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Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment

Nucleic acid therapeutics, 2019-02, Vol.29 (1), p.1

2019

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Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

Molecular therapy. Nucleic acids, 2012-08, Vol.1 (8), p.e38-e38, Article e38

2012

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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

Organic & biomolecular chemistry, 2013-11, Vol.11 (43), p.7621-7630

2013

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Cell penetrating peptide conjugates of steric block oligonucleotides

Advanced drug delivery reviews, 2008-03, Vol.60 (4), p.517-529

2008

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Targeting the HIV-1 RNA leader sequence with synthetic oligonucleotides and siRNA: Chemistry and cell delivery

Biochimica et biophysica acta, 2006-03, Vol.1758 (3), p.290-300

2006

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Synthesis of Peptide−Oligonucleotide Conjugates with Single and Multiple Peptides Attached to 2‘-Aldehydes through Thiazolidine, Oxime, and Hydrazine Linkages

Bioconjugate chemistry, 2002-07, Vol.13 (4), p.822-830

2002

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Overview of alternative oligonucleotide chemistries for exon skipping

Methods in molecular biology (Clifton, N.J.), 2012, Vol.867, p.365

2012

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Splice redirection as a convenient assay to monitor CPP-ON efficiency and mechanism

Methods in molecular biology (Clifton, N.J.), 2011, Vol.683, p.307

2011

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PNA-peptide conjugates as intracellular gene control agents

Nucleic Acids Symposium Series, 2008, Vol.52 (1), p.31-32

2008

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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargoElectronic supplementary information (ESI) available: MALDI mass-spectroscopy data for peptides and PNA705 conjugates of LB1 and LB2. Amino acid sequences, purity, synthesis and conjugation yields of LB2. Examples of HPLC-graphs and MALDI mass-spectra for peptides and conjugates. Luciferase readout of LB1 crude and purified PNA705 conjugates and single data-point splice correction a

2013-10

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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo† †Electronic supplementary information (ESI) available: MALDI mass-spectroscopy data for peptides and PNA705 conjugates of LB1 and LB2. Amino acid sequences, purity, synthesis and conjugation yields of LB2. Examples of HPLC-graphs and MALDI mass-spectra for peptides and conjugates. Luciferase readout of LB1 crude and purified PNA705 conjugates and single data-point splice correctio

Organic & biomolecular chemistry, 2013-10, Vol.11 (43), p.7621-7630

2013

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Cell penetrating peptide conjugates of steric block oligonucleotides: Membrane Permeable Peptide Vectors: Chemistry and Functional Design for the Therapeutic Applications

Advanced drug delivery reviews, 2008, Vol.60 (4-5), p.517-529

2008

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Terminal deoxynucleotidyl transferasecatalysis of DNA (oligodeoxynucleotide) phosphorylation

Pharmacology & therapeutics (Oxford), 2000-03, Vol.85 (3), p.165-173

2000

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Terminal deoxynucleotidyl transferase: catalysis of DNA (oligodeoxynucleotide) phosphorylation

Pharmacology & therapeutics (Oxford), 2000-03, Vol.85 (3), p.165-173

2000

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Stereoisomers of deoxynucleoside 5'-triphosphates as substrates for template-dependent and -independent DNA polymerases

The Journal of biological chemistry, 1997-04, Vol.272 (14), p.9556-9560

1997

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Î³-Phosphate-substituted 2â²-Deoxynucleoside 5â²-Triphosphates as Substrates for DNA Polymerases

The Journal of biological chemistry, 1996-10, Vol.271 (40), p.24389

1996

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Stereoisomers of Deoxynucleoside 5â²-Triphosphates as Substrates for Template-dependent and -independent DNA Polymerases

The Journal of biological chemistry, 1997-04, Vol.272 (14), p.9556

1997

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Development of technology for the construction of heat-efficient monolithic vaults from basalt fiber concrete

E3S Web of Conferences, 2021, Vol.258, p.9041

2021

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Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression

Molecular therapy. Nucleic acids, 2023-12, Vol.34, p.102024, Article 102024

2023

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2‘-O-Methyl-RNA Hairpins Generate Loop−Loop Complexes and Selectively Inhibit HIV-1 Tat-Mediated Transcription

Biochemistry (Easton), 2002-10, Vol.41 (40), p.12186-12192

2002

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Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (15), p.9709-9714

2002

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Hexitol Nucleic Acid-Containing Aptamers Are Efficient Ligands of HIV-1 TAR RNA

Biochemistry (Easton), 2005-03, Vol.44 (8), p.2926-2933

2005

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Inhibition of HIV-1 Replication by Oligonucleotide Analogues Directed to the Packaging Signal and Trans-Activating Response Region

Antiviral chemistry & chemotherapy, 2006-02, Vol.17 (1), p.1-9

2006

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Loop-Loop Interaction of HIV-1 TAR RNA with N3t' → P5′ Deoxyphosphoramidate Aptamers Inhibits in vitro Tat-Mediated Transcription

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (15), p.9709-9714

2002

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Oligonucleotide inhibition of the interaction of HIV-1 Tat protein with the trans-activation responsive region (TAR) of HIV RNA

Biochimica et biophysica acta, 1999-04, Vol.1445 (1), p.86-98

1999

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Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

Cell penetrating peptide conjugates of steric block oligonucleotides

Targeting the HIV-1 RNA leader sequence with synthetic oligonucleotides and siRNA: Chemistry and cell delivery

Synthesis of Peptide−Oligonucleotide Conjugates with Single and Multiple Peptides Attached to 2‘-Aldehydes through Thiazolidine, Oxime, and Hydrazine Linkages

Overview of alternative oligonucleotide chemistries for exon skipping

Splice redirection as a convenient assay to monitor CPP-ON efficiency and mechanism

PNA-peptide conjugates as intracellular gene control agents

Cell penetrating peptide conjugates of steric block oligonucleotides: Membrane Permeable Peptide Vectors: Chemistry and Functional Design for the Therapeutic Applications

Terminal deoxynucleotidyl transferasecatalysis of DNA (oligodeoxynucleotide) phosphorylation

Terminal deoxynucleotidyl transferase: catalysis of DNA (oligodeoxynucleotide) phosphorylation

Stereoisomers of deoxynucleoside 5'-triphosphates as substrates for template-dependent and -independent DNA polymerases

Î³-Phosphate-substituted 2â²-Deoxynucleoside 5â²-Triphosphates as Substrates for DNA Polymerases

Stereoisomers of Deoxynucleoside 5â²-Triphosphates as Substrates for Template-dependent and -independent DNA Polymerases

Development of technology for the construction of heat-efficient monolithic vaults from basalt fiber concrete

Peptide-conjugated antimiRs improve myotonic dystrophy type 1 phenotypes by promoting endogenous MBNL1 expression

2‘-O-Methyl-RNA Hairpins Generate Loop−Loop Complexes and Selectively Inhibit HIV-1 Tat-Mediated Transcription

Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription

Hexitol Nucleic Acid-Containing Aptamers Are Efficient Ligands of HIV-1 TAR RNA

Inhibition of HIV-1 Replication by Oligonucleotide Analogues Directed to the Packaging Signal and Trans-Activating Response Region

Loop-Loop Interaction of HIV-1 TAR RNA with N3t' → P5′ Deoxyphosphoramidate Aptamers Inhibits in vitro Tat-Mediated Transcription

Oligonucleotide inhibition of the interaction of HIV-1 Tat protein with the trans-activation responsive region (TAR) of HIV RNA

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