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Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
The Lancet (British edition), 2020-05, Vol.395 (10236), p.1569-1578
2020
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Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial
The Lancet (British edition), 2020-12, Vol.396 (10265), p.1817-1828
2020
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Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Nature medicine, 2021-10, Vol.27 (10), p.1752-1760
2021
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Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase 3 trial
The Lancet (British edition), 2020-10, Vol.396 (10257), p.1090-1100
2020
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Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials
The Lancet (British edition), 2019-11, Vol.394 (10209), p.1638-1650
2019
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Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind, placebo-controlled, phase 3 trial
The lancet oncology, 2020-01, Vol.21 (1), p.44-59
2020
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Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial
The Lancet (British edition), 2021-07, Vol.398 (10295), p.143-155
2021
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Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet (British edition), 2020-09, Vol.396 (10253), p.759-769
2020
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Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study
The lancet oncology, 2020-06, Vol.21 (6), p.796-807
2020
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Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled, phase 3 trial
The lancet oncology, 2019-02, Vol.20 (2), p.282-296
2019
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Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial
The Lancet (British edition), 2020-12, Vol.396 (10266), p.1895-1904
2020
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Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
The Lancet (British edition), 2018-10, Vol.392 (10157), p.1519-1529
2018
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Nivolumab plus chemotherapy versus placebo plus chemotherapy in patients with HER2-negative, untreated, unresectable advanced or recurrent gastric or gastro-oesophageal junction cancer (ATTRACTION-4): a randomised, multicentre, double-blind, placebo-controlled, phase 3 trial
The lancet oncology, 2022-02, Vol.23 (2), p.234-247
2022
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Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet (British edition), 2023-06, Vol.401 (10391), p.1853-1865
2023
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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA): end-of-study results from a double-blind, randomised, placebo-controlled, phase 3 study
The lancet oncology, 2020-04, Vol.21 (4), p.519-530
2020
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Pembrolizumab versus placebo as adjuvant therapy in completely resected stage IIB or IIC melanoma (KEYNOTE-716): a randomised, double-blind, phase 3 trial
The Lancet (British edition), 2022-04, Vol.399 (10336), p.1718-1729
2022
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Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study
The Lancet (British edition), 2022-04, Vol.399 (10333), p.1383-1390
2022
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Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
The Lancet (British edition), 2021-03, Vol.397 (10278), p.971-984
2021
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Once-daily upadacitinib versus placebo in adolescents and adults with moderate-to-severe atopic dermatitis (Measure Up 1 and Measure Up 2): results from two replicate double-blind, randomised controlled phase 3 trials
The Lancet (British edition), 2021-06, Vol.397 (10290), p.2151-2168
2021
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Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet (British edition), 2017-10, Vol.390 (10106), p.1949-1961
2017
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Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial
The lancet oncology, 2021-04, Vol.22 (4), p.450-462
2021
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Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
The Lancet (British edition), 2020-03, Vol.395 (10227), p.878-887
2020
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Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial
The lancet oncology, 2019-12, Vol.20 (12), p.1655-1669
2019
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Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial
The lancet oncology, 2019-05, Vol.20 (5), p.686-700
2019
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Adjuvant nivolumab versus ipilimumab in resected stage IIIB–C and stage IV melanoma (CheckMate 238): 4-year results from a multicentre, double-blind, randomised, controlled, phase 3 trial
The lancet oncology, 2020-11, Vol.21 (11), p.1465-1477
2020
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