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Inhibitors of HIV‑1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir

Journal of medicinal chemistry, 2018-01, Vol.61 (1), p.62-80

2018

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A novel in situ hydrophobic ion paring (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system

Journal of controlled release, 2016-05, Vol.229, p.106-119

2016

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Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin

Journal of natural products (Washington, D.C.), 2020-02, Vol.83 (2), p.461-467

2020

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Amiselimod, a novel sphingosine 1‐phosphate receptor‐1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk

British journal of pharmacology, 2017-01, Vol.174 (1), p.15-27

2017

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Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells

Chemical research in toxicology, 2019-06, Vol.32 (6), p.1250-1258

2019

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Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: Application of Box–Behnken design, in-vitro evaluation and in-vivo skin deposition study

International journal of pharmaceutics, 2015-05, Vol.485 (1-2), p.235-243

2015

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Dose-Dependent Molecular Responses of Labeo rohita to Triphenyl Phosphate

Chemical research in toxicology, 2021-12, Vol.34 (12), p.2500-2511

2021

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Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

Journal of medicinal chemistry, 2015-12, Vol.58 (23), p.9334-9344

2015

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Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to organophosphate esters (OPEs)

Toxicology and applied pharmacology, 2019-05, Vol.371, p.84-94

2019

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Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots

Journal of pharmaceutical and biomedical analysis, 2016-04, Vol.122, p.16-20

2016

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Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations

Toxicology (Amsterdam), 2018-08, Vol.406-407, p.104-113

2018

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Vapor Pressure and Toxicity Prediction for Novichok Agent Candidates Using Machine Learning Model: Preparation for Unascertained Nerve Agents after Chemical Weapons Convention Schedule 1 Update

Chemical research in toxicology, 2022-05, Vol.35 (5), p.774-781

2022

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Novel triclabendazole prodrug: A highly water soluble alternative for the treatment of fasciolosis

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (3), p.616-619

2017

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Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates

Chembiochem : a European journal of chemical biology, 2015-10, Vol.16 (15), p.2205-2215

2015

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Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells

Toxicology (Amsterdam), 2023-08, Vol.494, p.153588-153588, Article 153588

2023

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Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents

Chemico-biological interactions, 2016-11, Vol.259 (Pt B), p.133-141

2016

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Synthesis of xanthosine 2-phosphate diesters via phosphitylation of the carbonyl group

Bioorganic & medicinal chemistry letters, 2021-12, Vol.54, p.128439-128439, Article 128439

2021

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Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold

European journal of medicinal chemistry, 2019-12, Vol.184, p.111754, Article 111754

2019

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Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes

International journal of pharmaceutics, 2008-09, Vol.361 (1), p.104-111

2008

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Synthesis and in-vitro reactivation screening of imidazolium aldoximes as reactivators of sarin and VX-inhibited human acetylcholinesterase (hAChE)

Chemico-biological interactions, 2016-11, Vol.259 (Pt B), p.85-92

2016

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A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells

Biochemical pharmacology, 2015-09, Vol.97 (1), p.51-61

2015

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Synthesis and Characterization of a Phosphate Prodrug of Isoliquiritigenin

Journal of natural products (Washington, D.C.), 2017-04, Vol.80 (4), p.879-886

2017

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Synthesis of a 2‑Aryl-3-aroyl Indole Salt (OXi8007) Resembling Combretastatin A‑4 with Application as a Vascular Disrupting Agent

Journal of natural products (Washington, D.C.), 2013-09, Vol.76 (9), p.1668-1678

2013

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Synthesis, biochemical evaluation, and molecular modeling studies of aryl and arylalkyl di-n-butyl phosphates, effective butyrylcholinesterase inhibitors

Bioorganic & medicinal chemistry, 2017-06, Vol.25 (12), p.3171-3181

2017

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Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin

Bioorganic & medicinal chemistry, 2015-12, Vol.23 (24), p.7529-7534

2015

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Inhibitors of HIV‑1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir

A novel in situ hydrophobic ion paring (HIP) formulation strategy for clinical product selection of a nanoparticle drug delivery system

Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin

Amiselimod, a novel sphingosine 1‐phosphate receptor‐1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk

Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells

Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: Application of Box–Behnken design, in-vitro evaluation and in-vivo skin deposition study

Dose-Dependent Molecular Responses of Labeo rohita to Triphenyl Phosphate

Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to organophosphate esters (OPEs)

Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots

Oxime-assisted reactivation of tabun-inhibited acetylcholinesterase analysed by active site mutations

Vapor Pressure and Toxicity Prediction for Novichok Agent Candidates Using Machine Learning Model: Preparation for Unascertained Nerve Agents after Chemical Weapons Convention Schedule 1 Update

Novel triclabendazole prodrug: A highly water soluble alternative for the treatment of fasciolosis

Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates

Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells

Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents

Synthesis of xanthosine 2-phosphate diesters via phosphitylation of the carbonyl group

Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold

Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes

Synthesis and in-vitro reactivation screening of imidazolium aldoximes as reactivators of sarin and VX-inhibited human acetylcholinesterase (hAChE)

A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells

Synthesis and Characterization of a Phosphate Prodrug of Isoliquiritigenin

Synthesis of a 2‑Aryl-3-aroyl Indole Salt (OXi8007) Resembling Combretastatin A‑4 with Application as a Vascular Disrupting Agent

Synthesis, biochemical evaluation, and molecular modeling studies of aryl and arylalkyl di-n-butyl phosphates, effective butyrylcholinesterase inhibitors

Synthesis and comparison of the biological activity of monocyclic phosphonate, difluorophosphonate and phosphate analogs of the natural AChE inhibitor cyclophostin

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