UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.7923-7956

2020

Volltextzugriff (PDF)

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9184-9204

2017

Volltextzugriff (PDF)

Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)‑1-((S)‑2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy‑N‑(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.599-618

2018

Volltextzugriff (PDF)

Substituted N‑Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.7108-7122

2017

Volltextzugriff (PDF)

Novel 3‑Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4488-4510

2016

Volltextzugriff (PDF)

Myeloid Differentiation Primary Response Protein 88 (MyD88): The Central Hub of TLR/IL-1R Signaling

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13316-13329

2020

Volltextzugriff (PDF)

Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3548-3571

2015

Volltextzugriff (PDF)

2‑Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth

Journal of medicinal chemistry, 2020-03, Vol.63 (5), p.2308-2324

2020

Volltextzugriff (PDF)

Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2‑Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice

Journal of medicinal chemistry, 2024-04, Vol.67 (8), p.6344-6364

2024

Volltextzugriff (PDF)

Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer’s Agents: Synthesis and Biological Evaluation

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5823-5846

2016

Volltextzugriff (PDF)

Sortase A Inhibitors: Recent Advances and Future Perspectives

Journal of medicinal chemistry, 2015-12, Vol.58 (23), p.9108-9123

2015

Volltextzugriff (PDF)

Discovery of Quaternized Pyridine-Thiazole-Pleuromutilin Derivatives with Broad-Spectrum Antibacterial and Potent Anti-MRSA Activity

Journal of medicinal chemistry, 2023-04, Vol.66 (7), p.5061-5078

2023

Volltextzugriff (PDF)

Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)

Journal of medicinal chemistry, 2009-05, Vol.52 (9), p.3028-3038

2009

Volltextzugriff (PDF)

Second-Generation Phenylthiazole Antibiotics with Enhanced Pharmacokinetic Properties

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4900-4912

2016

Volltextzugriff (PDF)

Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6458-6467

2014

Volltextzugriff (PDF)

Insight from Linker Investigations: Discovery of a Novel Phenylbenzothiazole Necroptosis Inhibitor Targeting Receptor-Interacting Protein Kinase 1 (RIPK1) from a Phenoxybenzothiazole Compound with Dual RIPK1/3 Targeting Activity

Journal of medicinal chemistry, 2023-11, Vol.66 (22), p.15288-15308

2023

Volltextzugriff (PDF)

Structure-Based Discovery of Substituted 4,5′-Bithiazoles as Novel DNA Gyrase Inhibitors

Journal of medicinal chemistry, 2012-07, Vol.55 (14), p.6413-6426

2012

Volltextzugriff (PDF)

Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5381-5394

2014

Volltextzugriff (PDF)

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms

Journal of medicinal chemistry, 2017-01, Vol.60 (1), p.290-306

2017

Volltextzugriff (PDF)

Structure–Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.391-417

2020

Volltextzugriff (PDF)

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2‑d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

Journal of medicinal chemistry, 2015-07, Vol.58 (14), p.5501-5521

2015

Volltextzugriff (PDF)

Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice

Journal of medicinal chemistry, 2009-04, Vol.52 (7), p.1864-1872

2009

Volltextzugriff (PDF)

Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting InhA in Mycobacterium tuberculosis

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8533-8542

2013

Volltextzugriff (PDF)

Potent and Selective Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Heterobifunctional Small-molecule Degraders

Journal of medicinal chemistry, 2020-12, Vol.63 (24), p.15883-15905

2020

Volltextzugriff (PDF)

1 – 25 von 633

Suche als RSS-Feed

Aktive Filter

KollektionWiley Online Library All Journals

Nur zeigenMit Volltextzugriff

Zeitschrift / SerieJournal Of Medicinal Chemistry

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(633)

Publikationsform

Artikel
(633)

Sprache

Englisch
(633)
Japanisch
(122)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

MEDLINE
(633)
Wiley Journals
(0)

Zeitschrift / Serie

Menü

Weitere Dienste

Einstellungen

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Substituted N‑Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

Novel 3‑Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

Myeloid Differentiation Primary Response Protein 88 (MyD88): The Central Hub of TLR/IL-1R Signaling

Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors

2‑Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth

Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2‑Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice

Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer’s Agents: Synthesis and Biological Evaluation

Sortase A Inhibitors: Recent Advances and Future Perspectives

Discovery of Quaternized Pyridine-Thiazole-Pleuromutilin Derivatives with Broad-Spectrum Antibacterial and Potent Anti-MRSA Activity

Discovery of the Potent and Selective M1 PAM-Agonist N‑[(3R,4S)‑3-Hydroxytetrahydro‑2H‑pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects

Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)

Second-Generation Phenylthiazole Antibiotics with Enhanced Pharmacokinetic Properties

Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor

Insight from Linker Investigations: Discovery of a Novel Phenylbenzothiazole Necroptosis Inhibitor Targeting Receptor-Interacting Protein Kinase 1 (RIPK1) from a Phenoxybenzothiazole Compound with Dual RIPK1/3 Targeting Activity

Structure-Based Discovery of Substituted 4,5′-Bithiazoles as Novel DNA Gyrase Inhibitors

Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms

Structure–Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2‑d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice

Methyl-Thiazoles: A Novel Mode of Inhibition with the Potential to Develop Novel Inhibitors Targeting InhA in Mycobacterium tuberculosis

Potent and Selective Mitogen-Activated Protein Kinase Kinase 1/2 (MEK1/2) Heterobifunctional Small-molecule Degraders

Aktive Filter

Suchergebnisse filtern