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Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm

The AAPS journal, 2015-09, Vol.17 (5), p.1224-1236

2015

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Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

The AAPS journal, 2008-12, Vol.10 (4), p.516-525

2008

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Crystalline Nanosuspensions as Potential Toxicology and Clinical Oral Formulations for BCS II/IV Compounds

The AAPS journal, 2012-12, Vol.14 (4), p.677-687

2012

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Use of Preclinical Dog Studies and Absorption Modeling to Facilitate Late Stage Formulation Bridging for a BCS II Drug Candidate

AAPS PharmSciTech, 2014-02, Vol.15 (1), p.20-28

Kesisoglou, Filippos

2014

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Characteristics of the Human Upper Gastrointestinal Contents in the Fasted State Under Hypo- and A-chlorhydric Gastric Conditions Under Conditions of Typical Drug – Drug Interaction Studies

Pharmaceutical research, 2016-06, Vol.33 (6), p.1399-1412

2016

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Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

The AAPS journal, 2020-09, Vol.22 (6), p.123, Article 123

2020

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Physiologically Based Absorption Modeling of Salts of Weak Bases Based on Data in Hypochlorhydric and Achlorhydric Biorelevant Media

AAPS PharmSciTech, 2018-10, Vol.19 (7), p.2851-2858

2018

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Application of Absorption Modeling to Predict Bioequivalence Outcome of Two Batches of Etoricoxib Tablets

AAPS PharmSciTech, 2015-02, Vol.16 (1), p.76-84

2015

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Physiologically based Pharmacokinetic Models under the Prism of the Finite Absorption Time Concept

Pharmaceutical research, 2023-02, Vol.40 (2), p.419-429

2023

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PBPK Absorption Modeling: Establishing the In Vitro–In Vivo Link—Industry Perspective

The AAPS journal, 2019-01, Vol.21 (2), p.19-19, Article 19

2019

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Applications of Clinically Relevant Dissolution Testing: Workshop Summary Report

The AAPS journal, 2018-08, Vol.20 (6), p.93-93, Article 93

2018

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Physiologically Based Biopharmaceutics Modeling for Gefapixant IR Formulation Development and Defining the Bioequivalence Dissolution Safe Space

The AAPS journal, 2024-06, Vol.26 (4), p.69, Article 69

2024

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Dissolution and Translational Modeling Strategies Enabling Patient-Centric Drug Product Development: the M-CERSI Workshop Summary Report

The AAPS journal, 2018-05, Vol.20 (3), p.60-60, Article 60

2018

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Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models

The AAPS journal, 2021-06, Vol.23 (4), p.85-85, Article 85

2021

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Using Mechanistic Modeling Approaches to Support Bioequivalence Assessments for Oral Products

The AAPS journal, 2024-01, Vol.26 (1), p.19-19, Article 19

2024

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Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System

The AAPS journal, 2017-07, Vol.19 (4), p.989-1001

2017

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Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate

The AAPS journal, 2015-11, Vol.17 (6), p.1492-1500

2015

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Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report

The AAPS journal, 2019-02, Vol.21 (2), p.29-29, Article 29

2019

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An IQ Consortium Perspective on Connecting Dissolution Methods to In Vivo Performance: Analysis of an Industrial Database and Case Studies to Propose a Workflow

The AAPS journal, 2022-05, Vol.24 (3), p.49-49, Article 49

2022

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Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis

The AAPS journal, 2023-06, Vol.25 (4), p.60-60, Article 60

2023

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A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development

The AAPS journal, 2022-05, Vol.24 (3), p.61-61, Article 61

2022

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Approaches for Establishing Clinically Relevant Dissolution Specifications for Immediate Release Solid Oral Dosage Forms

The AAPS journal, 2017-11, Vol.19 (6), p.1537-1549

2017

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Correction to: Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products

The AAPS journal, 2020-12, Vol.23 (1), p.7-7, Article 7

2020

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Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem

The AAPS journal, 2015-05, Vol.17 (3), p.631-642

2015

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Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products

The AAPS journal, 2020-07, Vol.22 (5), p.97-97, Article 97

2020

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Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm

Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

Crystalline Nanosuspensions as Potential Toxicology and Clinical Oral Formulations for BCS II/IV Compounds

Use of Preclinical Dog Studies and Absorption Modeling to Facilitate Late Stage Formulation Bridging for a BCS II Drug Candidate

Characteristics of the Human Upper Gastrointestinal Contents in the Fasted State Under Hypo- and A-chlorhydric Gastric Conditions Under Conditions of Typical Drug – Drug Interaction Studies

Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

Physiologically Based Absorption Modeling of Salts of Weak Bases Based on Data in Hypochlorhydric and Achlorhydric Biorelevant Media

Application of Absorption Modeling to Predict Bioequivalence Outcome of Two Batches of Etoricoxib Tablets

Physiologically based Pharmacokinetic Models under the Prism of the Finite Absorption Time Concept

PBPK Absorption Modeling: Establishing the In Vitro–In Vivo Link—Industry Perspective

Applications of Clinically Relevant Dissolution Testing: Workshop Summary Report

Physiologically Based Biopharmaceutics Modeling for Gefapixant IR Formulation Development and Defining the Bioequivalence Dissolution Safe Space

Dissolution and Translational Modeling Strategies Enabling Patient-Centric Drug Product Development: the M-CERSI Workshop Summary Report

Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug–Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect Models

Using Mechanistic Modeling Approaches to Support Bioequivalence Assessments for Oral Products

Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System

Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate

Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report

An IQ Consortium Perspective on Connecting Dissolution Methods to In Vivo Performance: Analysis of an Industrial Database and Case Studies to Propose a Workflow

Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis

A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development

Approaches for Establishing Clinically Relevant Dissolution Specifications for Immediate Release Solid Oral Dosage Forms

Correction to: Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products

Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem

Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products

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