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Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections

American journal of human genetics, 2013-08, Vol.93 (2), p.398-404

2013

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Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor

Science signaling, 2014-05, Vol.7 (326), p.ra48

2014

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Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate

Biochemical journal, 2013-08, Vol.454 (1), p.91-99

2013

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Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog

Nature communications, 2019-08, Vol.10 (1), p.1-13, Article 3533

2019

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Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I

Structure (London), 2014-01, Vol.22 (1), p.116-124

2014

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Correction to: Crystal structure of PKG Iβ holoenzyme reveals a trans‑inhibiting dimer assembly

Journal of translational medicine, 2020-01, Vol.18 (1), p.27-27, Article 27

2020

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Regulation of Gene Expression by Cyclic GMP

Circulation research, 2003-11, Vol.93 (11), p.1034-1046

2003

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Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation

Structure (London), 2016-05, Vol.24 (5), p.710-720

2016

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cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss

Journal of endocrinology, 2018-09, Vol.238 (3), p.203-219

2018

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Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

Structure (London), 2011-09, Vol.19 (9), p.1317-1327

2011

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An auto-inhibited state of protein kinase G and implications for selective activation

eLife, 2022-08, Vol.11

2022

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Letter by Casteel Regarding Article, “Blood Pressure-Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of the cGMP-Dependent Protein Kinase”

Circulation (New York, N.Y.), 2019-11, Vol.140 (22), p.e808-e809

Casteel, Darren E

2019

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Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts

Science signaling, 2010-12, Vol.3 (153), p.ra91

2010

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Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding

PloS one, 2011-04, Vol.6 (4), p.e18413-e18413

2011

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Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions

The Journal of biological chemistry, 2014-09, Vol.289 (37), p.25393-25403

2014

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Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3

The Journal of biological chemistry, 2023-04, Vol.299 (4), p.104584-104584, Article 104584

2023

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PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells

The Journal of biological chemistry, 2022-08, Vol.298 (8), p.102175-102175, Article 102175

2022

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The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43

The Journal of biological chemistry, 2017-05, Vol.292 (20), p.8262-8268

2017

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A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells

Science signaling, 2024-01, Vol.17 (821), p.eadi7861

2024

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Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes

Diabetes (New York, N.Y.), 2018-04, Vol.67 (4), p.607-623

2018

Volltextzugriff (PDF)

A Novel, Direct NO Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice

Journal of bone and mineral research, 2017-01, Vol.32 (1), p.46-59

2017

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Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46

The Journal of biological chemistry, 2018-07, Vol.293 (28), p.10985-10992

2018

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A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP

The Journal of biological chemistry, 2020-07, Vol.295 (30), p.10394-10405

2020

Volltextzugriff (PDF)

Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2–Driven Regulation of Nitric Oxide and Invadopodia Formation

The American journal of pathology, 2021-12, Vol.191 (12), p.2203-2218

2021

Volltextzugriff (PDF)

O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts

The Journal of biological chemistry, 2016-12, Vol.291 (51), p.26515-26528

2016

Volltextzugriff (PDF)

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Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections

Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor

Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog

Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I

Correction to: Crystal structure of PKG Iβ holoenzyme reveals a trans‑inhibiting dimer assembly

Regulation of Gene Expression by Cyclic GMP

Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation

cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss

Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

An auto-inhibited state of protein kinase G and implications for selective activation

Letter by Casteel Regarding Article, “Blood Pressure-Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of the cGMP-Dependent Protein Kinase”

Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts

Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding

Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions

Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3

PKGIα is activated by metal-dependent oxidation in vitro but not in intact cells

The activity of cGMP-dependent protein kinase Iα is not directly regulated by oxidation-induced disulfide formation at cysteine 43

A plasma membrane-associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells

Protein Kinase G Activation Reverses Oxidative Stress and Restores Osteoblast Function and Bone Formation in Male Mice With Type 1 Diabetes

A Novel, Direct NO Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice

Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46

A substitution in cGMP-dependent protein kinase 1 associated with aortic disease induces an active conformation in the absence of cGMP

Bladder Cancer Invasion Is Mediated by Mammalian Target of Rapamycin Complex 2–Driven Regulation of Nitric Oxide and Invadopodia Formation

O-GlcNAcylation of 8-Oxoguanine DNA Glycosylase (Ogg1) Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts

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