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Cellular and epigenetic drivers of stem cell ageing

Nature reviews. Molecular cell biology, 2018-09, Vol.19 (9), p.594-610

2018

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The Role of Telomeres in Stem Cells and Cancer

Cell, 2013-01, Vol.152 (3), p.390-393

2013

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Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer

Cell stem cell, 2015-06, Vol.16 (6), p.601-612

2015

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SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling

Cell stem cell, 2016-04, Vol.18 (4), p.495-507

2016

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A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

Cell, 2012-03, Vol.148 (5), p.1001-1014

2012

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Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors

Cancer cell, 2013-01, Vol.23 (1), p.93-106

2013

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Granulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cells

Haematologica (Roma), 2021-06, Vol.106 (6), p.1516-1518

2021

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Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation

The Journal of experimental medicine, 2019-01, Vol.216 (1), p.152-175

2019

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Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

Nature medicine, 2007-06, Vol.13 (6), p.742-747

2007

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Lentiviral in situ targeting of stem cells in unperturbed intestinal epithelium

BMC biology, 2023-01, Vol.21 (1), p.6-6, Article 6

2023

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Evolution, mechanism and limits of dietary restriction induced health benefits & longevity

Redox biology, 2023-07, Vol.63, p.102725-102725, Article 102725

2023

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Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction

Cell reports (Cambridge), 2020-04, Vol.31 (4), p.107565-107565, Article 107565

2020

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Aging in the lympho-hematopoietic stem cell compartment

Trends in immunology, 2009-07, Vol.30 (7), p.360-365

2009

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Quiescence: Good and Bad of Stem Cell Aging

Trends in cell biology, 2019-08, Vol.29 (8), p.672-685

2019

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Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Prehypertension: Relation to Endothelial Dysfunction

Hypertension (Dallas, Tex. 1979), 2010-06, Vol.55 (6), p.1389-1397

2010

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Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing

Nature cell biology, 2019-06, Vol.21 (6), p.791-792

2019

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Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways

Nature communications, 2015-04, Vol.6 (1), p.6808-6808, Article 6808

2015

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Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response

EMBO reports, 2021-08, Vol.22 (8), p.e52905-n/a

2021

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ROS induced DNA damage and checkpoint responses: Influences on aging?

Cell cycle (Georgetown, Tex.), 2010-10, Vol.9 (20), p.4058-4060

2010

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Telomerase gene mutations are associated with cirrhosis formation

Hepatology (Baltimore, Md.), 2011-05, Vol.53 (5), p.1608-1617

2011

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Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor

Oncogene, 2020-02, Vol.39 (7), p.1445-1465

2020

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Author Correction: Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction

Nature cell biology, 2021-03, Vol.23 (3), p.292-292

2021

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DNA damage checkpoints in stem cells, ageing and cancer

Nature reviews. Molecular cell biology, 2012-09, Vol.13 (9), p.579-590

2012

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Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

The FASEB journal, 2002-07, Vol.16 (9), p.935-942

2002

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p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

Nature genetics, 2009-10, Vol.41 (10), p.1138-1143

2009

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Cellular and epigenetic drivers of stem cell ageing

The Role of Telomeres in Stem Cells and Cancer

Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer

SIRT6 Controls Hematopoietic Stem Cell Homeostasis through Epigenetic Regulation of Wnt Signaling

A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors

Granulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cells

Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

Lentiviral in situ targeting of stem cells in unperturbed intestinal epithelium

Evolution, mechanism and limits of dietary restriction induced health benefits & longevity

Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction

Aging in the lympho-hematopoietic stem cell compartment

Quiescence: Good and Bad of Stem Cell Aging

Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Prehypertension: Relation to Endothelial Dysfunction

Author Correction: Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing

Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways

Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response

ROS induced DNA damage and checkpoint responses: Influences on aging?

Telomerase gene mutations are associated with cirrhosis formation

Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor

Author Correction: Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction

DNA damage checkpoints in stem cells, ageing and cancer

Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

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