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Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

Journal of medicinal chemistry, 2015-12, Vol.58 (23), p.9334-9344

2015

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Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots

Journal of pharmaceutical and biomedical analysis, 2016-04, Vol.122, p.16-20

2016

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Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents

Chemico-biological interactions, 2016-11, Vol.259 (Pt B), p.133-141

2016

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Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes

International journal of pharmaceutics, 2008-09, Vol.361 (1), p.104-111

2008

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Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin

Bioorganic & medicinal chemistry, 2015-12, Vol.23 (24), p.7529-7534

2015

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Design, Synthesis, and Preclinical Evaluation of New 5,6- (or 6,7-) Disubstituted-2-(fluorophenyl)quinolin-4-one Derivatives as Potent Antitumor Agents

Journal of medicinal chemistry, 2010-11, Vol.53 (22), p.8047-8058

2010

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Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01

ACS chemical neuroscience, 2012-06, Vol.3 (6), p.451-458

2012

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Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer

Journal of medicinal chemistry, 2005-08, Vol.48 (16), p.5373-5377

2005

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RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment

Journal of controlled release, 2012-06, Vol.160 (2), p.177-181

2012

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Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450

European journal of pharmaceutical sciences, 2015-06, Vol.73, p.49-56

2015

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Antineoplastic Agents. 465. Structural Modification of Resveratrol: Sodium Resverastatin Phosphate

Journal of medicinal chemistry, 2002-06, Vol.45 (12), p.2534-2542

2002

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Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C

Marine Drugs, 2010-01, Vol.8 (1), p.122-172

2010

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Structural and immunostimulatory properties of Y-shaped DNA consisting of phosphodiester and phosphorothioate oligodeoxynucleotides

Journal of controlled release, 2010-12, Vol.148 (3), p.311-316

2010

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Enhancement of the transdermal delivery of catechins by liposomes incorporating anionic surfactants and ethanol

International journal of pharmaceutics, 2006-03, Vol.310 (1), p.131-138

2006

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Influence of a niosomal formulation on the oral bioavailability of acyclovir in rabbits

AAPS PharmSciTech, 2007-10, Vol.8 (4), p.E106-212

2007

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Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells

Bioorganic & medicinal chemistry, 2004-12, Vol.12 (23), p.6097-6105

2004

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Tracking the dephosphorylation of resveratrol triphosphate in skin by confocal Raman microscopy

Journal of controlled release, 2007-11, Vol.123 (2), p.141-147

2007

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Systemic Delivery of Small Interfering RNA by Use of Targeted Polycation Liposomes for Cancer Therapy

Biological and Pharmaceutical Bulletin, 2013/02/01, Vol.36(2), pp.287-291

2013

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Duplex Formation of the Simplified Nucleic Acid GNA

Chembiochem : a European journal of chemical biology, 2007-05, Vol.8 (8), p.927-932

2007

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Ionic Liquids and Proteases: A Clean Alliance for Semisynthesis

Chembiochem : a European journal of chemical biology, 2008-06, Vol.9 (9), p.1493-1499

2008

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A Prodrug Approach toward the Development of Water Soluble Fluoroquinolones and Structure−Activity Relationships of Quinoline-3-carboxylic Acids

Journal of medicinal chemistry, 2004-09, Vol.47 (19), p.4693-4709

2004

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Uracil-Catalyzed Synthesis of Acetyl Phosphate: A Photochemical Driver for Protometabolism

Chembiochem : a European journal of chemical biology, 2010-02, Vol.11 (3), p.383-387

Hagan Jr, William J.

2010

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Fatty Alcohol Phosphates are Subtype-Selective Agonists and Antagonists of Lysophosphatidic Acid Receptors

Molecular pharmacology, 2003-05, Vol.63 (5), p.1032-1042

2003

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Development and validation of discriminating method of dissolution for fosamprenavir tablets based on in vivo data

Journal of pharmaceutical and biomedical analysis, 2011-02, Vol.54 (3), p.439-444

2011

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Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents

Journal of medicinal chemistry, 2002-05, Vol.45 (11), p.2185-2196

2002

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1 – 25 von 98

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Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots

Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents

Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes

Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin

Design, Synthesis, and Preclinical Evaluation of New 5,6- (or 6,7-) Disubstituted-2-(fluorophenyl)quinolin-4-one Derivatives as Potent Antitumor Agents

Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01

Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer

RGD-based active targeting of novel polycation liposomes bearing siRNA for cancer treatment

Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450

Antineoplastic Agents. 465. Structural Modification of Resveratrol: Sodium Resverastatin Phosphate

Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C

Structural and immunostimulatory properties of Y-shaped DNA consisting of phosphodiester and phosphorothioate oligodeoxynucleotides

Enhancement of the transdermal delivery of catechins by liposomes incorporating anionic surfactants and ethanol

Influence of a niosomal formulation on the oral bioavailability of acyclovir in rabbits

Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells

Tracking the dephosphorylation of resveratrol triphosphate in skin by confocal Raman microscopy

Systemic Delivery of Small Interfering RNA by Use of Targeted Polycation Liposomes for Cancer Therapy

Duplex Formation of the Simplified Nucleic Acid GNA

Ionic Liquids and Proteases: A Clean Alliance for Semisynthesis

A Prodrug Approach toward the Development of Water Soluble Fluoroquinolones and Structure−Activity Relationships of Quinoline-3-carboxylic Acids

Uracil-Catalyzed Synthesis of Acetyl Phosphate: A Photochemical Driver for Protometabolism

Fatty Alcohol Phosphates are Subtype-Selective Agonists and Antagonists of Lysophosphatidic Acid Receptors

Development and validation of discriminating method of dissolution for fosamprenavir tablets based on in vivo data

Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents

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