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A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs

Osteoarthritis and cartilage, 2010-09, Vol.18 (9), p.1159-1166

2010

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(S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) and Related Analogues: Isozyme Selective Inhibitors of Protein Kinase Cβ

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2664-2671

1996

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Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2061-2064

2001

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Variations in the turn-forming characteristics of N-Acyl proline units

Biopolymers, 1992-03, Vol.32 (3), p.293-301

1992

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Identification of Potent and Selective Hydantoin Inhibitors of Aggrecanase‑1 and Aggrecanase‑2 That Are Efficacious in Both Chemical and Surgical Models of Osteoarthritis

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10476-10485

2014

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Thermodynamic analysis of .beta.-turn formation in Pro-Ala, Pro-Gly, and Pro-Val model peptides in methylene chloride

Journal of the American Chemical Society, 1992-05, Vol.114 (11), p.4440-4442

1992

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Effects of covalent modifications on the solid-state folding and packing of N-malonylglycine derivatives

Journal of the American Chemical Society, 1992-06, Vol.114 (12), p.4834-4843

1992

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The use of high-throughput synthesis and purification in the preparation of a directed library of adrenergic agents

Molecular diversity, 1997, Vol.3 (2), p.113-116

1997

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Design and Synthesis of α-Aryloxy-α-methylhydrocinnamic Acids: A Novel Class of Dual Peroxisome Proliferator-Activated Receptor α/γ Agonists

Journal of medicinal chemistry, 2004-05, Vol.47 (10), p.2422-2425

2004

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Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis

Bioorganic & medicinal chemistry letters, 2004-12, Vol.14 (24), p.6113-6116

2004

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Macrocyclic Bisindolylmaleimides: Synthesis by Inter- and Intramolecular Alkylation

Journal of organic chemistry, 1998-03, Vol.63 (6), p.1961-1973

1998

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Design and synthesis of 2-methyl-2-[4-(2-[5-methyl-2-aryloxazol-4-yl]ethoxy)phenoxy]propionic acids: a new class of dual PPARalpha/gamma agonists

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2061-2064

2001

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(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

Journal of medicinal chemistry, 1996-07, Vol.39 (14), p.2664-2671

1996

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Synthesis of bisindolylmaleimide macrocycles

Bioorganic & medicinal chemistry letters, 1995-09, Vol.5 (18), p.2093-2096

1995

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ChemInform Abstract: Macrocyclic Bisindolylmaleimides: Synthesis by Inter- and Intramolecular Alkylation

ChemInform, 1998-08, Vol.29 (31), p.no-no

1998

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WHO European Childhood Obesity Surveillance Initiative: associations between sleep duration, screen time and food consumption frequencies

BMC public health, 2015-04, Vol.15 (1), p.442-442, Article 442

2015

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Novel site-specific PEGylated L-asparaginase

PloS one, 2019-02, Vol.14 (2), p.e0211951-e0211951

2019

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ChemInform Abstract: Synthesis of Bisindolylmaleimide Macrocycles

ChemInform, 1996-01, Vol.27 (2), p.no-no

1996

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Differences in biopsychosocial profiles of diabetes patients by level of glycaemic control and health-related quality of life: The Maastricht Study

PloS one, 2017-07, Vol.12 (7), p.e0182053-e0182053

2017

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Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

Molecular systems biology, 2015-12, Vol.11 (12), p.852-n/a

2015

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Physical Activity, Screen Time, and Sleep Duration of Children Aged 6–9 Years in 25 Countries: An Analysis within the WHO European Childhood Obesity Surveillance Initiative (COSI) 2015–2017

Obesity facts, 2021-03, Vol.14 (1), p.32-44

2021

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Projected impact of the Portuguese sugar-sweetened beverage tax on obesity incidence across different age groups: A modelling study

PLoS medicine, 2020-03, Vol.17 (3), p.e1003036

2020

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Evaluating extinction debt in fragmented forests: the rapid recovery of a critically endangered primate

Animal conservation, 2021-06, Vol.24 (3), p.432-444

2021

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Perceived discrimination in patients with multiple sclerosis and depressive symptomatology

Multiple sclerosis and related disorders, 2021-02, Vol.48, p.102705-102705, Article 102705

2021

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A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs

(S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) and Related Analogues: Isozyme Selective Inhibitors of Protein Kinase Cβ

Design and Synthesis of 2-Methyl-2-{4-[2-(5-methyl-2-aryloxazol- 4-yl)ethoxy]phenoxy}propionic Acids: A New Class of Dual PPARα/γ Agonists

Variations in the turn-forming characteristics of N-Acyl proline units

Identification of Potent and Selective Hydantoin Inhibitors of Aggrecanase‑1 and Aggrecanase‑2 That Are Efficacious in Both Chemical and Surgical Models of Osteoarthritis

Thermodynamic analysis of .beta.-turn formation in Pro-Ala, Pro-Gly, and Pro-Val model peptides in methylene chloride

A tailored therapy for the metabolic syndrome: The dual peroxisome proliferator-activated receptor-α/γ agonist LY465608 ameliorates insulin resistance and diabetic hyperglycemia while improving cardiovascular risk factors in preclinical models

Effects of covalent modifications on the solid-state folding and packing of N-malonylglycine derivatives

The use of high-throughput synthesis and purification in the preparation of a directed library of adrenergic agents

Design and Synthesis of α-Aryloxy-α-methylhydrocinnamic Acids: A Novel Class of Dual Peroxisome Proliferator-Activated Receptor α/γ Agonists

Conversion of human-selective PPARα agonists to human/mouse dual agonists: a molecular modeling analysis

Macrocyclic Bisindolylmaleimides: Synthesis by Inter- and Intramolecular Alkylation

Design and synthesis of 2-methyl-2-[4-(2-[5-methyl-2-aryloxazol-4-yl]ethoxy)phenoxy]propionic acids: a new class of dual PPARalpha/gamma agonists

(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

Synthesis of bisindolylmaleimide macrocycles

ChemInform Abstract: Macrocyclic Bisindolylmaleimides: Synthesis by Inter- and Intramolecular Alkylation

WHO European Childhood Obesity Surveillance Initiative: associations between sleep duration, screen time and food consumption frequencies

Novel site-specific PEGylated L-asparaginase

ChemInform Abstract: Synthesis of Bisindolylmaleimide Macrocycles

Differences in biopsychosocial profiles of diabetes patients by level of glycaemic control and health-related quality of life: The Maastricht Study

Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

Physical Activity, Screen Time, and Sleep Duration of Children Aged 6–9 Years in 25 Countries: An Analysis within the WHO European Childhood Obesity Surveillance Initiative (COSI) 2015–2017

Projected impact of the Portuguese sugar-sweetened beverage tax on obesity incidence across different age groups: A modelling study

Evaluating extinction debt in fragmented forests: the rapid recovery of a critically endangered primate

Perceived discrimination in patients with multiple sclerosis and depressive symptomatology

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