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6'- O -Lactose Ester Surfactants as an Innovative Opportunity in the Pharmaceutical Field: From Synthetic Methods to Biological Applications

Pharmaceuticals (Basel, Switzerland), 2021-12, Vol.14 (12), p.1306

2021

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The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer

Pharmaceuticals (Basel, Switzerland), 2022-09, Vol.15 (10), p.1166

2022

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Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20966-20971

2009

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Characterization of URB Series Synthetic Cannabinoids by HRMS and UHPLC-MS/MS

Pharmaceuticals (Basel, Switzerland), 2023-01, Vol.16 (2), p.201

2023

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Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.352-358

2005

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Synthetic Methodologies and Therapeutic Potential of Indole-3-Carbinol (I3C) and Its Derivatives

Pharmaceuticals (Basel, Switzerland), 2023-02, Vol.16 (2), p.240

2023

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Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models

Pain (Amsterdam), 2013-03, Vol.154 (3), p.350-360

2013

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Modulation of anxiety through blockade of anandamide hydrolysis

Nature medicine, 2003-01, Vol.9 (1), p.76-81

2003

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Inhibition of Fatty Acid Amide Hydrolase (FAAH) Regulates NF-kb Pathways Reducing Bleomycin-Induced Chronic Lung Inflammation and Pulmonary Fibrosis

International journal of molecular sciences, 2023-06, Vol.24 (12), p.10125

2023

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Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury

International journal of molecular sciences, 2022-03, Vol.23 (5), p.2781

2022

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α-Acylamino-β-lactone N -Acylethanolamine-hydrolyzing Acid Amidase Inhibitors Encapsulated in PLGA Nanoparticles: Improvement of the Physical Stability and Protection of Human Cells from Hydrogen Peroxide-Induced Oxidative Stress

Antioxidants, 2022-03, Vol.11 (4), p.686

2022

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Synthesis and Biological Evaluation of 6- O -Sucrose Monoester Glycolipids as Possible New Antifungal Agents

Pharmaceuticals (Basel, Switzerland), 2023-01, Vol.16 (2), p.136

2023

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Endocannabinoids in the treatment of mood disorders: evidence from animal models

Current pharmaceutical design, 2009-05, Vol.15 (14), p.1623-1646

2009

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Cyclohexylcarbamic Acid 3‘- or 4‘-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling Studies

Journal of medicinal chemistry, 2004-10, Vol.47 (21), p.4998-5008

2004

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Total Synthesis of Natural Disaccharide Sambubiose

Pharmaceuticals (Basel, Switzerland), 2020-08, Vol.13 (8), p.198

2020

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Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6917-6934

2013

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The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice

The Journal of pharmacology and experimental therapeutics, 2007-07, Vol.322 (1), p.236-242

2007

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Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition

PloS one, 2011-11, Vol.6 (11), p.e28142

2011

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Characterization and Preliminary In Vitro Antioxidant Activity of a New Multidrug Formulation Based on the Co-Encapsulation of Rutin and the α-Acylamino-β-Lactone NAAA Inhibitor URB894 within PLGA Nanoparticles

Antioxidants, 2023-01, Vol.12 (2), p.305

2023

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Synthesis and Biological Characterization of the New Glycolipid Lactose Undecylenate (URB1418)

Pharmaceuticals (Basel, Switzerland), 2022-04, Vol.15 (4), p.456

2022

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Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines

PloS one, 2012-08, Vol.7 (8), p.e43249-e43249

2012

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Synthesis and Properties of Sucrose- and Lactose-Based Aromatic Ester Surfactants as Potential Drugs Permeability Enhancers

Pharmaceuticals (Basel, Switzerland), 2023-02, Vol.16 (2), p.223

2023

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Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Nature neuroscience, 2005-09, Vol.8 (9), p.1139-1141

2005

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Synthesis and Structure−Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5770-5781

2010

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The Endocannabinoid System as a Target for Neuroprotection/Neuroregeneration in Perinatal Hypoxic-Ischemic Brain Injury

Biomedicines, 2022-12, Vol.11 (1), p.28

2022

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6'- O -Lactose Ester Surfactants as an Innovative Opportunity in the Pharmaceutical Field: From Synthetic Methods to Biological Applications

The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation

Characterization of URB Series Synthetic Cannabinoids by HRMS and UHPLC-MS/MS

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation

Synthetic Methodologies and Therapeutic Potential of Indole-3-Carbinol (I3C) and Its Derivatives

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models

Modulation of anxiety through blockade of anandamide hydrolysis

Inhibition of Fatty Acid Amide Hydrolase (FAAH) Regulates NF-kb Pathways Reducing Bleomycin-Induced Chronic Lung Inflammation and Pulmonary Fibrosis

Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury

α-Acylamino-β-lactone N -Acylethanolamine-hydrolyzing Acid Amidase Inhibitors Encapsulated in PLGA Nanoparticles: Improvement of the Physical Stability and Protection of Human Cells from Hydrogen Peroxide-Induced Oxidative Stress

Synthesis and Biological Evaluation of 6- O -Sucrose Monoester Glycolipids as Possible New Antifungal Agents

Endocannabinoids in the treatment of mood disorders: evidence from animal models

Cyclohexylcarbamic Acid 3‘- or 4‘-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling Studies

Total Synthesis of Natural Disaccharide Sambubiose

Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice

Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition

Characterization and Preliminary In Vitro Antioxidant Activity of a New Multidrug Formulation Based on the Co-Encapsulation of Rutin and the α-Acylamino-β-Lactone NAAA Inhibitor URB894 within PLGA Nanoparticles

Synthesis and Biological Characterization of the New Glycolipid Lactose Undecylenate (URB1418)

Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines

Synthesis and Properties of Sucrose- and Lactose-Based Aromatic Ester Surfactants as Potential Drugs Permeability Enhancers

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Synthesis and Structure−Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

The Endocannabinoid System as a Target for Neuroprotection/Neuroregeneration in Perinatal Hypoxic-Ischemic Brain Injury

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