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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

Cell reports (Cambridge), 2019-12, Vol.29 (10), p.3073-3086.e5

2019

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Probiotic normalization of systemic inflammation in siblings of type 1 diabetes patients: an open-label pilot study

Scientific reports, 2022-02, Vol.12 (1), p.3306-3306, Article 3306

2022

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Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice

International journal of molecular sciences, 2021-04, Vol.22 (7), p.3767

2021

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Gene targeting in NOD mouse embryos using zinc-finger nucleases

Diabetes (New York, N.Y.), 2014-01, Vol.63 (1), p.68-74

2014

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Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes

Cell metabolism, 2020-04, Vol.31 (4), p.822-836.e5

2020

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Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes

The Journal of immunology (1950), 2023-04, Vol.210 (7), p.935-946

2023

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Self-Renewing Islet TCF1+ CD8 T Cells Undergo IL-27–Controlled Differentiation to Become TCF1− Terminal Effectors during the Progression of Type 1 Diabetes

The Journal of immunology (1950), 2021-10, Vol.207 (8), p.1990-2004

2021

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The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137 + FOXP3 + Regulatory CD4 T Cells

The Journal of immunology (1950), 2020-06, Vol.204 (11), p.2887-2899

2020

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UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice

Scientific reports, 2020-07, Vol.10 (1), p.12019, Article 12019

2020

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CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice

The Journal of immunology (1950), 2017-05, Vol.198 (10), p.3857-3868

2017

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Interleukin-27 is essential for type 1 diabetes development and Sjögren syndrome-like inflammation

Cell reports (Cambridge), 2021-02, Vol.34 (5), p.108725-108725, Article 108725

2021

Volltextzugriff (PDF)

Autoreactive CD8 T cells in NOD mice exhibit phenotypic heterogeneity but restricted TCR gene usage

Life science alliance, 2022-10, Vol.5 (10), p.e202201503

2022

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Monocytes in type 1 diabetes families exhibit high cytolytic activity and subset abundances that correlate with clinical progression

Science advances, 2024-05, Vol.10 (20), p.eadn2136-eadn2136

2024

Volltextzugriff (PDF)

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice

Immunogenetics (New York), 2017-03, Vol.69 (3), p.193-198

2017

Volltextzugriff (PDF)

Heterogeneity of islet-infiltrating interleukin-21+ CD4 T cells in a mouse model of type 1 diabetes

The Journal of immunology (1950), 2023-04, Vol.210 (7), p.935-946

2023

Volltextzugriff (PDF)

Self-renewing islet TCF1+ CD8 T cells undergo interleukin-27 controlled differentiation to become TCF1− terminal effectors during the progression of type 1 diabetes

The Journal of immunology (1950), 2021-09, Vol.207 (8), p.1990-2004

2021

Volltextzugriff (PDF)

Interleukin 27 signaling in T cells is essential for the development of type 1 diabetes

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.163-163.4

2018

Volltextzugriff (PDF)

The absence of CD137 ligand upregulates the expression of the immunosuppressive molecule soluble CD137

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.116-116.9

2019

Volltextzugriff (PDF)

Single-cell transcriptome analysis reveals diverse islet-infiltrating T cell subsets and a role for BATF in promoting the diabetogenic activity of CD8 T cells

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.115-115.20

2019

Volltextzugriff (PDF)

Investigating the Role of CD137 Ligand in the Pathogenesis of Type 1 Diabetes

Diabetes (New York, N.Y.), 2018-07, Vol.67 (Supplement_1)

2018

Volltextzugriff (PDF)

Probiotic Supplementation with Lactobacillus plantarum 299v Lowers Systemic Inflammation, Reduces Islet ER Stress and Prevents Type 1 Diabetes in BioBreeding Rats

Journal of the Endocrine Society, 2021-05, Vol.5 (Supplement_1), p.A661-A662

2021

Volltextzugriff (PDF)

A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells

Genes and immunity, 2015-04, Vol.16 (3), p.221-230

2015

Volltextzugriff (PDF)

Genetic control of murine invariant natural killer T cells maps to multiple type 1 diabetes regions

Genes and immunity, 2013-09, Vol.14 (6), p.380-386

2013

Volltextzugriff (PDF)

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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

Probiotic normalization of systemic inflammation in siblings of type 1 diabetes patients: an open-label pilot study

Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice

Gene targeting in NOD mouse embryos using zinc-finger nucleases

Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes

Heterogeneity of Islet-Infiltrating IL-21+ CD4 T Cells in a Mouse Model of Type 1 Diabetes

Self-Renewing Islet TCF1+ CD8 T Cells Undergo IL-27–Controlled Differentiation to Become TCF1− Terminal Effectors during the Progression of Type 1 Diabetes

The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137 + FOXP3 + Regulatory CD4 T Cells

UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice

CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice

Interleukin-27 is essential for type 1 diabetes development and Sjögren syndrome-like inflammation

Autoreactive CD8 T cells in NOD mice exhibit phenotypic heterogeneity but restricted TCR gene usage

Monocytes in type 1 diabetes families exhibit high cytolytic activity and subset abundances that correlate with clinical progression

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice

Heterogeneity of islet-infiltrating interleukin-21+ CD4 T cells in a mouse model of type 1 diabetes

Self-renewing islet TCF1+ CD8 T cells undergo interleukin-27 controlled differentiation to become TCF1− terminal effectors during the progression of type 1 diabetes

Interleukin 27 signaling in T cells is essential for the development of type 1 diabetes

The absence of CD137 ligand upregulates the expression of the immunosuppressive molecule soluble CD137

Single-cell transcriptome analysis reveals diverse islet-infiltrating T cell subsets and a role for BATF in promoting the diabetogenic activity of CD8 T cells

Investigating the Role of CD137 Ligand in the Pathogenesis of Type 1 Diabetes

Probiotic Supplementation with Lactobacillus plantarum 299v Lowers Systemic Inflammation, Reduces Islet ER Stress and Prevents Type 1 Diabetes in BioBreeding Rats

A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells

Genetic control of murine invariant natural killer T cells maps to multiple type 1 diabetes regions

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