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MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (21), p.5913-5924

2017

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Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration

British journal of cancer, 2020-03, Vol.122 (6), p.895-903

2020

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Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells

British journal of cancer, 2020-01, Vol.122 (1), p.72-81

2020

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Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging

Scientific reports, 2017-08, Vol.7 (1), p.8215-9, Article 8215

2017

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Targeting DNA Repair Defects for Precision Medicine in Prostate Cancer

Current oncology reports, 2019-05, Vol.21 (5), p.42-10, Article 42

2019

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Association of cystic fibrosis genetic modifiers with congenital bilateral absence of the vas deferens

Fertility and sterility, 2010-11, Vol.94 (6), p.2122-2127

2010

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Complete ascertainment of intragenic copy number mutations (CNMs) in the CFTR gene and its implications for CNM formation at other autosomal loci

Human mutation, 2010-04, Vol.31 (4), p.421-428

2010

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Abstract 444: Monocarboxylate transporter 1 inhibition with AZD3965 increases cancer cell dependence on bioenergetic metabolism predicating combination therapy with mitochondrial inhibitors

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.444-444

2017

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Different CFTR mutational spectrum in alcoholic and idiopathic chronic pancreatitis?

Pancreas, 2004-05, Vol.28 (4), p.374-379

2004

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Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders - updated European recommendations

European journal of human genetics : EJHG, 2009-01, Vol.17 (1), p.51-65

2009

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Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders – updated European recommendations

European journal of human genetics : EJHG, 2008-08, Vol.17 (1), p.51-65

2008

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Adenosine Triphosphate-Binding Cassette Superfamily Transporter Gene Expression in Severe Male Infertility

Biology of reproduction, 2001-08, Vol.65 (2), p.394-400

2001

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Assessing the residual CFTR gene expression in human nasal epithelium cells bearing CFTR splicing mutations causing cystic fibrosis

European journal of human genetics : EJHG, 2014-06, Vol.22 (6), p.784-791

2014

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New type of disease causing mutations: the example of the composite exonic regulatory elements of splicing in CFTR exon 12

Human molecular genetics, 2003-05, Vol.12 (10), p.1111-1120

2003

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Independent contribution of common CFTR variants to chronic pancreatitis

Pancreas, 2010-03, Vol.39 (2), p.209-215

2010

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GUSB and ATP2B4 are suitable reference genes for CFTR gene expression data normalization in nasal epithelium cells

Journal of cystic fibrosis, 2012-09, Vol.11 (5), p.398-404

2012

Volltextzugriff (PDF)

Abstract 4108: Longitudinal diffusion-weighted MRI assessment of NRAS mutant melanoma response to dual RAF-MEK inhibition reveals differences associated with collagen deposition

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4108-4108

2018

Volltextzugriff (PDF)

Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens

The New England journal of medicine, 1995-06, Vol.332 (22), p.1475-1480

1995

Volltextzugriff (PDF)

Optimizing strategies for CFTR molecular testing

Journal of cystic fibrosis, 2011-03, Vol.10 (2), p.143-144

2011

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Heterogeneity for mutations in the CFTR gene and clinical correlations in patients with congenital absence of the vas deferens

Human reproduction (Oxford), 2000-07, Vol.15 (7), p.1476-1483

2000

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Common CFTR haplotypes and susceptibility to chronic pancreatitis and congenital bilateral absence of the vas deferens

Human mutation, 2011-08, Vol.32 (8), p.912-920

2011

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Spectrum of Mutations in the CFTR Gene in Cystic Fibrosis Patients of Spanish Ancestry

Annals of human genetics, 2007-03, Vol.71 (2), p.194-201

2007

Volltextzugriff (PDF)

MCT1 inhibitor AZD3965 increases mitochondrial metabolism, facilitating combination therapy and non-invasive magnetic resonance spectroscopy

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (21), p.5913-5924

2017

Volltextzugriff (PDF)

Detection of a cystic fibrosis modifier locus for meconium ileus on human chromosome 19q13

Nature genetics, 1999-06, Vol.22 (2), p.128-129

1999

Volltextzugriff (PDF)

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MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy

Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration

Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells

Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging

Targeting DNA Repair Defects for Precision Medicine in Prostate Cancer

Association of cystic fibrosis genetic modifiers with congenital bilateral absence of the vas deferens

Complete ascertainment of intragenic copy number mutations (CNMs) in the CFTR gene and its implications for CNM formation at other autosomal loci

Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors

Abstract 444: Monocarboxylate transporter 1 inhibition with AZD3965 increases cancer cell dependence on bioenergetic metabolism predicating combination therapy with mitochondrial inhibitors

Different CFTR mutational spectrum in alcoholic and idiopathic chronic pancreatitis?

Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders - updated European recommendations

Best practice guidelines for molecular genetic diagnosis of cystic fibrosis and CFTR-related disorders – updated European recommendations

Adenosine Triphosphate-Binding Cassette Superfamily Transporter Gene Expression in Severe Male Infertility

Assessing the residual CFTR gene expression in human nasal epithelium cells bearing CFTR splicing mutations causing cystic fibrosis

New type of disease causing mutations: the example of the composite exonic regulatory elements of splicing in CFTR exon 12

Independent contribution of common CFTR variants to chronic pancreatitis

GUSB and ATP2B4 are suitable reference genes for CFTR gene expression data normalization in nasal epithelium cells

Abstract 4108: Longitudinal diffusion-weighted MRI assessment of NRAS mutant melanoma response to dual RAF-MEK inhibition reveals differences associated with collagen deposition

Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens

Optimizing strategies for CFTR molecular testing

Heterogeneity for mutations in the CFTR gene and clinical correlations in patients with congenital absence of the vas deferens

Common CFTR haplotypes and susceptibility to chronic pancreatitis and congenital bilateral absence of the vas deferens

Spectrum of Mutations in the CFTR Gene in Cystic Fibrosis Patients of Spanish Ancestry

MCT1 inhibitor AZD3965 increases mitochondrial metabolism, facilitating combination therapy and non-invasive magnetic resonance spectroscopy

Detection of a cystic fibrosis modifier locus for meconium ileus on human chromosome 19q13

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