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The story of PKC: A discovery marked by unexpected twists and turns

IUBMB life, 2019-06, Vol.71 (6), p.697-705

Kikkawa, Ushio

2019

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Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

The Journal of biological chemistry, 2010-06, Vol.285 (26), p.20109-20116

2010

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Proline dehydrogenase promotes senescence through the generation of reactive oxygen species

Journal of cell science, 2017-04, Vol.130 (8), p.1413-1420

2017

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Identification of cellular senescence-specific genes by comparative transcriptomics

Scientific reports, 2016-08, Vol.6 (1), p.31758-31758, Article 31758

2016

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Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells

Cell death & disease, 2021-09, Vol.12 (10), p.884-13, Article 884

2021

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Nuclear Translocation of Caspase-3 Is Dependent on Its Proteolytic Activation and Recognition of a Substrate-like Protein(s)

The Journal of biological chemistry, 2005-01, Vol.280 (2), p.857-860

2005

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The Proline-rich Akt Substrate of 40 kDa (PRAS40) Is a Physiological Substrate of Mammalian Target of Rapamycin Complex 1

The Journal of biological chemistry, 2007-07, Vol.282 (28), p.20329-20339

2007

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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation

Journal of biomedical science, 2022-03, Vol.29 (1), p.21-21, Article 21

2022

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Protein Kinase Cδ (PKCδ): Activation Mechanisms and Functions

Journal of biochemistry (Tokyo), 2002-12, Vol.132 (6), p.831-839

2002

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Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family

Journal of biomedical science, 2015-07, Vol.22 (1), p.48, Article 48

2015

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Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein

PloS one, 2013-11, Vol.8 (11), p.e80411-e80411

2013

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The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast

PloS one, 2016-05, Vol.11 (5), p.e0156239-e0156239

2016

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Growth hormone and Insulin-like growth factor-I (IGF-I) modulate the expression of L-type amino acid transporters in the muscles of spontaneous dwarf rats and L6 and C2C12 myocytes

Growth hormone & IGF research, 2018-10, Vol.42-43, p.66-73

2018

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HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells

Journal of experimental & clinical cancer research, 2022-02, Vol.41 (1), p.47-47, Article 47

2022

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The S. pombe CDK5 Orthologue Pef1 Cooperates with Three Cyclins, Clg1, Pas1 and Psl1, to Promote Pre-Meiotic DNA Replication

Biomolecules (Basel, Switzerland), 2021-01, Vol.11 (1), p.89

2021

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Versatile function of the circadian protein CIPC as a regulator of Erk activation

Biochemical and biophysical research communications, 2016-01, Vol.469 (3), p.377-383

2016

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Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (5), p.1909-1914

2014

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Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 complex

PloS one, 2014-04, Vol.9 (4), p.e93940-e93940

2014

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Proline dehydrogenase promotes senescence through the generation of reactive oxygen species

Development (Cambridge), 2017-05, Vol.144 (9), p.e1.1-e1.1

2017

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Contribution of caspase(s) to the cell cycle regulation at mitotic phase

PloS one, 2011-03, Vol.6 (3), p.e18449

2011

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AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity

Genes to cells : devoted to molecular & cellular mechanisms, 2009-02, Vol.14 (2), p.179-189

2009

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Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells

Journal of biomedical science, 2012-07, Vol.19 (1), p.64-64, Article 64

2012

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RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth

Biomolecules (Basel, Switzerland), 2021-12, Vol.11 (12), p.1814

2021

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d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species

Life science alliance, 2019-02, Vol.2 (1), p.e201800045

2019

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Activation of Protein Kinase C by Tyrosine Phosphorylation in Response to H2O2

Proceedings of the National Academy of Sciences - PNAS, 1997-10, Vol.94 (21), p.11233-11237

1997

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The story of PKC: A discovery marked by unexpected twists and turns

Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

Proline dehydrogenase promotes senescence through the generation of reactive oxygen species

Identification of cellular senescence-specific genes by comparative transcriptomics

Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells

Nuclear Translocation of Caspase-3 Is Dependent on Its Proteolytic Activation and Recognition of a Substrate-like Protein(s)

The Proline-rich Akt Substrate of 40 kDa (PRAS40) Is a Physiological Substrate of Mammalian Target of Rapamycin Complex 1

Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation

Protein Kinase Cδ (PKCδ): Activation Mechanisms and Functions

Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family

Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein

The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast

Growth hormone and Insulin-like growth factor-I (IGF-I) modulate the expression of L-type amino acid transporters in the muscles of spontaneous dwarf rats and L6 and C2C12 myocytes

HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells

The S. pombe CDK5 Orthologue Pef1 Cooperates with Three Cyclins, Clg1, Pas1 and Psl1, to Promote Pre-Meiotic DNA Replication

Versatile function of the circadian protein CIPC as a regulator of Erk activation

Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1

Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 complex

Proline dehydrogenase promotes senescence through the generation of reactive oxygen species

Contribution of caspase(s) to the cell cycle regulation at mitotic phase

AMP-activated protein kinase phosphorylates glutamine : fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity

Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells

RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth

d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species

Activation of Protein Kinase C by Tyrosine Phosphorylation in Response to H2O2

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