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Immunogenicity of therapeutic proteins: Influence of aggregation

Journal of immunotoxicology, 2014-04, Vol.11 (2), p.99-109

2014

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Mechanistic Applicability Domain Classification of a Local Lymph Node Assay Dataset for Skin Sensitization

Chemical research in toxicology, 2007-07, Vol.20 (7), p.1019-1030

2007

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Chemical respiratory allergy: Reverse engineering an adverse outcome pathway

Toxicology (Amsterdam), 2014-04, Vol.318, p.32-39

2014

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The effect of arginine glutamate on the stability of monoclonal antibodies in solution

International journal of pharmaceutics, 2014-10, Vol.473 (1-2), p.126-133

2014

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Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

Pharmaceutical research, 2019-04, Vol.36 (4), p.51-14, Article 51

2019

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The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development

PloS one, 2014-09, Vol.9 (9), p.e106955

2014

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Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model

Journal of immunotoxicology, 2022-12, Vol.19 (1), p.1-7

2022

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Investigating Liquid–Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl

Molecular pharmaceutics, 2017-08, Vol.14 (8), p.2852-2860

2017

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The direct peptide reactivity assay: selectivity of chemical respiratory allergens

Toxicological sciences, 2012-10, Vol.129 (2), p.421-431

2012

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Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals

Methods (San Diego, Calif.), 2007, Vol.41 (1), p.54-60

2007

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Surrogate CD16-expressing effector cell lines for determining the bioactivity of therapeutic monoclonal antibodies

Journal of pharmaceutical and biomedical analysis, 2017-09, Vol.143, p.188-198

2017

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Human neutrophil antigens: Nature, clinical significance and detection

International journal of immunogenetics, 2021-04, Vol.48 (2), p.145-156

2021

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The lymphocyte transformation test in allergic contact dermatitis: New opportunities

Journal of immunotoxicology, 2016-01, Vol.13 (1), p.84-91

2016

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Anti-hapten antibodies in response to skin sensitization

Contact dermatitis, 2016-04, Vol.74 (4), p.197-204

2016

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The IgE-facilitated allergen binding (FAB) assay: Validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses

Journal of immunological methods, 2006-12, Vol.317 (1), p.71-79

2006

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Chemical reactivity measurements: Potential for characterization of respiratory chemical allergens

Toxicology in vitro, 2011-03, Vol.25 (2), p.433-445

2011

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Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization

Journal of immunotoxicology, 2013-07, Vol.10 (3), p.223-234

2013

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Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease

Clinics in dermatology, 2011-05, Vol.29 (3), p.257-265

2011

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Dose metrics in the acquisition of skin sensitization: Thresholds and importance of dose per unit area

Regulatory toxicology and pharmacology, 2008-10, Vol.52 (1), p.39-45

2008

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Chemical allergy: translating biology into hazard characterization

Toxicological sciences, 2011-03, Vol.120 Suppl 1 (Supplement 1), p.S238-S268

2011

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Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment

Toxicological sciences, 2019-07, Vol.170 (1), p.210-222

2019

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The selective peptide reactivity of chemical respiratory allergens under competitive and non-competitive conditions

Journal of immunotoxicology, 2013-07, Vol.10 (3), p.292-301

2013

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Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin

Immunology, 2018-01, Vol.153 (1), p.60-70

2018

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T lymphocyte dynamics in methylisothiazolinone-allergic patients

Contact dermatitis, 2016-07, Vol.75 (1), p.1-13

2016

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Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization

Journal of applied toxicology, 2014-10, Vol.34 (10), p.1073-1077

2014

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Immunogenicity of therapeutic proteins: Influence of aggregation

Mechanistic Applicability Domain Classification of a Local Lymph Node Assay Dataset for Skin Sensitization

Chemical respiratory allergy: Reverse engineering an adverse outcome pathway

The effect of arginine glutamate on the stability of monoclonal antibodies in solution

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies

The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development

Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model

Investigating Liquid–Liquid Phase Separation of a Monoclonal Antibody Using Solution-State NMR Spectroscopy: Effect of Arg·Glu and Arg·HCl

The direct peptide reactivity assay: selectivity of chemical respiratory allergens

Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals

Surrogate CD16-expressing effector cell lines for determining the bioactivity of therapeutic monoclonal antibodies

Human neutrophil antigens: Nature, clinical significance and detection

The lymphocyte transformation test in allergic contact dermatitis: New opportunities

Anti-hapten antibodies in response to skin sensitization

The IgE-facilitated allergen binding (FAB) assay: Validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses

Chemical reactivity measurements: Potential for characterization of respiratory chemical allergens

Danger, intracellular signaling, and the orchestration of dendritic cell function in skin sensitization

Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease

Dose metrics in the acquisition of skin sensitization: Thresholds and importance of dose per unit area

Chemical allergy: translating biology into hazard characterization

Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment

The selective peptide reactivity of chemical respiratory allergens under competitive and non-competitive conditions

Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin

T lymphocyte dynamics in methylisothiazolinone-allergic patients

Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization

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