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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex

Nature communications, 2017-05, Vol.8 (1), p.15522-15522, Article 15522

2017

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An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors

Journal of the American Chemical Society, 2010-12, Vol.132 (47), p.16962-16976

2010

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Total Synthesis and Stereochemical Reassignment of (+)-Neopeltolide

Angewandte Chemie (International ed.), 2007-01, Vol.46 (48), p.9211-9214

2007

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Synthesis of a 35-Member Stereoisomer Library of Bistramide A: Evaluation of Effects on actin State, Cell Cycle and Tumor Cell Growth

Journal of organic chemistry, 2009-03, Vol.74 (5), p.1897-1916

2009

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Stereocontrolled [4+2]-Annulation Accessing Dihydropyrans: Synthesis of the C1a-C10 Fragment of Kendomycin

Organic letters, 2005-04, Vol.7 (8), p.1529-1532

2005

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Regioselective Intramolecular Dipolar Cycloaddition of Azides and Unsymmetrical Alkynes

Organic letters, 2010-01, Vol.12 (2), p.336-339

2010

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Total Synthesis of (−)-Kendomycin

Organic letters, 2008-09, Vol.10 (17), p.3813-3816

2008

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Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries

Journal of organic chemistry, 2012-09, Vol.77 (17), p.7187-7211

2012

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Diversity-Oriented Synthesis of 13- to 18-Membered Macrolactams via Ring-Closing Metathesis

Journal of organic chemistry, 2011-10, Vol.76 (19), p.8042-8048

2011

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Total Synthesis of Bistramide A

Organic letters, 2007-01, Vol.9 (2), p.327-330

2007

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Synthesis and [4 + 2]-Annulation of Enantioenriched (Z)-Crotylsilanes: Preparation of the C1−C13 Fragment of Bistramide A

Organic letters, 2005-07, Vol.7 (15), p.3231-3234

2005

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Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via SNAr Cycloetherification

ACS combinatorial science, 2011-07, Vol.13 (4), p.365-374

2011

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Mild Reductive Opening of Aryl Pyranosides Promoted by Scandium(III) Triflate

Journal of the American Chemical Society, 2007-01, Vol.129 (1), p.38-39

2007

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Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C‑Glycosides

Journal of organic chemistry, 2013-06, Vol.78 (11), p.5160-5171

2013

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A Convenient Multigram Synthesis of Highly Enantioenriched Methyl 3-Silylglycidates

Journal of organic chemistry, 2006-04, Vol.71 (9), p.3639-3642

2006

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Stereocontrolled [4+2]-Annulation Accessing Dihydropyrans: Synthesis of the C1a-C10 Fragment of Kendomycin

Organic letters, 2007-07, Vol.9 (14), p.2753-2753

2007

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Abstract B37: Development of inhibitors of the activated form of KRAS G12C

Molecular cancer research, 2020-05, Vol.18 (5_Supplement), p.B37-B37

2020

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Total Synthesis and Stereochemical Reassignment of (+)-Neopeltolide

Angewandte Chemie, 2007-12, Vol.119 (48), p.9371-9374

2007

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Se,Se′-Diphenyl carbonodiselenoate: preparation and characterization of its molecular structure and thermal reactivity

Chemical communications (Cambridge, England), 2001-01 (15), p.1390-1391

2001

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Ruthenium(III) Chloride (RuCl3)

Synlett, 2007-07, Vol.2007 (12), p.1974-1975

Lowe, Jason T.

2007

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Abstract 5564: Total synthesis of 6-deoxypladienolide D and assessment of splicing inhibitory activity in a mutant SF3B1 cancer cell line

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.5564-5564

2015

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Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via S N Ar Cycloetherification

ACS combinatorial science, 2011-07, Vol.13 (4), p.365-374

2011

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Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via S sub(N)Ar Cycloetherification

ACS combinatorial science, 2011-07, Vol.13 (4), p.365-374-365-374

2011

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Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification

ACS combinatorial science, 2011-07, Vol.13 (4), p.365-374

2011

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1 – 25 von 519

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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex

An Aldol-Based Build/Couple/Pair Strategy for the Synthesis of Medium- and Large-Sized Rings: Discovery of Macrocyclic Histone Deacetylase Inhibitors

Total Synthesis and Stereochemical Reassignment of (+)-Neopeltolide

Synthesis of a 35-Member Stereoisomer Library of Bistramide A: Evaluation of Effects on actin State, Cell Cycle and Tumor Cell Growth

Stereocontrolled [4+2]-Annulation Accessing Dihydropyrans: Synthesis of the C1a-C10 Fragment of Kendomycin

Regioselective Intramolecular Dipolar Cycloaddition of Azides and Unsymmetrical Alkynes

Total Synthesis of (−)-Kendomycin

Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries

Diversity-Oriented Synthesis of 13- to 18-Membered Macrolactams via Ring-Closing Metathesis

Total Synthesis of 6‑Deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 Cancer Cell Line

Total Synthesis of Bistramide A

Synthesis and [4 + 2]-Annulation of Enantioenriched (Z)-Crotylsilanes: Preparation of the C1−C13 Fragment of Bistramide A

Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via SNAr Cycloetherification

Mild Reductive Opening of Aryl Pyranosides Promoted by Scandium(III) Triflate

Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C‑Glycosides

A Convenient Multigram Synthesis of Highly Enantioenriched Methyl 3-Silylglycidates

Stereocontrolled [4+2]-Annulation Accessing Dihydropyrans: Synthesis of the C1a-C10 Fragment of Kendomycin

Abstract B37: Development of inhibitors of the activated form of KRAS G12C

Total Synthesis and Stereochemical Reassignment of (+)-Neopeltolide

Se,Se′-Diphenyl carbonodiselenoate: preparation and characterization of its molecular structure and thermal reactivity

Ruthenium(III) Chloride (RuCl3)

Abstract 5564: Total synthesis of 6-deoxypladienolide D and assessment of splicing inhibitory activity in a mutant SF3B1 cancer cell line

Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via S N Ar Cycloetherification

Synthesis of a Stereochemically Diverse Library of Medium-Sized Lactams and Sultams via S sub(N)Ar Cycloetherification

Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification

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