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Testing a Primary and a Secondary Endpoint in a Group Sequential Design

Biometrics, 2010-12, Vol.66 (4), p.1174-1184

2010

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Adaptive increase in sample size when interim results are promising: A practical guide with examples

Statistics in medicine, 2011-12, Vol.30 (28), p.3267-3284

2011

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Adaptive extensions of a two-stage group sequential procedure for testing primary and secondary endpoints (I): unknown correlation between the endpoints

Statistics in medicine, 2012-08, Vol.31 (19), p.2027-2040

2012

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The distance of the femoral neurovascular bundle from the hip joint: an intraoperative guide to reduce iatrogenic injury

Journal of orthopaedic surgery and research, 2018-06, Vol.13 (1), p.135-135, Article 135

2018

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Adaptive extensions of a two-stage group sequential procedure for testing primary and secondary endpoints (II): sample size re-estimation

Statistics in medicine, 2012-08, Vol.31 (19), p.2041-2054

2012

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Bifocal disruption to the extensor mechanism of the knee: A case report

Journal of Orthopaedic Reports, 2025-09, Vol.4 (3), p.100404, Article 100404

2025

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The potential role and rationale for treatment of heart failure with sodium–glucose co‐transporter 2 inhibitors

European journal of heart failure, 2017-11, Vol.19 (11), p.1390-1400

2017

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Pathophysiological Sex Differences in Heart Failure Progression After Acute Coronary Syndrome: Insights From the EXAMINE Trial

Journal of cardiac failure, 2024-06, Vol.30 (6), p.767-777

2024

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Repeated confidence intervals for adaptive group sequential trials

Statistics in medicine, 2007-12, Vol.26 (30), p.5422-5433

2007

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Optimal promising zone designs

Biometrical journal, 2019-09, Vol.61 (5), p.1175-1186

2019

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A Gatekeeping Procedure to Test a Primary and a Secondary Endpoint in a Group Sequential Design with Multiple Interim Looks

Biometrics, 2018-03, Vol.74 (1), p.40-48

2018

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Serial Measurement of High-Sensitivity Troponin I and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus in the EXAMINE Trial (Examination of Cardiovascular Outcomes With Alogliptin Versus Standard of Care)

Circulation (New York, N.Y.), 2017-05, Vol.135 (20), p.1911-1921

2017

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External validation and extension of the TIMI risk score for heart failure in diabetes for patients with recent acute coronary syndrome: An analysis of the EXAMINE trial

Diabetes, obesity & metabolism, 2023-01, Vol.25 (1), p.229-237

2023

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Adaptive clinical trial designs with pre-specified rules for modifying the sample size: a different perspective

Statistics in medicine, 2013-04, Vol.32 (8), p.1276-1279

Mehta, Cyrus R.

2013

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Relationship of glycated haemoglobin and reported hypoglycaemia to cardiovascular outcomes in patients with type 2 diabetes and recent acute coronary syndrome events: The EXAMINE trial

Diabetes, obesity & metabolism, 2017-05, Vol.19 (5), p.664-671

2017

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Fasiglifam-Induced Liver Injury in Patients With Type 2 Diabetes: Results of a Randomized Controlled Cardiovascular Outcomes Safety Trial

Diabetes care, 2018-12, Vol.41 (12), p.2603-2609

2018

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Efficiency Considerations for Group Sequential Designs with Adaptive Unblinded Sample Size Re-assessment

Statistics in biosciences, 2018-08, Vol.10 (2), p.405-419

2018

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Exact Confidence Bounds Following Adaptive Group Sequential Tests

Biometrics, 2009-06, Vol.65 (2), p.539-546

2009

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Total cardiovascular events analysis of the EXAMINE trial in patients with type 2 diabetes and recent acute coronary syndrome

Clinical cardiology (Mahwah, N.J.), 2018-08, Vol.41 (8), p.1022-1027

2018

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Ischemic cardiac outcomes and hospitalizations according to prior macrovascular disease status in patients with type 2 diabetes and recent acute coronary syndrome from the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial

The American heart journal, 2016-05, Vol.175, p.18-27

2016

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Authors' response to "Comment on adaptive increase in sample size when interim results are promising"

Statistics in medicine, 2011-12, Vol.30 (28), p.3302-3303

2011

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Adaptive, group sequential and decision theoretic approaches to sample size determination

Statistics in medicine, 2006-10, Vol.25 (19), p.3250-3269

2006

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Exact logistic regression: Theory and examples

Statistics in medicine, 1995-10, Vol.14 (19), p.2143-2160

1995

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Small-sample comparisons of confidence intervals for the difference of two independent binomial proportions

Computational statistics & data analysis, 2007-08, Vol.51 (12), p.5791-5799

2007

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Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial

The Lancet (British edition), 2015-05, Vol.385 (9982), p.2067-2076

2015

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Testing a Primary and a Secondary Endpoint in a Group Sequential Design

Adaptive increase in sample size when interim results are promising: A practical guide with examples

Adaptive extensions of a two-stage group sequential procedure for testing primary and secondary endpoints (I): unknown correlation between the endpoints

The distance of the femoral neurovascular bundle from the hip joint: an intraoperative guide to reduce iatrogenic injury

Adaptive extensions of a two-stage group sequential procedure for testing primary and secondary endpoints (II): sample size re-estimation

Bifocal disruption to the extensor mechanism of the knee: A case report

The potential role and rationale for treatment of heart failure with sodium–glucose co‐transporter 2 inhibitors

Pathophysiological Sex Differences in Heart Failure Progression After Acute Coronary Syndrome: Insights From the EXAMINE Trial

Repeated confidence intervals for adaptive group sequential trials

Optimal promising zone designs

A Gatekeeping Procedure to Test a Primary and a Secondary Endpoint in a Group Sequential Design with Multiple Interim Looks

Serial Measurement of High-Sensitivity Troponin I and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus in the EXAMINE Trial (Examination of Cardiovascular Outcomes With Alogliptin Versus Standard of Care)

External validation and extension of the TIMI risk score for heart failure in diabetes for patients with recent acute coronary syndrome: An analysis of the EXAMINE trial

Adaptive clinical trial designs with pre-specified rules for modifying the sample size: a different perspective

Relationship of glycated haemoglobin and reported hypoglycaemia to cardiovascular outcomes in patients with type 2 diabetes and recent acute coronary syndrome events: The EXAMINE trial

Fasiglifam-Induced Liver Injury in Patients With Type 2 Diabetes: Results of a Randomized Controlled Cardiovascular Outcomes Safety Trial

Efficiency Considerations for Group Sequential Designs with Adaptive Unblinded Sample Size Re-assessment

Exact Confidence Bounds Following Adaptive Group Sequential Tests

Total cardiovascular events analysis of the EXAMINE trial in patients with type 2 diabetes and recent acute coronary syndrome

Ischemic cardiac outcomes and hospitalizations according to prior macrovascular disease status in patients with type 2 diabetes and recent acute coronary syndrome from the Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care trial

Authors' response to "Comment on adaptive increase in sample size when interim results are promising"

Adaptive, group sequential and decision theoretic approaches to sample size determination

Exact logistic regression: Theory and examples

Small-sample comparisons of confidence intervals for the difference of two independent binomial proportions

Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial

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