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MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance

Current drug targets, 2006-07, Vol.7 (7), p.813-821

Lage, Hermann

2006

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Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer

Frontiers in pharmacology, 2020-05, Vol.11, p.599-599

2020

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Evaluation of microarray preprocessing algorithms based on concordance with RT-PCR in clinical samples

PloS one, 2009-05, Vol.4 (5), p.e5645-e5645

2009

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Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines

Molecules (Basel, Switzerland), 2009-04, Vol.14 (4), p.1639-1651

2009

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Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX

Inflammation research, 2009-10, Vol.58 (10), p.669-676

2009

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ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Clinical cancer research, 2006-12, Vol.12 (23), p.7149-7158

2006

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Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.445-452

2006

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Complete In Vivo Reversal of the Multidrug Resistance Phenotype by Jet-injection of Anti-MDR1 Short Hairpin RNA-encoding Plasmid DNA

Molecular therapy, 2008-01, Vol.16 (1), p.178-186

2008

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A Web-Based Data Warehouse on Gene Expression in Human Malignant Melanoma

Journal of investigative dermatology, 2007-02, Vol.127 (2), p.394-399

2007

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Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

Biochemical pharmacology, 2009-07, Vol.78 (1), p.45-53

2009

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Occurence of Stromal Myofibroblasts in the Invasive Ductal Breast Cancer Tissue is an Unfavourable Prognostic Factor

Anticancer research, 2007-07, Vol.27 (4C), p.2917-2924

2007

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Novel structure–activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators

Bioorganic & medicinal chemistry, 2010-07, Vol.18 (14), p.4983-4990

2010

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Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP

Molecular therapy, 2005-04, Vol.11 (4), p.508-522

2005

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Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer

Iranian journal of basic medical sciences, 2015-04, Vol.18 (4), p.385-392

2015

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Delivery of short hairpin RNAs by transkingdom RNA interference modulates the classical ABCB1-mediated multidrug-resistant phenotype of cancer cells

Cell cycle (Georgetown, Tex.), 2009-10, Vol.8 (20), p.3349-3354

2009

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Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)

Biochemical journal, 2003-12, Vol.376 (Pt 2), p.489-495

2003

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Stable and complete overcoming of MDR1 P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference

Cancer gene therapy, 2004-11, Vol.11 (11), p.699-706

2004

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Gene Therapeutic Approaches to Overcome ABCB1-Mediated Drug Resistance

Current Strategies in Cancer Gene Therapy, 2016, Vol.209, p.87-94

2016

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Estrogen Receptor Alpha Expression in Ovarian Cancer Predicts Longer Overall Survival

Pathology oncology research, 2011-09, Vol.17 (3), p.511-518

2011

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Bacteria-mediated delivery of RNAi effector molecules against viral HPV16-E7 eradicates oral squamous carcinoma cells (OSCC) via apoptosis

Cancer gene therapy, 2019-05, Vol.26 (5-6), p.166-173

2019

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Novel Insight in Structure−Activity Relationship and Bioanalysis of P-Glycoprotein Targeting Highly Potent Tetrakishydroxymethyl Substituted 3,9-Diazatetraasteranes

Journal of medicinal chemistry, 2008-09, Vol.51 (18), p.5871-5874

2008

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The Gene Polymorphism of the Angiotensin I-Converting Enzyme Correlates with Tumor Size and Patient Survival in Colorectal Cancer Patients

Neoplasia (New York, N.Y.), 2007-09, Vol.9 (9), p.716-722

2007

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Transport of phosphatidylserine via MDR1 (multidrug resistance 1)P-glycoprotein in a human gastric carcinoma cell line

Biochemical journal, 2002-07, Vol.365 (Pt 1), p.259-268

2002

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Effect of the breast-cancer resistance protein on atypical multidrug resistance

The lancet oncology, 2000-11, Vol.1 (3), p.169-175

2000

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ABC-transporters: implications on drug resistance from microorganisms to human cancers

International journal of antimicrobial agents, 2003-09, Vol.22 (3), p.188-199

Lage, Hermann

2003

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MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance

Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer

Evaluation of microarray preprocessing algorithms based on concordance with RT-PCR in clinical samples

Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines

Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX

ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

Complete In Vivo Reversal of the Multidrug Resistance Phenotype by Jet-injection of Anti-MDR1 Short Hairpin RNA-encoding Plasmid DNA

A Web-Based Data Warehouse on Gene Expression in Human Malignant Melanoma

Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

Occurence of Stromal Myofibroblasts in the Invasive Ductal Breast Cancer Tissue is an Unfavourable Prognostic Factor

Novel structure–activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators

Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP

Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer

Delivery of short hairpin RNAs by transkingdom RNA interference modulates the classical ABCB1-mediated multidrug-resistant phenotype of cancer cells

Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)

Stable and complete overcoming of MDR1 P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference

Gene Therapeutic Approaches to Overcome ABCB1-Mediated Drug Resistance

Estrogen Receptor Alpha Expression in Ovarian Cancer Predicts Longer Overall Survival

Bacteria-mediated delivery of RNAi effector molecules against viral HPV16-E7 eradicates oral squamous carcinoma cells (OSCC) via apoptosis

Novel Insight in Structure−Activity Relationship and Bioanalysis of P-Glycoprotein Targeting Highly Potent Tetrakishydroxymethyl Substituted 3,9-Diazatetraasteranes

The Gene Polymorphism of the Angiotensin I-Converting Enzyme Correlates with Tumor Size and Patient Survival in Colorectal Cancer Patients

Transport of phosphatidylserine via MDR1 (multidrug resistance 1)P-glycoprotein in a human gastric carcinoma cell line

Effect of the breast-cancer resistance protein on atypical multidrug resistance

ABC-transporters: implications on drug resistance from microorganisms to human cancers

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