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SGLT2 inhibition improves PI3Kα inhibitor–induced hyperglycemia: findings from preclinical animal models and from patients in the BYLieve and SOLAR-1 trials

Breast cancer research and treatment, 2024-11, Vol.208 (1), p.111-121

2024

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Synthesis, molecular docking study, MD simulation, ADMET, and drug likeness of new thiazolo[3,2-a]pyridine-6,8-dicarbonitrile derivatives as potential anti-diabetic agents

PloS one, 2024-09, Vol.19 (9), p.e0306973

2024

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Thiazole Functionalization of Thiosemicarbazone for Cu(II) Complexation: Moving toward Highly Efficient Anticancer Drugs with Promising Oral Bioavailability

Molecules (Basel, Switzerland), 2024-08, Vol.29 (16), p.3832

2024

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Fungicidal Activity of Novel 6‑Isothiazol-5-ylpyrimidin-4-amine-Containing Compounds Targeting Complex I Reduced Nicotinamide Adenine Dinucleotide Oxidoreductase

Journal of agricultural and food chemistry, 2024-10, Vol.72 (40), p.22082-22091

2024

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Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents

Bioorganic chemistry, 2024-10, Vol.151, p.107682, Article 107682

2024

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Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae

Open biology, 2024-07, Vol.14 (7), p.240057

2024

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Formulation and Evaluation of Meloxicam Hybrid nano Particles

AAPS PharmSciTech, 2024-07, Vol.25 (6), p.172, Article 172

2024

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Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in silico study

Bioorganic chemistry, 2024-11, Vol.152, p.107760, Article 107760

2024

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Preparation, optimisation, and properties of O-carboxymethyl chitosan-g-cholesterol succinic acid monoester polymer nanomicelles

Biomedical materials (Bristol), 2024-08, Vol.19 (5), p.55036

2024

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PPARβ/δ Agonist GW0742 Modulates Microglial and Astroglial Gene Expression in a Rat Model of Temporal Lobe Epilepsy

International journal of molecular sciences, 2024-09, Vol.25 (18), p.10015

2024

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Indoor residual spraying of experimental huts in Cameroon highlights the potential of Fludora® Fusion to control wild pyrethroid-resistant malaria vectors

BMC infectious diseases, 2024-07, Vol.24 (1), p.733-14, Article 733

2024

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Ligand-Receptor Interactions and Structure-Function Relationships in Off-Target Binding of the β 3 -Adrenergic Agonist Mirabegron to α 1A -Adrenergic Receptors

International journal of molecular sciences, 2024-07, Vol.25 (13)

2024

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The Synergistic Effect of Baloxavir and Neuraminidase Inhibitors against Influenza Viruses In Vitro

Viruses, 2024-09, Vol.16 (9), p.1467

2024

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PPARβ/δ attenuates hepatic fibrosis by reducing SMAD3 phosphorylation and p300 levels via AMPK in hepatic stellate cells

Biomedicine & pharmacotherapy, 2024-10, Vol.179, p.117303, Article 117303

2024

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4-Methylthiazole triggers apoptosis and mitochondrial disruption in HL-60 cells

Molecular biology reports, 2024-12, Vol.51 (1), p.997, Article 997

2024

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Thiazolium salt mimics the non-coenzyme effects of vitamin B 1 in rat synaptosomes

Neurochemistry international, 2024-09, Vol.178, p.105791

2024

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Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection

Science advances, 2024-08, Vol.10 (31), p.eadn7979

2024

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Cromolyn sodium and masitinib combination inhibits fibroblast-myofibroblast transition and exerts additive cell-protective and antioxidant effects on a bleomycin-induced in vitro fibrosis model

Pharmacology research & perspectives, 2024-10, Vol.12 (5), p.e70018

2024

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Honeybee gut bacterial strain improved survival and gut microbiota homeostasis in Apis mellifera exposed in vivo to clothianidin

Microbiology spectrum, 2024-10, Vol.12 (10), p.e0057824

2024

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β-Adrenoceptor Signaling Activation Improves Bladder Fibrosis by Inhibiting Extracellular Matrix Deposition of Bladder Outlet Obstruction

Frontiers in bioscience (Landmark. Print), 2024-09, Vol.29 (9), p.336

2024

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Investigation of Mirabegron-loaded Nanostructured Lipid Carriers for Improved Bioabsorption: Formulation, Statistical Optimization, and In-Vivo Evaluation

AAPS PharmSciTech, 2024-09, Vol.25 (7), p.222, Article 222

2024

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Intestinal Absorption Site-Guided Development and Evaluation of Oral Disintegrating Controlled Release Tablets of Mirabegron

AAPS PharmSciTech, 2024-07, Vol.25 (6), p.167, Article 167

2024

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2-Phenylbenzothiazolyl iridium complexes as inhibitors and probes of amyloid β aggregation

Dalton transactions : an international journal of inorganic chemistry, 2024-08, Vol.53 (34), p.14258-14264

2024

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Transport and inhibition mechanisms of the human noradrenaline transporter

Nature (London), 2024-08, Vol.632 (8026), p.930-937

2024

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Emerging therapeutic avenues against Cryptosporidium: A comprehensive review

Veterinary parasitology, 2024-10, Vol.331, p.110279, Article 110279

2024

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SGLT2 inhibition improves PI3Kα inhibitor–induced hyperglycemia: findings from preclinical animal models and from patients in the BYLieve and SOLAR-1 trials

Synthesis, molecular docking study, MD simulation, ADMET, and drug likeness of new thiazolo[3,2-a]pyridine-6,8-dicarbonitrile derivatives as potential anti-diabetic agents

Thiazole Functionalization of Thiosemicarbazone for Cu(II) Complexation: Moving toward Highly Efficient Anticancer Drugs with Promising Oral Bioavailability

Fungicidal Activity of Novel 6‑Isothiazol-5-ylpyrimidin-4-amine-Containing Compounds Targeting Complex I Reduced Nicotinamide Adenine Dinucleotide Oxidoreductase

Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents

Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae

Formulation and Evaluation of Meloxicam Hybrid nano Particles

Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in silico study

Preparation, optimisation, and properties of O-carboxymethyl chitosan-g-cholesterol succinic acid monoester polymer nanomicelles

PPARβ/δ Agonist GW0742 Modulates Microglial and Astroglial Gene Expression in a Rat Model of Temporal Lobe Epilepsy

Indoor residual spraying of experimental huts in Cameroon highlights the potential of Fludora® Fusion to control wild pyrethroid-resistant malaria vectors

Ligand-Receptor Interactions and Structure-Function Relationships in Off-Target Binding of the β 3 -Adrenergic Agonist Mirabegron to α 1A -Adrenergic Receptors

The Synergistic Effect of Baloxavir and Neuraminidase Inhibitors against Influenza Viruses In Vitro

PPARβ/δ attenuates hepatic fibrosis by reducing SMAD3 phosphorylation and p300 levels via AMPK in hepatic stellate cells

4-Methylthiazole triggers apoptosis and mitochondrial disruption in HL-60 cells

Thiazolium salt mimics the non-coenzyme effects of vitamin B 1 in rat synaptosomes

Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection

Cromolyn sodium and masitinib combination inhibits fibroblast-myofibroblast transition and exerts additive cell-protective and antioxidant effects on a bleomycin-induced in vitro fibrosis model

Honeybee gut bacterial strain improved survival and gut microbiota homeostasis in Apis mellifera exposed in vivo to clothianidin

β-Adrenoceptor Signaling Activation Improves Bladder Fibrosis by Inhibiting Extracellular Matrix Deposition of Bladder Outlet Obstruction

Investigation of Mirabegron-loaded Nanostructured Lipid Carriers for Improved Bioabsorption: Formulation, Statistical Optimization, and In-Vivo Evaluation

Intestinal Absorption Site-Guided Development and Evaluation of Oral Disintegrating Controlled Release Tablets of Mirabegron

2-Phenylbenzothiazolyl iridium complexes as inhibitors and probes of amyloid β aggregation

Transport and inhibition mechanisms of the human noradrenaline transporter

Emerging therapeutic avenues against Cryptosporidium: A comprehensive review

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