 2016-05, Vol.779, p.22-30

2016

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Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization

European journal of medicinal chemistry, 2021-11, Vol.224, p.113673-113673, Article 113673

2021

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Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies

Acta pharmaceutica Sinica. B, 2021-01, Vol.11 (1), p.13-29

2021

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Antinociceptive and anti-inflammatory activities of extract and two isolated flavonoids of Carthamus tinctorius L

Journal of ethnopharmacology, 2014-02, Vol.151 (2), p.944-950

2014

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Activation of Nrf2 inhibits ferroptosis and protects against oxaliplatin-induced ototoxicity

Biomedicine & pharmacotherapy, 2023-09, Vol.165, p.115248-115248, Article 115248

2023

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Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors

European journal of pharmaceutical sciences, 2019-09, Vol.137, p.105010-105010, Article 105010

2019

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PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway

Biomedicine & pharmacotherapy, 2020-09, Vol.129, p.110356, Article 110356

2020

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Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin

Pharmacological research, 2022-03, Vol.177, p.106096-106096, Article 106096

2022

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Erinacine S, a small active component derived from Hericium erinaceus, protects oligodendrocytes and alleviates mood abnormalities in cuprizone-exposed rodents

Biomedicine & pharmacotherapy, 2024-04, Vol.173, p.116297-116297, Article 116297

2024

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Inflammation and Connexin 43 profiles in the prefrontal cortex are relevant to stress susceptibility and resilience in mice

Pharmacology, biochemistry and behavior, 2024-06, Vol.239, p.173757, Article 173757

2024

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Minocycline as a promising therapeutic strategy for chronic pain

Pharmacological research, 2018-08, Vol.134, p.305-310

2018

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Fluorine-18 labeling PEGylated 6-boronotryptophan for PET scanning of mice for assessing the pharmacokinetics for boron neutron capture therapy of brain tumors

Bioorganic & medicinal chemistry letters, 2024-06, Vol.105, p.129744-129744, Article 129744

2024

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Enhanced excitability in the infralimbic cortex produces anxiety-like behaviors

Neuropharmacology, 2013-09, Vol.72, p.148-156

2013

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A magnetic vehicle realized tumor cell-targeted radiotherapy using low-dose radiation

Journal of controlled release, 2016-03, Vol.226, p.182-192

2016

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Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the femoral head

Saudi pharmaceutical journal, 2021-12, Vol.29 (12), p.1405-1415

2021

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Wee1 inhibition by MK1775 potentiates gemcitabine through accumulated replication stress leading to apoptosis in biliary tract cancer

Biomedicine & pharmacotherapy, 2023-10, Vol.166, p.115389-115389, Article 115389

2023

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Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agents

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115190, Article 115190

2020

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Structure-based drug design to augment hit discovery

Drug discovery today, 2011-09, Vol.16 (17), p.831-839

2011

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Synergistic antitumor activity of artesunate and HDAC inhibitors through elevating heme synthesis via synergistic upregulation of ALAS1 expression

Acta pharmaceutica Sinica. B, 2019-09, Vol.9 (5), p.937-951

2019

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Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C

Berberine protects against ischemia-reperfusion injury: A review of evidence from animal models and clinical studies

GLP-1R knockdown abrogates the protective effects of liraglutide on ischaemic stroke via inhibition of M2 polarisation and activation of NLRP3 inflammasome by reducing Nrf2 activation

Loganin alleviates macrophage infiltration and activation by inhibiting the MCP-1/CCR2 axis in diabetic nephropathy

Anticancer polypyrrole-polyethylenimine drug-free nanozyme for precise B-cell lymphoma therapy

Shexiang Baoxin Pill treats acute myocardial infarction by promoting angiogenesis via GDF15-TRPV4 signaling

Cannabinoid receptors are involved in the protective effect of a novel curcumin derivative C66 against CCl4-induced liver fibrosis

Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization

Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies

Antinociceptive and anti-inflammatory activities of extract and two isolated flavonoids of Carthamus tinctorius L

Activation of Nrf2 inhibits ferroptosis and protects against oxaliplatin-induced ototoxicity

Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors

PPARγ activation mitigates mechanical allodynia in paclitaxel-induced neuropathic pain via induction of Nrf2/HO-1 signaling pathway

Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin

Erinacine S, a small active component derived from Hericium erinaceus, protects oligodendrocytes and alleviates mood abnormalities in cuprizone-exposed rodents

Inflammation and Connexin 43 profiles in the prefrontal cortex are relevant to stress susceptibility and resilience in mice

Minocycline as a promising therapeutic strategy for chronic pain

Fluorine-18 labeling PEGylated 6-boronotryptophan for PET scanning of mice for assessing the pharmacokinetics for boron neutron capture therapy of brain tumors

Enhanced excitability in the infralimbic cortex produces anxiety-like behaviors

A magnetic vehicle realized tumor cell-targeted radiotherapy using low-dose radiation

Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the femoral head

Wee1 inhibition by MK1775 potentiates gemcitabine through accumulated replication stress leading to apoptosis in biliary tract cancer

Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agents

Structure-based drug design to augment hit discovery

Synergistic antitumor activity of artesunate and HDAC inhibitors through elevating heme synthesis via synergistic upregulation of ALAS1 expression

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