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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Nature communications, 2024-03, Vol.15 (1), p.2612-2612

2024

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Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling

Chemico-biological interactions, 2024-05, Vol.394, p.110968-110968, Article 110968

2024

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PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures

Neoplasia (New York, N.Y.), 2024-05, Vol.51, p.100987-100987, Article 100987

2024

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The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

Cell biochemistry and function, 2024-04, Vol.42 (3), p.e3998-n/a

2024

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PI3Kγδ inhibition suppresses key disease features in a rat model of asthma

Respiratory research, 2024-04, Vol.25 (1), p.175-175

2024

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A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia

Journal of ethnopharmacology, 2024-06, Vol.328, p.118117-118117, Article 118117

2024

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Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells

PloS one, 2024-03, Vol.19 (3), p.e0300051-e0300051

2024

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Regulation of optimized new Shengmai powder on cardiomyocyte apoptosis and ferroptosis in ischemic heart failure rats: The mediating role of phosphatidylinositol-3-kinase/protein kinase B/tumor protein 53 signaling pathway

Journal of ethnopharmacology, 2024-08, Vol.330, p.118264-118264, Article 118264

2024

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LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway

Zhong hua yi xue za zhi, 2024-03, Vol.104 (10), p.758-765

2024

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Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Archivos españoles de urología, 2024-03, Vol.77 (2), p.183-192

2024

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Plasmodium falciparum selectively degrades α-spectrin of infected erythrocytes after invasion

mBio, 2024-04, Vol.15 (4), p.e0351023-e0351023

2024

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Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

Journal of integrative neuroscience, 2024-03, Vol.23 (3), p.61

2024

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miR-30a-5p attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis by regulating PTEN protein expression and activating PI3K/Akt signaling pathway

BMC cardiovascular disorders, 2024-05, Vol.24 (1), p.236-236

2024

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Effects of electroacupuncture on the PI3K/Akt/CREB signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats

Zhēncì yánjiū, 2024-03, Vol.49 (3), p.265

2024

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SPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE -/- mice

BMC cardiovascular disorders, 2024-05, Vol.24 (1), p.275-275

2024

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Hispidin Increases Cell Apoptosis and Ferroptosis in Prostate Cancer Cells Through Phosphatidylinositol-3-Kinase and Mitogen-activated Protein Kinase Signaling Pathway

Anticancer research, 2024-06, Vol.44 (6), p.2533

2024

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PI3Kγ inhibition combined with DNA vaccination unleashes a B-cell-dependent antitumor immunity that hampers pancreatic cancer

Journal of experimental & clinical cancer research, 2024-06, Vol.43 (1), p.157-157

2024

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Sevoflurane postconditioning attenuates cardiomyocytes hypoxia/reoxygenation injury via PI3K/AKT pathway mediated HIF-1α to regulate the mitochondrial dynamic balance

BMC cardiovascular disorders, 2024-05, Vol.24 (1), p.280-280

2024

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Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2024-02, Vol.75 (1)

2024

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Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based approach

International journal of biological macromolecules, 2024-05, Vol.266 (Pt 1), p.130912-130912, Article 130912

2024

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Inhibition of phosphoinositide 3-kinase activity attenuates neutrophilic airway inflammation and inhibits pyrin domain-containing 3 inflammasome activation in an ovalbumin-lipopolysaccharide-induced asthma murine model

Molecular biology reports, 2024-05, Vol.51 (1), p.698-698

2024

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PI 3-Kinase and the Histone Methyl-Transferase KMT2D Collaborate to Induce Arp2/3-Dependent Migration of Mammary Epithelial Cells

Cells (Basel, Switzerland), 2024-05, Vol.13 (10), p.876

2024

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A Phase I Study of the Oral Dual-Acting Pan-PI3K/mTOR Inhibitor Bimiralisib in Patients with Advanced Solid Tumors

Cancers, 2024-03, Vol.16 (6), p.1137

2024

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UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation

BMC cancer, 2024-04, Vol.24 (1), p.497-497

2024

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Regulation of inflammatory response by LINC00346 via miR-25-3p-mediated modulation of the PTEN/PI3K/AKT/NF-κB pathway

Biochemical and biophysical research communications, 2024-05, Vol.709, p.149828-149828, Article 149828

2024

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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling

PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures

The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

PI3Kγδ inhibition suppresses key disease features in a rat model of asthma

A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia

Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells

Regulation of optimized new Shengmai powder on cardiomyocyte apoptosis and ferroptosis in ischemic heart failure rats: The mediating role of phosphatidylinositol-3-kinase/protein kinase B/tumor protein 53 signaling pathway

LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway

Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Plasmodium falciparum selectively degrades α-spectrin of infected erythrocytes after invasion

Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

miR-30a-5p attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis by regulating PTEN protein expression and activating PI3K/Akt signaling pathway

Effects of electroacupuncture on the PI3K/Akt/CREB signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats

SPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE -/- mice

Hispidin Increases Cell Apoptosis and Ferroptosis in Prostate Cancer Cells Through Phosphatidylinositol-3-Kinase and Mitogen-activated Protein Kinase Signaling Pathway

PI3Kγ inhibition combined with DNA vaccination unleashes a B-cell-dependent antitumor immunity that hampers pancreatic cancer

Sevoflurane postconditioning attenuates cardiomyocytes hypoxia/reoxygenation injury via PI3K/AKT pathway mediated HIF-1α to regulate the mitochondrial dynamic balance

Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based approach

Inhibition of phosphoinositide 3-kinase activity attenuates neutrophilic airway inflammation and inhibits pyrin domain-containing 3 inflammasome activation in an ovalbumin-lipopolysaccharide-induced asthma murine model

PI 3-Kinase and the Histone Methyl-Transferase KMT2D Collaborate to Induce Arp2/3-Dependent Migration of Mammary Epithelial Cells

A Phase I Study of the Oral Dual-Acting Pan-PI3K/mTOR Inhibitor Bimiralisib in Patients with Advanced Solid Tumors

UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation

Regulation of inflammatory response by LINC00346 via miR-25-3p-mediated modulation of the PTEN/PI3K/AKT/NF-κB pathway

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