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Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (22), p.E5106-E5114

2018

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Identification and characterization of extrachromosomal circular DNA in maternal plasma

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (3), p.1658-1665

2020

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Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin

Genome research, 2019-03, Vol.29 (3), p.418-427

2019

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Detection and Characterization of Placental MicroRNAs in Maternal Plasma

Clinical chemistry (Baltimore, Md.), 2008-03, Vol.54 (3), p.482-490

2008

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Microfluidics Digital PCR Reveals a Higher than Expected Fraction of Fetal DNA in Maternal Plasma

Clinical chemistry (Baltimore, Md.), 2008-10, Vol.54 (10), p.1664-1672

2008

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High-resolution profiling of fetal DNA clearance from maternal plasma by massively parallel sequencing

Clinical chemistry (Baltimore, Md.), 2013-08, Vol.59 (8), p.1228-1237

2013

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Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.E5302-E5311

2014

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Noninvasive prenatal methylomic analysis by genomewide bisulfite sequencing of maternal plasma DNA

Clinical chemistry (Baltimore, Md.), 2013-11, Vol.59 (11), p.1583-1594

2013

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Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies

Science (American Association for the Advancement of Science), 2021-04, Vol.372 (6538)

2021

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Methy-Pipe: an integrated bioinformatics pipeline for whole genome bisulfite sequencing data analysis

PloS one, 2014-06, Vol.9 (6), p.e100360-e100360

2014

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Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.E1317-E1325

2015

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Cell-free DNA for Colorectal Cancer Screening

The New England journal of medicine, 2024-03, Vol.390 (11), p.1047-1050

2024

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Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (2), p.641-649

2019

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Enhanced cancer detection from cell-free DNA

Nature biotechnology, 2022-04, Vol.40 (4), p.473-474

2022

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Genome-wide detection of cytosine methylation by single molecule real-time sequencing

Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (5)

2021

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Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA

PloS one, 2012-05, Vol.7 (5), p.e38154-e38154

2012

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Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20458-20463

2008

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Noninvasive Prenatal Diagnosis of Congenital Adrenal Hyperplasia Using Cell-Free Fetal DNA in Maternal Plasma

The journal of clinical endocrinology and metabolism, 2014-06, Vol.99 (6), p.E1022-E1030

2014

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Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus

Science translational medicine, 2010-12, Vol.2 (61), p.61ra91

2010

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Noninvasive Prenatal Diagnosis of Fetal Chromosomal Aneuploidies by Maternal Plasma Nucleic Acid Analysis

Clinical chemistry (Baltimore, Md.), 2008-03, Vol.54 (3), p.461-466

2008

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Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.18761-18768

2013

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Screening of Fetal Chromosomal Aneuploidy by Noninvasive Prenatal Testing: From Innovation to Setting Public Health Agendas to Potential Impact on Other Fields

Clinical chemistry (Baltimore, Md.), 2020-01, Vol.66 (1), p.25-28

Dennis Lo, Y M

2020

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Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (23), p.8583-8588

2014

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Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (22), p.E5115-E5124

2018

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Single-Molecule Sequencing Enables Long Cell-Free DNA Detection and Direct Methylation Analysis for Cancer Patients

Clinical chemistry (Baltimore, Md.), 2022-09, Vol.68 (9), p.1151-1163

2022

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Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing

Identification and characterization of extrachromosomal circular DNA in maternal plasma

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin

Detection and Characterization of Placental MicroRNAs in Maternal Plasma

Microfluidics Digital PCR Reveals a Higher than Expected Fraction of Fetal DNA in Maternal Plasma

High-resolution profiling of fetal DNA clearance from maternal plasma by massively parallel sequencing

Plasma DNA aberrations in systemic lupus erythematosus revealed by genomic and methylomic sequencing

Noninvasive prenatal methylomic analysis by genomewide bisulfite sequencing of maternal plasma DNA

Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies

Methy-Pipe: an integrated bioinformatics pipeline for whole genome bisulfite sequencing data analysis

Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

Cell-free DNA for Colorectal Cancer Screening

Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA

Enhanced cancer detection from cell-free DNA

Genome-wide detection of cytosine methylation by single molecule real-time sequencing

Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA

Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma

Noninvasive Prenatal Diagnosis of Congenital Adrenal Hyperplasia Using Cell-Free Fetal DNA in Maternal Plasma

Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus

Noninvasive Prenatal Diagnosis of Fetal Chromosomal Aneuploidies by Maternal Plasma Nucleic Acid Analysis

Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

Screening of Fetal Chromosomal Aneuploidy by Noninvasive Prenatal Testing: From Innovation to Setting Public Health Agendas to Potential Impact on Other Fields

Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing

Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma

Single-Molecule Sequencing Enables Long Cell-Free DNA Detection and Direct Methylation Analysis for Cancer Patients

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