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Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view

European journal of medicinal chemistry, 2017-07, Vol.134, p.159-184

2017

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Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials

Bioorganic chemistry, 2018-12, Vol.81, p.119-126

2018

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An insight into medicinal attributes of dithiocarbamates: Bird’s eye view

Bioorganic chemistry, 2020-12, Vol.105, p.104346-104346, Article 104346

2020

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The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies

Neuroscience and biobehavioral reviews, 2010-07, Vol.34 (8), p.1307-1350

2010

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Aconitum and Delphinium alkaloids of curare-like activity. QSAR analysis and molecular docking of alkaloids into AChBP

European journal of medicinal chemistry, 2010-09, Vol.45 (9), p.3885-3894

2010

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Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug

Experimental and molecular pathology, 2016-06, Vol.100 (3), p.522-531

2016

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Penehyclidine hydrochloride decreases pulmonary microvascular permeability by upregulating beta arrestins in a murine cecal ligation and puncture model

The Journal of surgical research, 2015-01, Vol.193 (1), p.391-398

2015

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Similarity in drugs: reflections on analogue design

Drug discovery today, 2006-04, Vol.11 (7), p.348-354

Wermuth, Camille G.

2006

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Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states

Biochimica et biophysica acta, 2010-06, Vol.1798 (6), p.1153-1163

2010

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3D-QSAR study of 8-azabicyclo[3.2.1] octane analogs antagonists of cholinergic receptor

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (11), p.3108-3112

2009

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Alkyne–quinuclidine derivatives as potent and selective muscarinic antagonists for the treatment of COPD

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2675-2678

2008

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An efficient approach to the asymmetric total synthesis of (–)-anisodine

European journal of medicinal chemistry, 2006-03, Vol.41 (3), p.397-400

2006

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The effect of agrin and laminin on acetylcholine receptor dynamics in vitro

Developmental biology, 2005-12, Vol.288 (1), p.248-258

2005

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Liquid chromatography–tandem electrospray mass spectrometry method for determination of serial chiral novel anticholinergic compounds of phencynonate in rat plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007-08, Vol.855 (2), p.180-185

2007

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The 1.1 å crystal structure of the neuronal acetylcholine receptor antagonist, α-conotoxin PnIA from Conus pennaceus

Structure (London), 1996-04, Vol.4 (4), p.417-423

1996

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Simultaneous determination of enantiomers of structurally related anticholinergic analogs in human serum by liquid chromatography–electrospray ionization mass spectrometry with on-line sample cleanup

Journal of chromatography. B, Biomedical sciences and applications, 2001-10, Vol.762 (2), p.181-192

2001

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Novel neurotoxins from Taiwan banded krait ( Bungarus multicinctus) venom: purification, characterization and gene organization

Toxicon (Oxford), 2003-09, Vol.42 (3), p.323-330

2003

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Stability study of a new antidote drug combination (Atropine–HI-6–Prodiazepam) for treatment of organophosphate poisoning

European journal of pharmaceutical sciences, 2000, Vol.9 (3), p.259-263

2000

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Pharmacological Characterization of the Discriminative Stimulus Effects of Clenbuterol in Rats

Pharmacology, biochemistry and behavior, 1997-11, Vol.58 (3), p.813-818

O’DONNELL, James M

1997

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6-Hydroxycatecholine, a Choline-Mimicking Analogue of the Selective Neurotoxin, 6-Hydroxydopamine

Biochemical and biophysical research communications, 1996-11, Vol.228 (1), p.187-192

1996

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The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

Bioorganic chemistry, 2019-04, Vol.85, p.128-139

2019

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Contribution of cholinergic interneurons to striatal pathophysiology in Parkinson's disease

Neurochemistry international, 2019-06, Vol.126, p.1-10

2019

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Effect of olive leaf phytochemicals on the anti-acetylcholinesterase, anti-cyclooxygenase-2 and ferric reducing antioxidant capacity

Food chemistry, 2024-06, Vol.444, p.138516-138516, Article 138516

2024

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Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

Biochemical pharmacology, 2011-10, Vol.82 (8), p.915-930

2011

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Exploring the impact of novel thiazole-pyrazole fused benzo-coumarin derivatives on human serum albumin: Synthesis, photophysical properties, anti-cholinergic activity, and interaction studies

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2024-03, Vol.308, p.123669, Article 123669

2024

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Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view

Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors – Their antidiabetic, anticholinergic and antibacterial potentials

An insight into medicinal attributes of dithiocarbamates: Bird’s eye view

The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies

Aconitum and Delphinium alkaloids of curare-like activity. QSAR analysis and molecular docking of alkaloids into AChBP

Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug

Penehyclidine hydrochloride decreases pulmonary microvascular permeability by upregulating beta arrestins in a murine cecal ligation and puncture model

Similarity in drugs: reflections on analogue design

Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states

3D-QSAR study of 8-azabicyclo[3.2.1] octane analogs antagonists of cholinergic receptor

Alkyne–quinuclidine derivatives as potent and selective muscarinic antagonists for the treatment of COPD

An efficient approach to the asymmetric total synthesis of (–)-anisodine

The effect of agrin and laminin on acetylcholine receptor dynamics in vitro

Liquid chromatography–tandem electrospray mass spectrometry method for determination of serial chiral novel anticholinergic compounds of phencynonate in rat plasma

The 1.1 å crystal structure of the neuronal acetylcholine receptor antagonist, α-conotoxin PnIA from Conus pennaceus

Simultaneous determination of enantiomers of structurally related anticholinergic analogs in human serum by liquid chromatography–electrospray ionization mass spectrometry with on-line sample cleanup

Novel neurotoxins from Taiwan banded krait ( Bungarus multicinctus) venom: purification, characterization and gene organization

Stability study of a new antidote drug combination (Atropine–HI-6–Prodiazepam) for treatment of organophosphate poisoning

Pharmacological Characterization of the Discriminative Stimulus Effects of Clenbuterol in Rats

6-Hydroxycatecholine, a Choline-Mimicking Analogue of the Selective Neurotoxin, 6-Hydroxydopamine

The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products

Contribution of cholinergic interneurons to striatal pathophysiology in Parkinson's disease

Effect of olive leaf phytochemicals on the anti-acetylcholinesterase, anti-cyclooxygenase-2 and ferric reducing antioxidant capacity

Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

Exploring the impact of novel thiazole-pyrazole fused benzo-coumarin derivatives on human serum albumin: Synthesis, photophysical properties, anti-cholinergic activity, and interaction studies

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