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Running on time: the role of circadian clocks in the musculoskeletal system

Biochemical journal, 2014-10, Vol.463 (1), p.1-8

2014

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Tissue physiology revolving around the clock: circadian rhythms as exemplified by the intervertebral disc

Annals of the rheumatic diseases, 2021-07, Vol.80 (7), p.828-839

2021

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Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment

Journal of cell science, 2018-03, Vol.131 (5), p.jcs208223-jcs208223

2018

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Lithium impacts on the amplitude and period of the molecular circadian clockwork

PloS one, 2012-03, Vol.7 (3), p.e33292-e33292

2012

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The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

Arthritis & rheumatology (Hoboken, N.J.), 2013-09, Vol.65 (9), p.2334-2345

2013

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Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

PloS one, 2023-01, Vol.18 (1), p.e0280024-e0280024

2023

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Cellular mechano-environment regulates the mammary circadian clock

Nature communications, 2017-01, Vol.8 (1), p.14287-14287, Article 14287

2017

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The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

The Journal of clinical investigation, 2016-01, Vol.126 (1), p.365-376

2016

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The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

Nucleic acids research, 2014-05, Vol.42 (9), p.5765-5775

2014

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Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

PLoS genetics, 2020-04, Vol.16 (4), p.e1008729-e1008729

2020

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Circadian rhythms in skin and other elastic tissues

Matrix biology, 2019-11, Vol.84, p.97-110

2019

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Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

Journal of cellular physiology, 2015-09, Vol.230 (9), p.2174-2183

2015

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Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks

Nature communications, 2023-11, Vol.14 (1), p.7237-7237, Article 7237

2023

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Meteorin-like protein/METRNL/Interleukin-41 ameliorates atopic dermatitis-like inflammation

Allergy (Copenhagen), 2024-05

2024

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Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15240-15245

2010

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Tick tock, the cartilage clock

Osteoarthritis and cartilage, 2023-11, Vol.31 (11), p.1425-1436

2023

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Knockdown of cytokeratin 8 overcomes chemoresistance of chordoma cells by aggravating endoplasmic reticulum stress through PERK/eIF2α arm of unfolded protein response and blocking autophagy

Cell death & disease, 2019-11, Vol.10 (12), p.887-18, Article 887

2019

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Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration

Bone Research, 2022-02, Vol.10 (1), p.20-20, Article 20

2022

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Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model

Theranostics, 2022, Vol.12 (8), p.3963-3976

2022

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Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

eLife, 2022-03, Vol.11

2022

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Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

Current biology, 2016-07, Vol.26 (14), p.1880-1886

2016

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Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease

Cells (Basel, Switzerland), 2023-06, Vol.12 (12), p.1582

2023

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The brain-joint axis in osteoarthritis: nerves, circadian clocks and beyond

Nature reviews. Rheumatology, 2016-09, Vol.12 (9), p.508-516

2016

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Delayed elimination communication on the prevalence of children's bladder and bowel dysfunction

Scientific reports, 2021-06, Vol.11 (1), p.12366-12366, Article 12366

2021

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Running on time: the role of circadian clocks in the musculoskeletal system

Tissue physiology revolving around the clock: circadian rhythms as exemplified by the intervertebral disc

Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment

Lithium impacts on the amplitude and period of the molecular circadian clockwork

The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

Cellular mechano-environment regulates the mammary circadian clock

The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

Macromolecular condensation buffers intracellular water potential

The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

Circadian rhythms in skin and other elastic tissues

Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks

Meteorin-like protein/METRNL/Interleukin-41 ameliorates atopic dermatitis-like inflammation

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Tick tock, the cartilage clock

Knockdown of cytokeratin 8 overcomes chemoresistance of chordoma cells by aggravating endoplasmic reticulum stress through PERK/eIF2α arm of unfolded protein response and blocking autophagy

Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration

Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model

Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

Circadian Disruption Primes Myofibroblasts for Accelerated Activation as a Mechanism Underpinning Fibrotic Progression in Non-Alcoholic Fatty Liver Disease

The brain-joint axis in osteoarthritis: nerves, circadian clocks and beyond

Delayed elimination communication on the prevalence of children's bladder and bowel dysfunction

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