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Maraviroc: a review of its use in HIV infection and beyond

Drug design, development and therapy, 2015-01, Vol.9 (default), p.5447-5468

2015

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A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action

European journal of pharmaceutical sciences, 2013-02, Vol.48 (3), p.406-415

2013

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Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s

Scientific reports, 2019-03, Vol.9 (1), p.4828, Article 4828

2019

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Chemokine receptor CCR5 antagonist maraviroc: medicinal chemistry and clinical applications

Current topics in medicinal chemistry, 2014-09, Vol.14 (13), p.1504

2014

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How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?

Biochemical journal, 2017-05, Vol.474 (10), p.1559-1577

2017

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Asymmetric Synthesis of (−)-Brevipolide H through Cyclopropanation of the α,β-Unsaturated Ketone

Organic letters, 2014-10, Vol.16 (20), p.5328-5331

2014

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Incompatible Natures of the HIV-1 Envelope in Resistance to the CCR5 Antagonist Cenicriviroc and to Neutralizing Antibodies

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.437-450

2016

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Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists

Organic & biomolecular chemistry, 2015-01, Vol.13 (8), p.2407-2422

2015

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Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Immunity (Cambridge, Mass.), 2017-06, Vol.46 (6), p.1005-1017.e5

2017

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Targeting CCR5 as a Component of an HIV-1 Therapeutic Strategy

Frontiers in immunology, 2022-01, Vol.12, p.816515

2022

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The efficacy and safety of maraviroc addition to a stable antiretroviral regimen in subjects with suppressed plasma HIV-RNA is not influenced by age

AIDS research and human retroviruses, 2015-09, Vol.31 (9), p.893

2015

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Co-receptor signaling in the pathogenesis of neuroHIV

Retrovirology, 2021-08, Vol.18 (1), p.24-24, Article 24

2021

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Targeting chemokine receptors for HIV: past, present and future

Future medicinal chemistry, 2015-01, Vol.7 (17), p.2311-2315

Fricker, Simon P

2015

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Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES

Journal of controlled release, 2019-03, Vol.298, p.1-11

2019

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Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

AIDS (London), 2022-01, Vol.36 (1), p.11-18

2022

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A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands

British journal of pharmacology, 2014-07, Vol.171 (14), p.3364-3375

2014

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The applications of PCA in QSAR studies: A case study on CCR5 antagonists

Chemical biology & drug design, 2018-01, Vol.91 (1), p.137-152

2018

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Blockade of CCR5 receptor prevents M2 microglia phenotype in a microglia-glioma paradigm

Neurochemistry international, 2017-09, Vol.108, p.100-108

2017

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Filling the Gaps in Antagonist CCR5 Binding, a Retrospective and Perspective Analysis

Frontiers in immunology, 2022-01, Vol.13, p.826418-826418

2022

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CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

Molecules (Basel, Switzerland), 2019-02, Vol.24 (3), p.550

2019

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Rational Engineering of a Sub-Picomolar HIV-1 Blocker

Viruses, 2022-10, Vol.14 (11), p.2415

2022

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Maraviroc exposure is influenced by exogenous thyrotoxicosis

AIDS (London), 2021-03, Vol.35 (4), p.701-703

2021

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Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques

Journal of virology, 2018-09, Vol.92 (17)

2018

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Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics

Drug metabolism and disposition, 2019-09, Vol.47 (9), p.954-960

2019

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A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus

PLoS neglected tropical diseases, 2016-01, Vol.10 (1), p.e0004364-e0004364

2016

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Maraviroc: a review of its use in HIV infection and beyond

A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action

Activity and structural analysis of GRL-117C: a novel small molecule CCR5 inhibitor active against R5-tropic HIV-1s

Chemokine receptor CCR5 antagonist maraviroc: medicinal chemistry and clinical applications

How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?

Asymmetric Synthesis of (−)-Brevipolide H through Cyclopropanation of the α,β-Unsaturated Ketone

Incompatible Natures of the HIV-1 Envelope in Resistance to the CCR5 Antagonist Cenicriviroc and to Neutralizing Antibodies

Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Targeting CCR5 as a Component of an HIV-1 Therapeutic Strategy

The efficacy and safety of maraviroc addition to a stable antiretroviral regimen in subjects with suppressed plasma HIV-RNA is not influenced by age

Co-receptor signaling in the pathogenesis of neuroHIV

Targeting chemokine receptors for HIV: past, present and future

Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES

Clinical evidence for a lack of cross-resistance between temsavir and ibalizumab or maraviroc

A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands

The applications of PCA in QSAR studies: A case study on CCR5 antagonists

Blockade of CCR5 receptor prevents M2 microglia phenotype in a microglia-glioma paradigm

Filling the Gaps in Antagonist CCR5 Binding, a Retrospective and Perspective Analysis

CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

Rational Engineering of a Sub-Picomolar HIV-1 Blocker

Maraviroc exposure is influenced by exogenous thyrotoxicosis

Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques

Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics

A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus

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