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Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

Journal of antimicrobial chemotherapy, 2014-10, Vol.69 (10), p.2770-2784

2014

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Mutations on VEEV nsP1 relate RNA capping efficiency to ribavirin susceptibility

Antiviral research, 2020-10, Vol.182, p.104883-104883, Article 104883

2020

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Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Antimicrobial agents and chemotherapy, 2020-06, Vol.64 (7)

2020

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Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

Antiviral research, 2017-08, Vol.144, p.330-339

2017

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Implementation of a non-human primate model of Ebola disease: Infection of Mauritian cynomolgus macaques and analysis of virus populations

Antiviral research, 2017-04, Vol.140, p.95-105

2017

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Approved drugs screening against the nsP1 capping enzyme of Venezuelan equine encephalitis virus using an immuno-based assay

Antiviral research, 2019-03, Vol.163, p.59-69

2019

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Bunyaviridae RdRps: structure, motifs, and RNA synthesis machinery

Critical reviews in microbiology, 2017-11, Vol.43 (6), p.753-778

2017

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Uracil within DNA: an actor of antiviral immunity

Retrovirology, 2008-06, Vol.5 (1), p.45-45, Article 45

2008

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Phylogenetically based establishment of a dengue virus panel, representing all available genotypes, as a tool in dengue drug discovery

Antiviral research, 2019-08, Vol.168, p.109-113

2019

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Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors

European journal of medicinal chemistry, 2019-01, Vol.161 (4), p.323-333

2019

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Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons

Journal of general virology, 2014-11, Vol.95 (Pt 11), p.2462-2467

2014

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Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling

Virology (New York, N.Y.), 2010-09, Vol.404 (2), p.319-330

2010

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Functional Role of HIV-1 Virion-associated Uracil DNA Glycosylase 2 in the Correction of G:U Mispairs to G:C Pairs

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.4566-4571

2003

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Visna Virus dUTPase Is Dispensable for Neuropathogenicity

Journal of Virology, 1998-02, Vol.72 (2), p.1657-1661

1998

Volltextzugriff (PDF)

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

European journal of medicinal chemistry, 2017-01, Vol.125, p.865-880

2017

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A novel class of small molecule inhibitors targeting the chikungunya virus capping machinery with a high barrier to resistance

Access microbiology, 2019-12, Vol.1 (10)

2019

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HIV-1-Associated Uracil DNA Glycosylase Activity Controls dUTP Misincorporation in Viral DNA and Is Essential to the HIV-1 Life Cycle

Molecular cell, 2005-02, Vol.17 (4), p.479-490

2005

Volltextzugriff (PDF)

A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction

Nature (London), 2021-10, Vol.598 (7881), p.504-509

2021

Volltextzugriff (PDF)

Toscana virus cap-snatching and initiation of transcription

Journal of general virology, 2017-11, Vol.98 (11), p.2676-2688

2017

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Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

European journal of medicinal chemistry, 2016-02, Vol.109, p.146-156

2016

Volltextzugriff (PDF)

Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor

Antiviral research, 2016-10, Vol.134, p.226-235

2016

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Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

European journal of medicinal chemistry, 2018-01, Vol.143, p.1667-1676

2018

Volltextzugriff (PDF)

Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions

Antiviral research, 2019-07, Vol.167, p.6-12

2019

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Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1

Antiviral research, 2017-08, Vol.144, p.216-222

2017

Volltextzugriff (PDF)

Identification of [1,2,3]Triazolo[4,5‑d]pyrimidin-7(6H)‑ones as Novel Inhibitors of Chikungunya Virus Replication

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.4000-4008

2014

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Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

Mutations on VEEV nsP1 relate RNA capping efficiency to ribavirin susceptibility

Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

Implementation of a non-human primate model of Ebola disease: Infection of Mauritian cynomolgus macaques and analysis of virus populations

Approved drugs screening against the nsP1 capping enzyme of Venezuelan equine encephalitis virus using an immuno-based assay

Bunyaviridae RdRps: structure, motifs, and RNA synthesis machinery

Uracil within DNA: an actor of antiviral immunity

Phylogenetically based establishment of a dengue virus panel, representing all available genotypes, as a tool in dengue drug discovery

Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors

Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons

Nonstructural NS1 proteins of several mosquito-borne Flavivirus do not inhibit TLR3 signaling

Functional Role of HIV-1 Virion-associated Uracil DNA Glycosylase 2 in the Correction of G:U Mispairs to G:C Pairs

Visna Virus dUTPase Is Dispensable for Neuropathogenicity

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

A novel class of small molecule inhibitors targeting the chikungunya virus capping machinery with a high barrier to resistance

HIV-1-Associated Uracil DNA Glycosylase Activity Controls dUTP Misincorporation in Viral DNA and Is Essential to the HIV-1 Life Cycle

A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction

Toscana virus cap-snatching and initiation of transcription

Novel 2-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,3,4-oxadiazole and 3-phenyl-5-[(E)-2-(thiophen-2-yl)ethenyl]-1,2,4-oxadiazole derivatives as dengue virus inhibitors targeting NS5 polymerase

Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor

Functionalized 2,1-benzothiazine 2,2-dioxides as new inhibitors of Dengue NS5 RNA-dependent RNA polymerase

Broad spectrum anti-flavivirus pyridobenzothiazolones leading to less infective virions

Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1

Identification of [1,2,3]Triazolo[4,5‑d]pyrimidin-7(6H)‑ones as Novel Inhibitors of Chikungunya Virus Replication

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