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Migraine therapeutics differentially modulate the CGRP pathway

Cephalalgia, 2021-04, Vol.41 (5), p.499-514

2021

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Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

The Journal of neuroscience, 2017-07, Vol.37 (30), p.7149-7163

2017

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Response to letter to the Editor: Assessing migraine therapeutics

Cephalalgia, 2021-11, Vol.41 (13), p.1404-1406

2021

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Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Scientific reports, 2023-10, Vol.13 (1), p.16699-16699, Article 16699

2023

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Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine

Brain (London, England : 1878), 2022-08, Vol.145 (8), p.2894-2909

2022

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Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

Journal of headache and pain, 2018-08, Vol.19 (1), p.66-66, Article 66

2018

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The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13471

2023

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Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

BMC research notes, 2023-11, Vol.16 (1), p.1-348, Article 348

2023

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Immunogenicity of biologic therapies for migraine: a review of current evidence

Journal of headache and pain, 2021-01, Vol.22 (1), p.3-8, Article 3

2021

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An in vivo accelerated developmental myelination model for testing promyelinating therapeutics

BMC neuroscience, 2022-05, Vol.23 (1), p.30-30, Article 30

2022

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Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.572

2024

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The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Cells (Basel, Switzerland), 2022-05, Vol.11 (11), p.1768

2022

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Commentary: Constipation caused by anti-calcitonin gene-related peptide migraine therapeutics explained by antagonism of calcitonin gene-related peptide's motor-stimulating and prosecretory function in the intestine

Frontiers in physiology, 2022-11, Vol.13, p.1067274-1067274

2022

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Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

Neurology international, 2023-04, Vol.15 (2), p.622-637

2023

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Crosstalk between bone metastatic cancer cells and sensory nerves in bone metastatic progression

Life science alliance, 2024-12, Vol.7 (12), p.e202302041

2024

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TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

Endocrinology (Philadelphia), 2008-03, Vol.149 (3), p.1038-1048

2008

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Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model

Cephalalgia, 2020-10, Vol.40 (11), p.1224-1239

2020

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Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Cephalalgia, 2020-06, Vol.40 (7), p.748-760

2020

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Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors

The Journal of neuroscience, 2017-11, Vol.37 (44), p.10587-10596

2017

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Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates

PloS one, 2008-04, Vol.3 (4), p.e1900

2008

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CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura

The Journal of neuroscience, 2019-07, Vol.39 (30), p.6001-6011

2019

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CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

Cephalalgia, 2019-12, Vol.39 (14), p.1762-1775

2019

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Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

Cephalalgia, 2020-03, Vol.40 (3), p.229-240

2020

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Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood-brain barrier

Pain (Amsterdam), 2020-05, Vol.161 (5), p.1037-1043

2020

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A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

The Journal of pharmacology and experimental therapeutics, 2021-12, Vol.379 (3), p.270-279

2021

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Migraine therapeutics differentially modulate the CGRP pathway

Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

Response to letter to the Editor: Assessing migraine therapeutics

Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine

Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

Immunogenicity of biologic therapies for migraine: a review of current evidence

An in vivo accelerated developmental myelination model for testing promyelinating therapeutics

Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab

The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Commentary: Constipation caused by anti-calcitonin gene-related peptide migraine therapeutics explained by antagonism of calcitonin gene-related peptide's motor-stimulating and prosecretory function in the intestine

Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

Crosstalk between bone metastatic cancer cells and sensory nerves in bone metastatic progression

TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors

Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates

CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura

CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood-brain barrier

A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

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