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CDK7 inhibitors as anticancer drugs

Cancer and metastasis reviews, 2020-09, Vol.39 (3), p.805-823

2020

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Light-triggered enzymatic reactions in nested vesicle reactors

Nature communications, 2018-03, Vol.9 (1), p.1093-6, Article 1093

2018

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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Nature communications, 2017-11, Vol.8 (1), p.1865-15, Article 1865

2017

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Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

Clinical cancer research, 2017-01, Vol.23 (1), p.88-96

2017

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The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

Scientific reports, 2017-11, Vol.7 (1), p.16115-12, Article 16115

2017

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Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

Nature communications, 2022-08, Vol.13 (1), p.4975-4975, Article 4975

2022

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Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

Oncogene, 2022-04, Vol.41 (15), p.2139-2151

2022

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ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Molecular cancer therapeutics, 2018-06, Vol.17 (6), p.1156-1166

2018

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Detection of Multiple Breast Cancer ESR1 Mutations on an ISFET Based Lab-on-Chip Platform

IEEE transactions on biomedical circuits and systems, 2021-06, Vol.15 (3), p.380-389

2021

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p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

Nucleic acids research, 2017-11, Vol.45 (19), p.11056-11069

2017

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A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

Scientific reports, 2020-03, Vol.10 (1), p.4553, Article 4553

2020

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Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB

Oncogene, 2021-02, Vol.40 (6), p.1077-1090

2021

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A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk

JNCI : Journal of the National Cancer Institute, 2013-04, Vol.105 (8), p.573-579

2013

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Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib

Nature communications, 2023-07, Vol.14 (1), p.4444-4444, Article 4444

2023

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Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes

PloS one, 2016-02, Vol.11 (2), p.e0147990

2016

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Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling

Scientific reports, 2024-03, Vol.14 (1), p.6873-6873, Article 6873

2024

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High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Nature communications, 2024-03, Vol.15 (1), p.2265-2265, Article 2265

2024

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The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo

Cancers, 2023-04, Vol.15 (8), p.2211

2023

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Distinguishing PIK3CA p.E545K Mutational Status from Pseudogene DNA with a Next-Generation ISFET Sensor Array

2023 IEEE International Symposium on Circuits and Systems (ISCAS), 2023, p.1-5

2023

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Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

Nature communications, 2019-08, Vol.10 (1), p.3505-1, Article 3505

2019

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The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation

Cancers, 2023-11, Vol.15 (22), p.5434

2023

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Author Correction: Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib

Nature communications, 2023-08, Vol.14 (1), p.4741-4741, Article 4741

2023

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Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer

Nature medicine, 2011-06, Vol.17 (6), p.715-719

2011

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Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer

Cancers, 2021-12, Vol.13 (24), p.6314

2021

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The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators

Biochemical Society transactions, 2008-08, Vol.36 (Pt 4), p.609-612

2008

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CDK7 inhibitors as anticancer drugs

Light-triggered enzymatic reactions in nested vesicle reactors

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Detection of Multiple Breast Cancer ESR1 Mutations on an ISFET Based Lab-on-Chip Platform

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation

Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB

A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk

Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib

Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes

Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo

Distinguishing PIK3CA p.E545K Mutational Status from Pseudogene DNA with a Next-Generation ISFET Sensor Array

Author Correction: Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation

Author Correction: Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib

Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer

Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer

The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators

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