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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

PloS one, 2018-05, Vol.13 (5), p.e0196791-e0196791

2018

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Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24155-24167

2009

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Progress and challenges in the optimization of toxin peptides for development as pain therapeutics

Current opinion in chemical biology, 2017-06, Vol.38, p.70-79

2017

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Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS

Journal of pharmacological and toxicological methods, 2009-05, Vol.59 (3), p.171-180

2009

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Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein

Science (American Association for the Advancement of Science), 2003-02, Vol.299 (5608), p.884-887

2003

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Probing the S100 protein family through genomic and functional analysis

Genomics (San Diego, Calif.), 2004-07, Vol.84 (1), p.10-22

2004

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Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2299-2314

2015

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Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3427-3438

2021

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Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6784-6802

2015

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Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx‑1

ACS chemical biology, 2019-01, Vol.14 (1), p.118-130

2019

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Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity

Journal of medicinal chemistry, 2008-05, Vol.51 (9), p.2758-2765

2008

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Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates

ACS chemical biology, 2017-09, Vol.12 (9), p.2427-2435

2017

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Direct Quantitative Analysis of a 20 kDa PEGylated Human Calcitonin Gene Peptide Antagonist in Cynomolgus Monkey Serum Using In-Source CID and UPLC-MS/MS

Journal of the American Society for Mass Spectrometry, 2011-09, Vol.22 (9), p.1660-1667

2011

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Identification of Potent, Selective, and Metabolically Stable Peptide Antagonists to the Calcitonin Gene-Related Peptide (CGRP) Receptor

Journal of medicinal chemistry, 2008-12, Vol.51 (24), p.7889-7897

2008

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A Chemical Approach to the Pharmaceutical Optimization of an Anti-HIV Protein

Journal of the American Chemical Society, 2007-10, Vol.129 (43), p.13153-13159

2007

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Three-Dimensional Solution Structure of α-Conotoxin MII by NMR Spectroscopy: Effects of Solution Environment on Helicity

Biochemistry (Easton), 1998-11, Vol.37 (45), p.15621-15630

1998

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Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor

The Journal of biological chemistry, 1999-12, Vol.274 (51), p.36559-36564

1999

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Leu(10) of alpha-conotoxin PnIB confers potency for neuronal nicotinic responses in bovine chromaffin cells

European journal of pharmacology, 2000-03, Vol.390 (3), p.229

2000

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Isolation and physical characterization of an alpha1-acid-glycoprotein from human serum (author's transl)

Sangre (Zaragoza), 1975, Vol.20 (2), p.113

1975

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Obtaining monoclonal antibodies against human immunoglobulins

Salud pública de México, 1985-05, Vol.27 (3), p.194-198

1985

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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

Progress and challenges in the optimization of toxin peptides for development as pain therapeutics

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS

Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein

Probing the S100 protein family through genomic and functional analysis

Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel

Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx‑1

Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity

Engineering Na V 1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics

Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates

Direct Quantitative Analysis of a 20 kDa PEGylated Human Calcitonin Gene Peptide Antagonist in Cynomolgus Monkey Serum Using In-Source CID and UPLC-MS/MS

Identification of Potent, Selective, and Metabolically Stable Peptide Antagonists to the Calcitonin Gene-Related Peptide (CGRP) Receptor

A Chemical Approach to the Pharmaceutical Optimization of an Anti-HIV Protein

Three-Dimensional Solution Structure of α-Conotoxin MII by NMR Spectroscopy: Effects of Solution Environment on Helicity

Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor

Leu(10) of alpha-conotoxin PnIB confers potency for neuronal nicotinic responses in bovine chromaffin cells

Isolation and physical characterization of an alpha1-acid-glycoprotein from human serum (author's transl)

Obtaining monoclonal antibodies against human immunoglobulins

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