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Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

European journal of medicinal chemistry, 2015-06, Vol.97, p.699-718

2015

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Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives

Current topics in medicinal chemistry, 2016-10, Vol.16 (26), p.2841

2016

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Cancer Selective Target Degradation by Folate-Caged PROTACs

Journal of the American Chemical Society, 2021-05, Vol.143 (19), p.7380-7387

2021

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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6557), p.931-936

2021

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Seed coating with a neonicotinoid insecticide negatively affects wild bees

Nature (London), 2015-05, Vol.521 (7550), p.77-80

2015

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Thiazole Compounds as Antiviral Agents: An Update

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2020-01, Vol.16 (1), p.4

2020

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Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist

Cell metabolism, 2015-01, Vol.21 (1), p.33-38

2015

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Bees prefer foods containing neonicotinoid pesticides

Nature (London), 2015-05, Vol.521 (7550), p.74-76

2015

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Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.7923-7956

2020

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Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives

European journal of medicinal chemistry, 2018-05, Vol.151, p.248-260

2018

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Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9184-9204

2017

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Thiazoles and Thiazolidinones as COX/LOX Inhibitors

Molecules (Basel, Switzerland), 2018-03, Vol.23 (3), p.685

2018

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Recent developments of 2-aminothiazoles in medicinal chemistry

European journal of medicinal chemistry, 2016-02, Vol.109, p.89-98

2016

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An Overview of the Synthesis and Antimicrobial, Antiprotozoal, and Antitumor Activity of Thiazole and Bisthiazole Derivatives

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.624

2021

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Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions

The Lancet (British edition), 2021-09, Vol.398 (10306), p.1184-1194

2021

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Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)‑1-((S)‑2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy‑N‑(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.599-618

2018

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Imidazothiazole and related heterocyclic systems. Synthesis, chemical and biological properties

European journal of medicinal chemistry, 2015-01, Vol.90, p.666-683

2015

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Thiazole Ring-A Biologically Active Scaffold

Molecules (Basel, Switzerland), 2021-05, Vol.26 (11), p.3166

2021

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Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

European journal of medicinal chemistry, 2018-02, Vol.145, p.35-40

2018

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Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Bioorganic & medicinal chemistry, 2020-04, Vol.28 (7), p.115403-115403, Article 115403

2020

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Direct oral anticoagulants: evidence and unresolved issues

The Lancet (British edition), 2020-11, Vol.396 (10264), p.1767-1776

2020

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Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

European journal of medicinal chemistry, 2018-02, Vol.146, p.15-37

2018

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Substituted N‑Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.7108-7122

2017

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Novel 3‑Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4488-4510

2016

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