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Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

Xenobiotica, 2009-01, Vol.39 (1), p.11-21

2009

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Microarray Analysis of the Global Alterations in the Gene Expression in the Placentas From Cigarette-smoking Mothers

Clinical pharmacology and therapeutics, 2008-04, Vol.83 (4), p.542-550

2008

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The expression and regulation of drug metabolism in human placenta

Advanced drug delivery reviews, 1999-06, Vol.38 (1), p.81-97

Pasanen, Markku

1999

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CYP2A6: a human coumarin 7-hydroxylase

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.139-147

2000

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Species variation in the response of the cytochrome P-450-dependent monooxygenase system to inducers and inhibitors

Xenobiotica, 1990, Vol.20 (11), p.1139-1161

1990

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Expression of xenobiotic-metabolizing cytochrome P450 Forms in human full-term placenta

Biochemical pharmacology, 1996-02, Vol.51 (4), p.403-411

1996

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Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy

Biochemical pharmacology, 1996-07, Vol.52 (2), p.379-383

1996

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Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver

Biochemical pharmacology, 1994-07, Vol.48 (1), p.59-64

1994

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Immunochemical and molecular biological studies on human placental cigarette smoke-inducible cytochrome P-450-dependent monooxygenase activities

Toxicology (Amsterdam), 1990-05, Vol.62 (2), p.175-187

1990

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Lack of association between CYP2A5 induction and apoptosis in mouse primary hepatocytes

Biochemical pharmacology, 2002-02, Vol.63 (3), p.429-435

2002

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Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice

Biochemical pharmacology, 1992-10, Vol.44 (7), p.1269-1274

1992

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Retrovirus-mediated stable expression of human CYP2A6 in mammalian cells

European journal of pharmacology, 1993-08, Vol.248 (2), p.95-102

1993

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A Convenient Laboratory Experiment for Teaching the Fundamentals of Drug Metabolism

American journal of pharmaceutical education, 1997, Vol.61 (3), p.314-317

1997

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Human Placental Xenobiotic and Steroid Biotransformations Catalyzed By Cytochrome P450, Epoxide Hydrolase, and Glutathione S-Transferase Activities and Their Relationships to Maternal Cigarette Smoking

Drug metabolism reviews, 1989, Vol.21 (3), p.427-461

1989

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Characterization of human fetal hepatic cytochrome P-450-associated 7-ethoxyresorufin O-deethylase and aryl hydrocarbon hydroxylase activities by monoclonal antibodies

Developmental pharmacology and therapeutics, 1987, Vol.10 (2), p.125

1987

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Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines

Chemico-biological interactions, 1988, Vol.66 (3), p.223-232

1988

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Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the Regulation Process

Pharmacology & toxicology, 1998-11, Vol.83 (5), p.183-187

1998

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Species-Specific Differences in the in Vitro Metabolism of Lasiocarpine

Chemical research in toxicology, 2015-10, Vol.28 (10), p.2034-2044

2015

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Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics

Pharmacogenetics and genomics, 2006-11, Vol.16 (11), p.801-808

2006

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In Silico Prediction of the Site of Oxidation by Cytochrome P450 3A4 That Leads to the Formation of the Toxic Metabolites of Pyrrolizidine Alkaloids

Chemical research in toxicology, 2015-04, Vol.28 (4), p.702-710

2015

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Identification of a New Reactive Metabolite of Pyrrolizidine Alkaloid Retrorsine: (3H‑Pyrrolizin-7-yl)methanol

Chemical research in toxicology, 2014-11, Vol.27 (11), p.1950-1957

2014

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Tricaine (MS‐222) Induced Modification on the Metabolism of Foreign Compounds in the Liver and Duodenal Mucosa of the Splake (Salvelinus fontinalis X Salvelinus namaycush)

Acta pharmacologica et toxicologica, 1981-08, Vol.49 (2), p.92-97

1981

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Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

Microarray Analysis of the Global Alterations in the Gene Expression in the Placentas From Cigarette-smoking Mothers

The expression and regulation of drug metabolism in human placenta

CYP2A6: a human coumarin 7-hydroxylase

Species variation in the response of the cytochrome P-450-dependent monooxygenase system to inducers and inhibitors

Expression of xenobiotic-metabolizing cytochrome P450 Forms in human full-term placenta

Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy

Expression of xenobiotic-metabolizing cytochrome P450 forms in human adult and fetal liver

Immunochemical and molecular biological studies on human placental cigarette smoke-inducible cytochrome P-450-dependent monooxygenase activities

Lack of association between CYP2A5 induction and apoptosis in mouse primary hepatocytes

Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice

Retrovirus-mediated stable expression of human CYP2A6 in mammalian cells

A Convenient Laboratory Experiment for Teaching the Fundamentals of Drug Metabolism

Human Placental Xenobiotic and Steroid Biotransformations Catalyzed By Cytochrome P450, Epoxide Hydrolase, and Glutathione S-Transferase Activities and Their Relationships to Maternal Cigarette Smoking

Characterization of human fetal hepatic cytochrome P-450-associated 7-ethoxyresorufin O-deethylase and aryl hydrocarbon hydroxylase activities by monoclonal antibodies

Induction of cytochrome P-450IA1 gene expression in human breast tumour cell lines

Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the Regulation Process

Species-Specific Differences in the in Vitro Metabolism of Lasiocarpine

Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics

In Silico Prediction of the Site of Oxidation by Cytochrome P450 3A4 That Leads to the Formation of the Toxic Metabolites of Pyrrolizidine Alkaloids

Identification of a New Reactive Metabolite of Pyrrolizidine Alkaloid Retrorsine: (3H‑Pyrrolizin-7-yl)methanol

Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human clinical trials

Tricaine (MS‐222) Induced Modification on the Metabolism of Foreign Compounds in the Liver and Duodenal Mucosa of the Splake (Salvelinus fontinalis X Salvelinus namaycush)

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