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Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?

Life sciences (1973), 2010-04, Vol.86 (15), p.590-597

Filizola, Marta

2010

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Identification of a serotonin/glutamate receptor complex implicated in psychosis

Nature, 2008-03, Vol.452 (7183), p.93-97

2008

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Opioid receptors: Structural and mechanistic insights into pharmacology and signaling

European journal of pharmacology, 2015-09, Vol.763 (Pt B), p.206-213

2015

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GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

Bioinformatics, 2010-07, Vol.26 (14), p.1804-1805

2010

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Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer

Journal of computer-aided molecular design, 2006-08, Vol.20 (7-8), p.405-416

2006

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Deciphering downstream receptor signaling

Science (American Association for the Advancement of Science), 2023-12, Vol.382 (6677), p.1357-1358

2023

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Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures

British journal of pharmacology, 2018-07, Vol.175 (14), p.2834-2845

2018

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Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora' s box for novel drug discovery?

Life sciences (1973), 2010-04, Vol.86 (15-16), p.590-597

Filizola, Marta

2010

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Cryo-Electron Microscopy Structure of the αIIbβ3-Abciximab Complex

Arteriosclerosis, thrombosis, and vascular biology, 2020-03, Vol.40 (3), p.624

2020

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Structural biology: How opioid drugs bind to receptors

Nature (London), 2012-05, Vol.485 (7398), p.314

2012

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The study of G‐protein coupled receptor oligomerization with computational modeling and bioinformatics

The FEBS journal, 2005-06, Vol.272 (12), p.2926-2938

2005

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How opioid drugs bind to receptors: the search for safe, non-addictive versions of morphine and other opioid drugs has just received a boost with the solving of the crystal structures of the receptors to which the drugs bind

Nature (London), 2012-05, Vol.485 (7398), p.314

2012

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Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R

Science advances, 2024-04, Vol.10 (16), p.eadk4855

2024

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Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT1eR and 5-HT1FR

Science advances, 2024-04, Vol.10 (16), p.eadk4855-eadk4855

2024

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Implementation of an Online Reporting System to Identify Unprofessional Behaviors and Mistreatment Directed at Trainees at an Academic Medical Center

JAMA network open, 2022-12, Vol.5 (12), p.e2244661-e2244661

2022

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How opioid drugs bind to receptors

Nature (London), 2012-05, Vol.485 (7398), p.314-317

2012

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Activation of the G(s) heterotrimer monitored in living cells with novel G(s) biosensors

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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TRAJELIX: a computational tool for the geometric characterization of protein helices during molecular dynamics simulations

Journal of computer-aided molecular design, 2006-02, Vol.20 (2), p.97-107

2006

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RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction

Arteriosclerosis, thrombosis, and vascular biology, 2014-10, Vol.34 (10), p.2321

2014

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MINIREVIEW SERIES: The study of G-protein coupled receptor oligomerization with computational modeling and bioinformatics

The FEBS journal, 2005-06, Vol.272 (12), p.2926-2938

2005

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Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method

Protein engineering, 2002-11, Vol.15 (11), p.881-885

2002

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Structure-based virtual screening of small-molecule antagonists of platelet integrin αIIbβ3 that do not prime the receptor to bind ligand

Journal of computer-aided molecular design, 2012-09, Vol.26 (9), p.1005-1015

2012

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Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS

Science translational medicine, 2012-03, Vol.4 (125), p.125ra32

2012

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Transmembrane five effects on functional selectivity at the dopamine D2L receptor

The FASEB journal, 2006-03, Vol.20 (4), p.A246-A246

2006

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Identification of a Novel Serotonin/Glutamate Receptor Complex Implicated in Psychosis

Nature (London), 2008-02, Vol.452 (7183), p.93-97

2008

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Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?

Identification of a serotonin/glutamate receptor complex implicated in psychosis

Opioid receptors: Structural and mechanistic insights into pharmacology and signaling

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base

Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer

Deciphering downstream receptor signaling

Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures

Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora' s box for novel drug discovery?

Cryo-Electron Microscopy Structure of the αIIbβ3-Abciximab Complex

Structural biology: How opioid drugs bind to receptors

The study of G‐protein coupled receptor oligomerization with computational modeling and bioinformatics

How opioid drugs bind to receptors: the search for safe, non-addictive versions of morphine and other opioid drugs has just received a boost with the solving of the crystal structures of the receptors to which the drugs bind

Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R

Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT1eR and 5-HT1FR

Implementation of an Online Reporting System to Identify Unprofessional Behaviors and Mistreatment Directed at Trainees at an Academic Medical Center

How opioid drugs bind to receptors

Activation of the G(s) heterotrimer monitored in living cells with novel G(s) biosensors

TRAJELIX: a computational tool for the geometric characterization of protein helices during molecular dynamics simulations

RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction

MINIREVIEW SERIES: The study of G-protein coupled receptor oligomerization with computational modeling and bioinformatics

Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method

Structure-based virtual screening of small-molecule antagonists of platelet integrin αIIbβ3 that do not prime the receptor to bind ligand

Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS

Transmembrane five effects on functional selectivity at the dopamine D2L receptor

Identification of a Novel Serotonin/Glutamate Receptor Complex Implicated in Psychosis

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