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Regioselective, Diastereoselective, and Enantioselective Lithiation−Substitution Sequences: Reaction Pathways and Synthetic Applications

Accounts of chemical research, 1996-11, Vol.29 (11), p.552-560

1996

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Efficient Synthesis of (2S,3S)-2-Ethyl-3-methylvaleramide Using (1S,2S)-Pseudoephedrine as a Chiral Auxiliary

Organic process research & development, 2009-05, Vol.13 (3), p.463-467

2009

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Pathways for Stereoinformation Transfer: Enhanced Enantioselectivity via Diastereomeric Recycling of Organolithium/(−)-Sparteine Complexes

Journal of organic chemistry, 1996-08, Vol.61 (17), p.5718-5719

1996

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Directed lithiations: the effect of varying directing group orientation on competitive efficiencies for a series of tertiary amide, secondary amide, and alkoxide directed ortho lithiations

Journal of the American Chemical Society, 1993-11, Vol.115 (23), p.10628-10636

1993

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Chiral Organolithium Complexes: The Effect of Ligand Structure on the Enantioselective Deprotonation of Boc-Pyrrolidine

Journal of organic chemistry, 1995-12, Vol.60 (25), p.8148-8154

1995

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Complex-Induced Proximity Effects: Evidence for a Prelithiation Complex and a Rate-Determining Deprotonation in the Asymmetric Lithiation of Boc-Pyrrolidine by an i-PrLi/(-)-Sparteine Complex

Journal of organic chemistry, 1995-11, Vol.60 (22), p.7092-7093

1995

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Pilot Plant Preparation of an αvβ3 Integrin Antagonist. Part 1. Process Research and Development of a (S)-β-Amino Acid Ester Intermediate: Synthesis via a Scalable, Diastereoselective Imino-Reformatsky Reaction

Organic process research & development, 2004-01, Vol.8 (1), p.51-61

2004

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Chiral Organolithium Complexes: The Structure of β-Lithiated β-Phenylcarboxamides and the Mechanism of Asymmetric Substitution in the Presence of (−)-Sparteine

Journal of the American Chemical Society, 1996-11, Vol.118 (46), p.11391-11398

1996

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Synthetic Applications of the β-Lithiation of β-Aryl Secondary Amides: Diastereoselective and Enantioselective Substitutions

Journal of organic chemistry, 1996-07, Vol.61 (14), p.4542-4554

1996

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Enantioselective deprotonation: the structure and reactivity of an unsymmetrically complexed isopropyllithium/sparteine/Et2O dimer

Journal of the American Chemical Society, 1992-07, Vol.114 (14), p.5872-5873

1992

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Is halogen-lithium exchange intramolecularly competitive with removal of an acidic hydrogen? Reinvestigation of a recent claim

Journal of the American Chemical Society, 1991-10, Vol.113 (21), p.7984-7987

1991

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Pathways for Stereoinformation Transfer: Enhanced Enantioselectivity via Diastereomeric Recycling of Organolithium/(−)-Sparteine Complexes

Journal of organic chemistry, 1997-03, Vol.62 (6), p.1908-1908

1997

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Selectivities in reactions of organolithium reagents with aryl bromides which bear proton-donating groups

Journal of organic chemistry, 1993-12, Vol.58 (26), p.7330-7335

1993

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Chiral Organolithium Complexes: The Effect of Ligand Structure on the Enantioselective Deprotonation of Boc-Pyrrolidine

Journal of organic chemistry, 1996-07, Vol.61 (15), p.5190-5190

1996

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Pilot-Plant Preparation of an α v β 3 Integrin Antagonist: Process Development of a Carbonyldiimidazole Peptide Coupling

Organic process research & development, 2009-01, Vol.13 (1), p.60-63

2009

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Metalation of cyclopropane rings: a novel trilithiation of a dicyclopropylcarbinol

Journal of organic chemistry, 1991-01, Vol.56 (2), p.853-856

1991

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Pilot Plant Preparation of an α v β 3 Integrin Antagonist. Part 1. Process Research and Development of a ( S )-β-Amino Acid Ester Intermediate: Synthesis via a Scalable, Diastereoselective Imino-Reformatsky Reaction

Organic process research & development, 2004-01, Vol.8 (1), p.51-61

2004

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Pilot-Plant Preparation of an αvβ3 Integrin Antagonist: Process Development of a Carbonyldiimidazole Peptide Coupling

Organic process research & development, 2009-01, Vol.13 (1), p.60-63

2009

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Metalation of cyclopropane rings : a novel trilithiation of a biscyclopropyl carbinol

Journal of organic chemistry, 1991-01, Vol.56 (2), p.853-856

1991

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Farm Injuries in Dane County, Wisconsin: An Epidemiological Study

Archives of environmental health, 1961-08, Vol.3 (2), p.201-208

1961

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Survival of the Enveloped Virus Phi6 in Droplets as a Function of Relative Humidity, Absolute Humidity, and Temperature

Applied and environmental microbiology, 2018-06, Vol.84 (12), p.e00551-18

2018

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Spectral Energy Distributions and Multiwavelength Selection of Type 1 Quasars

The Astrophysical journal. Supplement series, 2006-10, Vol.166 (2), p.470-497

2006

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Regioselective, Diastereoselective, and Enantioselective Lithiation−Substitution Sequences: Reaction Pathways and Synthetic Applications

Efficient Synthesis of (2S,3S)-2-Ethyl-3-methylvaleramide Using (1S,2S)-Pseudoephedrine as a Chiral Auxiliary

Pathways for Stereoinformation Transfer: Enhanced Enantioselectivity via Diastereomeric Recycling of Organolithium/(−)-Sparteine Complexes

Directed lithiations: the effect of varying directing group orientation on competitive efficiencies for a series of tertiary amide, secondary amide, and alkoxide directed ortho lithiations

Chiral Organolithium Complexes: The Effect of Ligand Structure on the Enantioselective Deprotonation of Boc-Pyrrolidine

Complex-Induced Proximity Effects: Evidence for a Prelithiation Complex and a Rate-Determining Deprotonation in the Asymmetric Lithiation of Boc-Pyrrolidine by an i-PrLi/(-)-Sparteine Complex

Pilot Plant Preparation of an αvβ3 Integrin Antagonist. Part 1. Process Research and Development of a (S)-β-Amino Acid Ester Intermediate: Synthesis via a Scalable, Diastereoselective Imino-Reformatsky Reaction

Pilot-Plant Preparation of an αvβ3 Integrin Antagonist. Part 3. Process Research and Development of a Diisopropylcarbodiimide and Catalytic 1-Hydroxybenzotriazole Peptide Coupling

Chiral Organolithium Complexes: The Structure of β-Lithiated β-Phenylcarboxamides and the Mechanism of Asymmetric Substitution in the Presence of (−)-Sparteine

Synthetic Applications of the β-Lithiation of β-Aryl Secondary Amides: Diastereoselective and Enantioselective Substitutions

Enantioselective deprotonation: the structure and reactivity of an unsymmetrically complexed isopropyllithium/sparteine/Et2O dimer

Is halogen-lithium exchange intramolecularly competitive with removal of an acidic hydrogen? Reinvestigation of a recent claim

Pathways for Stereoinformation Transfer: Enhanced Enantioselectivity via Diastereomeric Recycling of Organolithium/(−)-Sparteine Complexes

Selectivities in reactions of organolithium reagents with aryl bromides which bear proton-donating groups

Chiral Organolithium Complexes: The Effect of Ligand Structure on the Enantioselective Deprotonation of Boc-Pyrrolidine

Pilot-Plant Preparation of an α v β 3 Integrin Antagonist: Process Development of a Carbonyldiimidazole Peptide Coupling

Metalation of cyclopropane rings: a novel trilithiation of a dicyclopropylcarbinol

Pilot-Plant Preparation of an α v β 3 Integrin Antagonist. Part 3. Process Research and Development of a Diisopropylcarbodiimide and Catalytic 1-Hydroxybenzotriazole Peptide Coupling

Pilot Plant Preparation of an α v β 3 Integrin Antagonist. Part 1. Process Research and Development of a ( S )-β-Amino Acid Ester Intermediate: Synthesis via a Scalable, Diastereoselective Imino-Reformatsky Reaction

Pilot-Plant Preparation of an αvβ3 Integrin Antagonist: Process Development of a Carbonyldiimidazole Peptide Coupling

Metalation of cyclopropane rings : a novel trilithiation of a biscyclopropyl carbinol

Farm Injuries in Dane County, Wisconsin: An Epidemiological Study

Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies

Survival of the Enveloped Virus Phi6 in Droplets as a Function of Relative Humidity, Absolute Humidity, and Temperature

Spectral Energy Distributions and Multiwavelength Selection of Type 1 Quasars

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