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Small Molecule Protein-Protein Interaction Inhibitors as CNS Therapeutic Agents: Current Progress and Future Hurdles

Neuropsychopharmacology (New York, N.Y.), 2009-01, Vol.34 (1), p.126-141

2009

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Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Terminal Alkynes

Synthesis (Stuttgart), 2023-05, Vol.55 (22), p.3759-3776

2023

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Affinity informs environmental cooperation between ammonia-oxidizing archaea (AOA) and anaerobic ammonia-oxidizing (Anammox) bacteria

The ISME Journal, 2019-08, Vol.13 (8), p.1997-2004

2019

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A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

EMBO molecular medicine, 2021-07, Vol.13 (7), p.e13977-n/a

2021

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Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification

Development (Cambridge), 2024-03, Vol.151 (5)

2024

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Antigen‐binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones

Protein science, 2024-07, Vol.33 (7), p.e5081-n/a

2024

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Kinematic Investigation of Healthy, Arthritic, and Postsurgery Thumbs: Is the Metacarpophalangeal Joint the Gateway to Carpometacarpal Arthritis?

Journal of biomechanical engineering, 2024-07, Vol.146 (7)

2024

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Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models

Oncoimmunology, 2019-02, Vol.8 (2), p.e1539613-e1539613

2019

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Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids

Cell reports (Cambridge), 2023-11, Vol.42 (11), p.113354-113354, Article 113354

2023

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A Descriptor Set for Quantitative Structure‐property Relationship Prediction in Biologics

Molecular informatics, 2022-09, Vol.41 (9), p.e2100240-n/a

2022

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A phage‐displayed single‐chain Fab library optimized for rapid production of single‐chain IgGs

Protein science, 2020-10, Vol.29 (10), p.2075-2084

2020

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Engineered antigen‐binding fragments for enhanced crystallization of antibody:antigen complexes

Protein science, 2024-01, Vol.33 (1), p.e4824-n/a

2024

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Regulators of G Protein Signaling Proteins as Targets for Drug Discovery

Membrane Proteins As Drug Targets, 2010, Vol.91, p.81-119

2010

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Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

Cell reports. Medicine, 2022-10, Vol.3 (10), p.100754, Article 100754

2022

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A T cell redirection platform for co-targeting dual antigens on solid tumors

mAbs, 2021-01, Vol.13 (1), p.1933690-1933690

2021

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Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling

eLife, 2024-05, Vol.13

2024

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A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties

mAbs, 2018-11, Vol.10 (8), p.1157-1167

2018

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Intra-tourism trade, income distribution and tourism endowment: an econometric investigation

Applied economics, 2015-05, Vol.47 (21), p.2184-2200

2015

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PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

The Journal of biological chemistry, 2016-06, Vol.291 (26), p.13509-13519

2016

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Computed Tomography Evidence of Psoas Muscle Atrophy Without Concomitant Tendon Wasting in Early Sepsis

The Journal of surgical research, 2019-02, Vol.234, p.210-216

2019

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A Nanomolar-Potency Small Molecule Inhibitor of Regulator of G-Protein Signaling Proteins

Biochemistry (Easton), 2011-04, Vol.50 (15), p.3181-3192

2011

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Effects of the prebiotic mannan oligosaccharide on the experimental periodontitis in rats

Journal of clinical periodontology, 2018-09, Vol.45 (9), p.1078-1089

2018

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Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins

Molecular pharmacology, 2010-09, Vol.78 (3), p.524-533

2010

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Predicting mortality of elderly patients acutely admitted to the Department of Internal Medicine

International journal of clinical practice (Esher), 2015-04, Vol.69 (4), p.501-508

2015

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Liver macrophages regulate systemic metabolism through non-inflammatory factors

Nature metabolism, 2019-04, Vol.1 (4), p.445-459

2019

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Small Molecule Protein-Protein Interaction Inhibitors as CNS Therapeutic Agents: Current Progress and Future Hurdles

Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Terminal Alkynes

Affinity informs environmental cooperation between ammonia-oxidizing archaea (AOA) and anaerobic ammonia-oxidizing (Anammox) bacteria

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification

Antigen‐binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones

Kinematic Investigation of Healthy, Arthritic, and Postsurgery Thumbs: Is the Metacarpophalangeal Joint the Gateway to Carpometacarpal Arthritis?

Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models

Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids

A Descriptor Set for Quantitative Structure‐property Relationship Prediction in Biologics

A phage‐displayed single‐chain Fab library optimized for rapid production of single‐chain IgGs

Engineered antigen‐binding fragments for enhanced crystallization of antibody:antigen complexes

Regulators of G Protein Signaling Proteins as Targets for Drug Discovery

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b

A T cell redirection platform for co-targeting dual antigens on solid tumors

Structure and function of the ROR2 cysteine-rich domain in vertebrate noncanonical WNT5A signaling

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties

Intra-tourism trade, income distribution and tourism endowment: an econometric investigation

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

Computed Tomography Evidence of Psoas Muscle Atrophy Without Concomitant Tendon Wasting in Early Sepsis

A Nanomolar-Potency Small Molecule Inhibitor of Regulator of G-Protein Signaling Proteins

Effects of the prebiotic mannan oligosaccharide on the experimental periodontitis in rats

Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins

Predicting mortality of elderly patients acutely admitted to the Department of Internal Medicine

Liver macrophages regulate systemic metabolism through non-inflammatory factors

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