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Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development

Journal of clinical medicine, 2020-06, Vol.9 (6), p.2004

2020

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In utero nanoparticle delivery for site-specific genome editing

Nature communications, 2018-06, Vol.9 (1), p.2481-11, Article 2481

2018

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Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing

Molecules (Basel, Switzerland), 2018-03, Vol.23 (3), p.632

2018

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Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

Molecules (Basel, Switzerland), 2020-02, Vol.25 (3), p.735

2020

Volltextzugriff (PDF)

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

Nature communications, 2016-10, Vol.7 (1), p.13304-14, Article 13304

2016

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Distribution of polymer nanoparticles by convection-enhanced delivery to brain tumors

Journal of controlled release, 2016-06, Vol.232, p.103-112

2016

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Direct targeting of amplified gene loci for proapoptotic anticancer therapy

Nature biotechnology, 2022-03, Vol.40 (3), p.325

2022

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Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

Molecular therapy. Nucleic acids, 2017-12, Vol.9 (C), p.111-119

2017

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Abstract 1075: Chemically modified gamma PNAs targeting oncomiR-210 as a potential anticancer therapy

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1075-1075

2016

Volltextzugriff (PDF)

Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition

Current gene therapy, 2014-01, Vol.14 (5), p.331

2014

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Systemic Targeting of Therapeutic RNA to Tumors Via a Cell-Penetrating and RNA-Binding Antibody

Quijano, Elias

2023

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Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities

The Yale journal of biology & medicine, 2017-12, Vol.90 (4), p.583-598

2017

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Abstract LB169: Systemic Administration of an antibody/RNA complex results in tumor specific delivery of immunostimulatory RNAs and tumor growth suppression in a mouse model of melanoma

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.LB169-LB169

2021

Volltextzugriff (PDF)

Abstract P135: Systemic targeting of a CNS tumor (medulloblastoma) using a novel cell-penetrating, nucleic acid binding, monoclonal antibody

Molecular cancer therapeutics, 2021-12, Vol.20 (12_Supplement), p.P135-P135

2021

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Optimizing biodegradable nanoparticle size for tissue-specific delivery

Journal of controlled release, 2019-11, Vol.314, p.92-101

2019

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Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium

Nature communications, 2015-04, Vol.6 (1), p.6952-6952, Article 6952

2015

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Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation

Nucleic acids research, 2022-06, Vol.50 (10), p.e59

2022

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Fas ligand and nitric oxide combination to control smooth muscle growth while sparing endothelium

Biomaterials, 2019-08, Vol.212, p.28-38

2019

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Poly(Lactic-co-Glycolic Acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2105, p.261

2020

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Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery

Journal of controlled release, 2012-11, Vol.164 (1), p.41-48

2012

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From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (4), p.E802-E811

2018

Volltextzugriff (PDF)

Identification of Optimized Peptide Nucleic Acid (PNA) Designs for Nuclease-Free Gene Editing in Sickle Cell Disease Hematopoietic Stem and Progenitor Cells (HSPCs)

Blood, 2019-11, Vol.134 (Supplement_1), p.4645-4645

2019

Volltextzugriff (PDF)

Systemic delivery of blood-brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue

Journal of drug targeting, 2015-01, Vol.23 (7-8), p.736-749

2015

Volltextzugriff (PDF)

Abstract 755: Fas Ligand- and Nitric Oxide-Releasing Stent

Circulation research, 2019-08, Vol.125 (Suppl_1)

2019

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Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation

Journal of cystic fibrosis, 2024-08

2024

Volltextzugriff (PDF)

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Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development

In utero nanoparticle delivery for site-specific genome editing

Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing

Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

Distribution of polymer nanoparticles by convection-enhanced delivery to brain tumors

Direct targeting of amplified gene loci for proapoptotic anticancer therapy

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

Abstract 1075: Chemically modified gamma PNAs targeting oncomiR-210 as a potential anticancer therapy

Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition

Systemic Targeting of Therapeutic RNA to Tumors Via a Cell-Penetrating and RNA-Binding Antibody

Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities

Abstract LB169: Systemic Administration of an antibody/RNA complex results in tumor specific delivery of immunostimulatory RNAs and tumor growth suppression in a mouse model of melanoma

Abstract P135: Systemic targeting of a CNS tumor (medulloblastoma) using a novel cell-penetrating, nucleic acid binding, monoclonal antibody

Optimizing biodegradable nanoparticle size for tissue-specific delivery

Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium

Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation

Fas ligand and nitric oxide combination to control smooth muscle growth while sparing endothelium

Poly(Lactic-co-Glycolic Acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo

Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery

From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection

Identification of Optimized Peptide Nucleic Acid (PNA) Designs for Nuclease-Free Gene Editing in Sickle Cell Disease Hematopoietic Stem and Progenitor Cells (HSPCs)

Systemic delivery of blood-brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue

Abstract 755: Fas Ligand- and Nitric Oxide-Releasing Stent

Next generation triplex-forming PNAs for site-specific genome editing of the F508del CFTR mutation

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