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Azole-resistant Aspergillus fumigatus harboring TR 34 /L98H, TR 46 /Y121F/T289A and TR 53 mutations related to flower fields in Colombia

Scientific reports, 2017-03, Vol.7, p.45631

2017

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An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

Nature communications, 2020-12, Vol.11 (1), p.6429-17, Article 6429

2020

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A safe lithium mimetic for bipolar disorder

Nature communications, 2013-01, Vol.4 (1), p.1332-1332, Article 1332

2013

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Posttranslational chemical installation of azoles into translated peptides

Nature communications, 2021-01, Vol.12 (1), p.696-696, Article 696

2021

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Can you teach old drugs new tricks?

Nature (London), 2016-06, Vol.534 (7607), p.314-316

Nosengo, Nicola

2016

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Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition

Nature communications, 2019-10, Vol.10 (1), p.4563-11, Article 4563

2019

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Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2

Scientific reports, 2021-02, Vol.11 (1), p.3640-3640, Article 3640

2021

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The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

Nature communications, 2020-01, Vol.11 (1), p.427-427, Article 427

2020

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The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation

Nature communications, 2018-04, Vol.9 (1), p.1693-9, Article 1693

2018

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Structural design of microbicidal cationic oligomers and their synergistic interaction with azoles against Candida albicans

Scientific reports, 2019-08, Vol.9 (1), p.11885-11, Article 11885

2019

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Azole-induced cell wall carbohydrate patches kill Aspergillus fumigatus

Nature communications, 2018-08, Vol.9 (1), p.3098-13, Article 3098

2018

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Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase

Scientific reports, 2017-11, Vol.7 (1), p.15898-10, Article 15898

2017

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Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy

Communications biology, 2020-03, Vol.3 (1), p.97-97, Article 97

2020

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Cryo-EM structures of Candida albicans Cdr1 reveal azole-substrate recognition and inhibitor blocking mechanisms

Nature communications, 2024-09, Vol.15 (1), p.7722-11, Article 7722

2024

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cyp51A mutations, protein modeling, and efflux pump gene expression reveals multifactorial complexity towards understanding Aspergillus section Nigri azole resistance mechanism

Scientific reports, 2024-03, Vol.14 (1), p.6156-6156, Article 6156

2024

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Ultra-fast proteomics with Scanning SWATH

Nature biotechnology, 2021-07, Vol.39 (7), p.846-854

2021

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The rapid emergence of antifungal-resistant human-pathogenic fungi

Nature reviews. Microbiology, 2023-12, Vol.21 (12), p.818-832

2023

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Catechol thwarts virulent dimorphism in Candida albicans and potentiates the antifungal efficacy of azoles and polyenes

Scientific reports, 2021-10, Vol.11 (1), p.21049-21049, Article 21049

2021

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Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

Nature communications, 2024-06, Vol.15 (1), p.4984-16, Article 4984

2024

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Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen

Nature communications, 2013-11, Vol.4 (1), p.2748-2748, Article 2748

2013

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Azole sensitivity in Leptosphaeria pathogens of oilseed rape: the role of lanosterol 14α-demethylase

Scientific reports, 2017-11, Vol.7 (1), p.15849-12, Article 15849

2017

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Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus

Nature communications, 2024-07, Vol.15 (1), p.6312-14, Article 6312

2024

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Azoles activate type I and type II programmed cell death pathways in crop pathogenic fungi

Nature communications, 2024-05, Vol.15 (1), p.4357-21, Article 4357

2024

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Address the growing urgency of fungal disease in crops

Nature (London), 2023-05, Vol.617 (7959), p.31-34

2023

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Organocatalytic atroposelective construction of axially chiral N, N- and N, S-1,2-azoles through novel ring formation approach

Nature communications, 2022-04, Vol.13 (1), p.1933-1933, Article 1933

2022

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Azole-resistant Aspergillus fumigatus harboring TR 34 /L98H, TR 46 /Y121F/T289A and TR 53 mutations related to flower fields in Colombia

An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

A safe lithium mimetic for bipolar disorder

Posttranslational chemical installation of azoles into translated peptides

Can you teach old drugs new tricks?

Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition

Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation

Structural design of microbicidal cationic oligomers and their synergistic interaction with azoles against Candida albicans

Azole-induced cell wall carbohydrate patches kill Aspergillus fumigatus

Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase

Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy

Cryo-EM structures of Candida albicans Cdr1 reveal azole-substrate recognition and inhibitor blocking mechanisms

cyp51A mutations, protein modeling, and efflux pump gene expression reveals multifactorial complexity towards understanding Aspergillus section Nigri azole resistance mechanism

Ultra-fast proteomics with Scanning SWATH

The rapid emergence of antifungal-resistant human-pathogenic fungi

Catechol thwarts virulent dimorphism in Candida albicans and potentiates the antifungal efficacy of azoles and polyenes

Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen

Azole sensitivity in Leptosphaeria pathogens of oilseed rape: the role of lanosterol 14α-demethylase

Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus

Azoles activate type I and type II programmed cell death pathways in crop pathogenic fungi

Address the growing urgency of fungal disease in crops

Organocatalytic atroposelective construction of axially chiral N, N- and N, S-1,2-azoles through novel ring formation approach

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