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Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P 4) receptor antagonists

Bioorganic & medicinal chemistry letters, 2011-06, Vol.21 (12), p.3632-3636

2011

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Discovery, design and synthesis of a selective S1P3 receptor allosteric agonist

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6346-6349

2013

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Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.537-542

2012

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SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.614-619

2013

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Discovery, synthesis and SAR analysis of novel selective small molecule S1P 4-R agonists based on a (2 Z,5 Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chemotype

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6739-6745

2011

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Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.839-843

2013

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Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.839-843

2013

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SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P4) receptor

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5470-5474

2011

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Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6346

2013

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Triazoles as γ-secretase modulators

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (13), p.4083-4087

2011

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Potent benzoazepinone γ-secretase modulators with improved bioavailability

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3495-3500

2015

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Discovery, synthesis and SAR analysis of novel selective small molecule S1P₄-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chemotype

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6739-6745

2011

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Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2254-2258

2010

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Discovery, synthesis and SAR analysis of novel selective small molecule S1P sub(4-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolid i n-4-one chemotype)

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6739-6745

2011

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Antagonists of the kappa opioid receptor

Bioorganic & medicinal chemistry letters, 2014-05, Vol.24 (9), p.2021-2032

2014

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A benzo[b]thiophene-based selective type 4 S1P receptor agonist

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (1), p.1-5

2017

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1-Sulfonyl-6-Piperazinyl-7-Azaindoles as potent and pseudo-selective 5-HT6 receptor antagonists

Bioorganic & medicinal chemistry letters, 2016-06, Vol.26 (11), p.2610-2615

2016

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Discovery of C-imidazole azaheptapyridine FPT inhibitors

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1134-1136

2010

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Triazoloamides as potent γ-secretase modulators with reduced hERG liability

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (9), p.3140-3146

2012

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1,3-Diaminopropan-2-ol Sulfonamides as potent and selective inhibitors of the glycine transporter type 1

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (6), p.1741-1745

2007

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Design and synthesis of conformationally constrained 3-( N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors

Bioorganic & medicinal chemistry letters, 2004-10, Vol.14 (19), p.4861-4866

2004

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Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.285-290

1999

Volltextzugriff (PDF)

Identification of (−)- cis-6-acetyl-4 S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2 H-benzo[b]pyran-3 S-ol as a potential antimigraine agent

Bioorganic & medicinal chemistry letters, 1999, Vol.9 (2), p.285-290

1999

Volltextzugriff (PDF)

Lanostane triterpenes from Ganoderma lucidum suppress the adipogenesis in 3T3-L1 cells through down-regulation of SREBP-1c

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5577-5581

2010

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Discovery of novel S1P2 antagonists. Part 2: Improving the profile of a series of 1,3-bis(aryloxy)benzene derivatives

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (20), p.4387-4392

2015

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1 – 25 von 26

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KollektionTaylor & Francis:Master (3349 titles)

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Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P 4) receptor antagonists

Discovery, design and synthesis of a selective S1P3 receptor allosteric agonist

Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists

Discovery, synthesis and SAR analysis of novel selective small molecule S1P 4-R agonists based on a (2 Z,5 Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chemotype

Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A2

Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A

SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P4) receptor

Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist

Triazoles as γ-secretase modulators

Potent benzoazepinone γ-secretase modulators with improved bioavailability

Discovery, synthesis and SAR analysis of novel selective small molecule S1P₄-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chemotype

Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9)

Discovery, synthesis and SAR analysis of novel selective small molecule S1P sub(4-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolid i n-4-one chemotype)

Antagonists of the kappa opioid receptor

A benzo[b]thiophene-based selective type 4 S1P receptor agonist

1-Sulfonyl-6-Piperazinyl-7-Azaindoles as potent and pseudo-selective 5-HT6 receptor antagonists

Discovery of C-imidazole azaheptapyridine FPT inhibitors

Triazoloamides as potent γ-secretase modulators with reduced hERG liability

1,3-Diaminopropan-2-ol Sulfonamides as potent and selective inhibitors of the glycine transporter type 1

Design and synthesis of conformationally constrained 3-( N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors

Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Identification of (−)- cis-6-acetyl-4 S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2 H-benzo[b]pyran-3 S-ol as a potential antimigraine agent

Lanostane triterpenes from Ganoderma lucidum suppress the adipogenesis in 3T3-L1 cells through down-regulation of SREBP-1c

Discovery of novel S1P2 antagonists. Part 2: Improving the profile of a series of 1,3-bis(aryloxy)benzene derivatives

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