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N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

Bioorganic & medicinal chemistry, 2018-10, Vol.26 (18), p.5169-5180

2018

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Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

European journal of medicinal chemistry, 2015-06, Vol.97, p.699-718

2015

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Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives

European journal of medicinal chemistry, 2018-05, Vol.151, p.248-260

2018

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Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

Cell metabolism, 2015-01, Vol.21 (1), p.33-38

2015

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Recent developments of 2-aminothiazoles in medicinal chemistry

European journal of medicinal chemistry, 2016-02, Vol.109, p.89-98

2016

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Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions

The Lancet (British edition), 2021-09, Vol.398 (10306), p.1184-1194

2021

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Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties

European journal of medicinal chemistry, 2015-01, Vol.90, p.666-683

2015

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Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

European journal of medicinal chemistry, 2018-02, Vol.145, p.35-40

2018

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Direct oral anticoagulants: evidence and unresolved issues

The Lancet (British edition), 2020-11, Vol.396 (10264), p.1767-1776

2020

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Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Bioorganic & medicinal chemistry, 2020-04, Vol.28 (7), p.115403-115403, Article 115403

2020

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Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

European journal of medicinal chemistry, 2018-02, Vol.146, p.15-37

2018

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Synthesis, antimicrobial activity and advances in structure-activity relationships (SARs) of novel tri-substituted thiazole derivatives

European journal of medicinal chemistry, 2016-11, Vol.123, p.508-513

2016

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Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

International journal of biological macromolecules, 2020-11, Vol.163, p.1970-1988

2020

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Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors

European journal of medicinal chemistry, 2019-11, Vol.182 (C), p.111648-111648, Article 111648

2019

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Synthesis and antiviral activity of new pyrazole and thiazole derivatives

European journal of medicinal chemistry, 2009-09, Vol.44 (9), p.3746-3753

2009

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Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring

European journal of medicinal chemistry, 2010-02, Vol.45 (2), p.651-660

2010

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Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

Bioorganic chemistry, 2020-05, Vol.98, p.103761, Article 103761

2020

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2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents

European journal of medicinal chemistry, 2021-01, Vol.210, p.112953, Article 112953

2021

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Design, synthesis, and SAR study of novel 4,5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsis

European journal of medicinal chemistry, 2021-12, Vol.225, p.113743-113743, Article 113743

2021

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Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3741-3748

2013

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Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles

European journal of medicinal chemistry, 2013-09, Vol.67, p.54-59

2013

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Design, synthesis and biological assessment of new selective COX-2 inhibitors including methyl sulfonyl moiety

European journal of medicinal chemistry, 2021-01, Vol.209, p.112918-112918, Article 112918

2021

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Recent developments and biological activities of thiazolidinone derivatives: A review

Bioorganic & medicinal chemistry, 2012-06, Vol.20 (11), p.3378-3395

2012

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Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase

European journal of medicinal chemistry, 2018-10, Vol.158, p.34-50

2018

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Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel

Neuron (Cambridge, Mass.), 2020-03, Vol.105 (5), p.882-894.e5

2020

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N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives

Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

Recent developments of 2-aminothiazoles in medicinal chemistry

Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions

Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties

Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

Direct oral anticoagulants: evidence and unresolved issues

Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

Synthesis, antimicrobial activity and advances in structure-activity relationships (SARs) of novel tri-substituted thiazole derivatives

Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2,4-disubstituted thiazole ring

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents

Design, synthesis, and SAR study of novel 4,5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsis

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles

Design, synthesis and biological assessment of new selective COX-2 inhibitors including methyl sulfonyl moiety

Recent developments and biological activities of thiazolidinone derivatives: A review

Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase

Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel

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