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CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

1, 2022

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FecBB mutation enhances follicle stimulating hormone sensitivity of granulosa cells by up-regulating the SMAD1/5–USF1–FSHR signaling pathway

International journal of biological macromolecules, 2024-11, Vol.280 (Pt 1), p.135697, Article 135697

2024

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DISSECTING THE PD-1/PD-L1 AXIS IN MELANOMA USING A MICRORNA-BASED FINE-TUNING APPROACH

Cytotherapy (Oxford, England), 2024-06, Vol.26 (6), p.S213-S213

2024

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A snapshot of Lithuania's life-sciences landscape

Nature (London), 2024-05

Thornton, Jacqui

2024

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Abstract 1372 The generation of an engineered HEK293T cell line bearing mutant NEMO incapable of binding to secondary binding site

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106884, Article 106884

2024

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Multigene Knockout Utilizing Off-Target Mutations of the CRISPR/Cas9 System in Rice

Plant and cell physiology, 2015-01, Vol.56 (1), p.41-47

2015

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Comprehensive UHPLC- and CE-based methods for engineered Cas9 characterization

Talanta (Oxford), 2023-01, Vol.252, p.123780-123780, Article 123780

2023

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CRISPR/Cas9

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2637, p.41

2023

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Hybrid Rubisco with Complete Replacement of Rice Rubisco Small Subunits by Sorghum Counterparts Confers C4 Plant-like High Catalytic Activity

Molecular plant, 2020-11, Vol.13 (11), p.1570-1581

2020

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ADVANCING CARDIAC GENE THERAPY THROUGH EXOSOME-ENCAPSULATED CRISPR-CAS9 RIBONUCLEOPROTEINS

Cytotherapy (Oxford, England), 2024-06, Vol.26 (6), p.S83-S83

2024

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CAS9-MEDIATED PRECISE AND TEMPLATE-FREE GENE EDITING OF A MUSCULAR DYSTROPHY FOUNDER MUTATION: FROM SINGLE EDITING AND OFF-TARGET ANALYSIS TO DOUBLE EDITING AND CLINICAL TRANSLATION

Cytotherapy (Oxford, England), 2024-06, Vol.26 (6), p.S29-S29

2024

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Melanotransferrin (MELTF, MFI2, CD228) Expression Attenuates Malignant Melanoma Progression in the A375-Luc2 Murine Metastasis Model and Human Patients

Journal of investigative dermatology, 2024-06

2024

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Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4Hpa

Journal of molecular biology, 2022-03, Vol.434 (5), p.167420-167420, Article 167420

2022

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A CRISPR first produces squid as clear as glass

Nature (London), 2020-08, Vol.584 (7819), p.11-11

2020

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Epigenome profiling and editing of neocortical progenitor cells during development

The EMBO journal, 2017-09, Vol.36 (17), p.2642-2658

2017

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sgRNA structure optimization and PTG/Cas9 system synergistically boost gene knockout efficiency in an insect

International journal of biological macromolecules, 2024-11, Vol.280 (Pt 1), p.135413, Article 135413

2024

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Disruption of G0/G1 switch gene 2 (G0S2) reduced abdominal fat deposition and altered fatty acid composition in chicken

The FASEB journal, 2019-01, Vol.33 (1), p.1188-1198

2019

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TRANSLATION OF TACROLIMUS RESISTANT ANTIVIRAL T CELL PRODUCTS: IN DEPTH-EFFICACY EVALUATION AND HUMAN BASED SAFETY ASSESSMENT

Cytotherapy (Oxford, England), 2024-06, Vol.26 (6), p.e23-e24

2024

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Single step production of Cas9 mRNA for zygote injection

BioTechniques, 2018-03, Vol.64 (3), p.118-124

2018

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RNA lipid nanoparticles as efficient in vivo CRISPR-Cas9 gene editing tool for therapeutic target validation in glioblastoma cancer stem cells

Journal of controlled release, 2024-09, Vol.375, p.776-787

2024

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Targeted manipulation of m6A RNA modification through CRISPR-Cas-based strategies

Methods (San Diego, Calif.), 2022-07, Vol.203, p.56-61

2022

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I fell out of love with the lab, and in love with business

Nature (London), 2024-05

Thornton, Jacqui

2024

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How I'm supporting other researchers who have moved to Lithuania

Nature (London), 2024-05

Thornton, Jacqui

2024

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How bioinformatics led one scientist home to Lithuania

Nature (London), 2024-05

Thornton, Jacqui

2024

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Biomimetic Fe3+ metal-phenolic networks enable DNAzyme and Cas9 RNP delivery for synergistic tumor ferroptosis-immunotherapy

Chemical engineering journal (Lausanne, Switzerland : 1996), 2024-11, Vol.499, p.156050, Article 156050

2024

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CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

FecBB mutation enhances follicle stimulating hormone sensitivity of granulosa cells by up-regulating the SMAD1/5–USF1–FSHR signaling pathway

DISSECTING THE PD-1/PD-L1 AXIS IN MELANOMA USING A MICRORNA-BASED FINE-TUNING APPROACH

A snapshot of Lithuania's life-sciences landscape

Abstract 1372 The generation of an engineered HEK293T cell line bearing mutant NEMO incapable of binding to secondary binding site

Multigene Knockout Utilizing Off-Target Mutations of the CRISPR/Cas9 System in Rice

Comprehensive UHPLC- and CE-based methods for engineered Cas9 characterization

CRISPR/Cas9

Hybrid Rubisco with Complete Replacement of Rice Rubisco Small Subunits by Sorghum Counterparts Confers C4 Plant-like High Catalytic Activity

ADVANCING CARDIAC GENE THERAPY THROUGH EXOSOME-ENCAPSULATED CRISPR-CAS9 RIBONUCLEOPROTEINS

CAS9-MEDIATED PRECISE AND TEMPLATE-FREE GENE EDITING OF A MUSCULAR DYSTROPHY FOUNDER MUTATION: FROM SINGLE EDITING AND OFF-TARGET ANALYSIS TO DOUBLE EDITING AND CLINICAL TRANSLATION

Melanotransferrin (MELTF, MFI2, CD228) Expression Attenuates Malignant Melanoma Progression in the A375-Luc2 Murine Metastasis Model and Human Patients

Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4Hpa

A CRISPR first produces squid as clear as glass

Epigenome profiling and editing of neocortical progenitor cells during development

sgRNA structure optimization and PTG/Cas9 system synergistically boost gene knockout efficiency in an insect

Disruption of G0/G1 switch gene 2 (G0S2) reduced abdominal fat deposition and altered fatty acid composition in chicken

TRANSLATION OF TACROLIMUS RESISTANT ANTIVIRAL T CELL PRODUCTS: IN DEPTH-EFFICACY EVALUATION AND HUMAN BASED SAFETY ASSESSMENT

Single step production of Cas9 mRNA for zygote injection

RNA lipid nanoparticles as efficient in vivo CRISPR-Cas9 gene editing tool for therapeutic target validation in glioblastoma cancer stem cells

Targeted manipulation of m6A RNA modification through CRISPR-Cas-based strategies

I fell out of love with the lab, and in love with business

How I'm supporting other researchers who have moved to Lithuania

How bioinformatics led one scientist home to Lithuania

Biomimetic Fe3+ metal-phenolic networks enable DNAzyme and Cas9 RNP delivery for synergistic tumor ferroptosis-immunotherapy

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