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Interrogating Estrogen Signaling Pathways in Human ER-Positive Breast Cancer Cells Forming Bone Metastases in Mice

Endocrinology (Philadelphia), 2024-04, Vol.165 (6)

2024

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Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer

Breast cancer research : BCR, 2020-11, Vol.22 (1), p.126-126, Article 126

2020

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Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer

British journal of cancer, 2019-10, Vol.121 (9), p.776-785

2019

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Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)—PathIES

Breast cancer research and treatment, 2019-05, Vol.175 (1), p.149-163

2019

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Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis

Breast cancer research and treatment, 2016-09, Vol.159 (2), p.215-227

2016

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Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer

Breast cancer research and treatment, 2015-04, Vol.150 (3), p.511-522

2015

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Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

Nature (London), 2012-01, Vol.481 (7381), p.389-393

2012

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The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells

Breast cancer research and treatment, 2011-06, Vol.127 (2), p.385-396

2011

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Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

Nature, 2008-12, Vol.456 (7222), p.663-666

2008

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Phosphorylation of Estrogen Receptor-α at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients

Clinical cancer research, 2007-10, Vol.13 (19), p.5769-5776

2007

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The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

Carcinogenesis (New York), 2004-12, Vol.25 (12), p.2509-2517

2004

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Estrogen receptors and anti-estrogen therapies

Cancer treatment and research, 2004, Vol.119, p.271

2004

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Reporter gene assay demonstrates functional differences in estrogen receptor activity in purified breast cancer cells: A pilot study

International journal of cancer, 2003-12, Vol.107 (5), p.700-706

2003

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T:G Mismatch-specific Thymine-DNA Glycosylase Potentiates Transcription of Estrogen-regulated Genes through Direct Interaction with Estrogen Receptor α

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38586-38592

2003

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Enhanced Estrogen Receptor (ER) α, ERBB2, and MAPK Signal Transduction Pathways Operate during the Adaptation of MCF-7 Cells to Long Term Estrogen Deprivation

The Journal of biological chemistry, 2003-08, Vol.278 (33), p.30458-30468

2003

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Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

The Journal of steroid biochemistry and molecular biology, 2002-08, Vol.81 (4), p.333-341

2002

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Phosphorylation of human estrogen receptor α at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera

Oncogene, 2002-07, Vol.21 (32), p.4921-4931

2002

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Endocrine-responsive breast cancer and strategies for combating resistance

Nature reviews. Cancer, 2002-02, Vol.2 (2), p.101-112

2002

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

The Journal of biological chemistry, 2001-03, Vol.276 (13), p.9817-9824

2001

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Activation of Estrogen Receptor α by S118 Phosphorylation Involves a Ligand-Dependent Interaction with TFIIH and Participation of CDK7

Molecular cell, 2000-07, Vol.6 (1), p.127-137

2000

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Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization

Molecular and Cellular Biology, 1999-02, Vol.19 (2), p.1002-1015

1999

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Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α

The Journal of biological chemistry, 1997-10, Vol.272 (41), p.25832-25838

1997

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Modulation of transcriptional activation by ligand‐dependent phosphorylation of the human oestrogen receptor A/B region

The EMBO journal, 1993-03, Vol.12 (3), p.1153-1160

1993

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Different TBP-associated factors are required for mediating the stimulation of transcription in vitro by the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor

Nucleic acids research, 1993-01, Vol.21 (1), p.5-12

1993

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Interrogating Estrogen Signaling Pathways in Human ER-Positive Breast Cancer Cells Forming Bone Metastases in Mice

Activating transcription factor-2 (ATF2) is a key determinant of resistance to endocrine treatment in an in vitro model of breast cancer

Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer

Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)—PathIES

Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis

Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

The liver receptor homolog-1 regulates estrogen receptor expression in breast cancer cells

Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

Phosphorylation of Estrogen Receptor-α at Ser167 Is Indicative of Longer Disease-Free and Overall Survival in Breast Cancer Patients

The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

Estrogen receptors and anti-estrogen therapies

Reporter gene assay demonstrates functional differences in estrogen receptor activity in purified breast cancer cells: A pilot study

T:G Mismatch-specific Thymine-DNA Glycosylase Potentiates Transcription of Estrogen-regulated Genes through Direct Interaction with Estrogen Receptor α

Enhanced Estrogen Receptor (ER) α, ERBB2, and MAPK Signal Transduction Pathways Operate during the Adaptation of MCF-7 Cells to Long Term Estrogen Deprivation

Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

Phosphorylation of human estrogen receptor α at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera

Endocrine-responsive breast cancer and strategies for combating resistance

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

Activation of Estrogen Receptor α by S118 Phosphorylation Involves a Ligand-Dependent Interaction with TFIIH and Participation of CDK7

Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization

Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α

Modulation of transcriptional activation by ligand‐dependent phosphorylation of the human oestrogen receptor A/B region

Different TBP-associated factors are required for mediating the stimulation of transcription in vitro by the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor

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