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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

Nature (London), 2012-07, Vol.487 (7408), p.505-509

2012

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Moral credentials and the 2020 democratic presidential primary: No evidence that endorsing female candidates licenses people to favor men

Journal of experimental social psychology, 2021-07, Vol.95, p.104144, Article 104144

2021

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AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (20), p.5878-5890

2014

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Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers

Molecular cancer research, 2009-09, Vol.7 (9), p.1466-1476

2009

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Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers

Nature communications, 2022-11, Vol.13 (1), p.6814-6814, Article 6814

2022

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Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors

Nature communications, 2022-04, Vol.13 (1), p.2057-2057, Article 2057

2022

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Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

Oncotarget, 2014-09, Vol.5 (17), p.7328-7341

2014

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Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

PloS one, 2017-10, Vol.12 (10), p.e0185862

2017

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Evaluation of statistical approaches for association testing in noisy drug screening data

BMC bioinformatics, 2022-05, Vol.23 (1), p.188-188, Article 188

2022

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Orchestrating and sharing large multimodal data for transparent and reproducible research

Nature communications, 2021-10, Vol.12 (1), p.5797-5797, Article 5797

2021

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Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma

Cancers, 2024-08, Vol.16 (16), p.2914

2024

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Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines

Bioorganic & medicinal chemistry, 2008-04, Vol.16 (7), p.3626-3631

2008

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Oncogenic Activating Mutations Are Associated with Local Copy Gain

Molecular cancer research, 2009-08, Vol.7 (8), p.1244-1252

2009

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Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

PloS one, 2018, Vol.13 (1), p.e0192059-e0192059

2018

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Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

iScience, 2021-07, Vol.24 (7), p.102807-102807, Article 102807

2021

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Autocrine CSF-1R Activation Promotes Src-Dependent Disruption of Mammary Epithelial Architecture

The Journal of cell biology, 2004-04, Vol.165 (2), p.263-273

2004

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Reproducible pharmacogenomic profiling of cancer cell line panels

Nature (London), 2016-05, Vol.533 (7603), p.333-337

2016

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Do past and present abiotic conditions explain variation in the nutritional quality of wildflower pollens for bees?

Evolutionary ecology, 2024-08

2024

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USP7 small-molecule inhibitors interfere with ubiquitin binding

Nature (London), 2017-10, Vol.550 (7677), p.534-538

2017

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Towards in vitro in vivo correlation for modified release subcutaneously administered insulins

European journal of pharmaceutical sciences, 2020-03, Vol.145, p.105239-105239, Article 105239

2020

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Cross-coupling by a noncanonical mechanism involving the addition of aryl halide to Cu(II)

Science (American Association for the Advancement of Science), 2023-09, Vol.381 (6662), p.1079-1085

2023

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PharmacoDB 2.0: improving scalability and transparency of in vitro pharmacogenomics analysis

Nucleic acids research, 2022-01, Vol.50 (D1), p.D1348-D1357

2022

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ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy

Clinical cancer research, 2018-08, Vol.24 (16), p.4044-4055

2018

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Regulation of the 75-kDa Subunit of Mitochondrial Complex I by Iron

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27685-27692

2001

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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

Moral credentials and the 2020 democratic presidential primary: No evidence that endorsing female candidates licenses people to favor men

AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs

Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers

Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers

Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors

Overcoming EMT-associated resistance to anti-cancer drugs via Src/FAK pathway inhibition

Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

Evaluation of statistical approaches for association testing in noisy drug screening data

Orchestrating and sharing large multimodal data for transparent and reproducible research

Computational Modeling of Drug Response Identifies Mutant-Specific Constraints for Dosing panRAF and MEK Inhibitors in Melanoma

Synthesis and anti-cancer activity of benzothiazole containing phthalimide on human carcinoma cell lines

Oncogenic Activating Mutations Are Associated with Local Copy Gain

Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors

Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

Autocrine CSF-1R Activation Promotes Src-Dependent Disruption of Mammary Epithelial Architecture

Reproducible pharmacogenomic profiling of cancer cell line panels

Do past and present abiotic conditions explain variation in the nutritional quality of wildflower pollens for bees?

USP7 small-molecule inhibitors interfere with ubiquitin binding

Towards in vitro in vivo correlation for modified release subcutaneously administered insulins

Cross-coupling by a noncanonical mechanism involving the addition of aryl halide to Cu(II)

ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma

PharmacoDB 2.0: improving scalability and transparency of in vitro pharmacogenomics analysis

ERK Mutations and Amplification Confer Resistance to ERK-Inhibitor Therapy

Regulation of the 75-kDa Subunit of Mitochondrial Complex I by Iron

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