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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell

PLoS pathogens, 2022-02, Vol.18 (2), p.e1009977-e1009977

2022

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PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum

PLoS pathogens, 2023-07, Vol.19 (7), p.e1011006-e1011006

2023

Volltextzugriff (PDF)

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

FEMS microbiology reviews, 2019-05, Vol.43 (3), p.223-238

2019

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Biosynthesis, Localization, and Macromolecular Arrangement of the Plasmodium falciparum Translocon of Exported Proteins (PTEX)

The Journal of biological chemistry, 2012-03, Vol.287 (11), p.7871-7884

2012

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Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

eLife, 2017-03, Vol.6

2017

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Plasmodium falciparum transfected with ultra bright NanoLuc luciferase offers high sensitivity detection for the screening of growth and cellular trafficking inhibitors

PloS one, 2014-11, Vol.9 (11), p.e112571-e112571

2014

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Functional Conservation of the AMA1 Host-Cell Invasion Ligand Between P. falciparum and P. vivax: A Novel Platform to Accelerate Vaccine and Drug Development

The Journal of infectious diseases, 2018-01, Vol.217 (3), p.498-507

2018

Volltextzugriff (PDF)

Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum

PloS one, 2012-07, Vol.7 (7), p.e40981-e40981

2012

Volltextzugriff (PDF)

Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development

Biochemical journal, 2013-06, Vol.452 (3), p.433-441

2013

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Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41

PloS one, 2012-07, Vol.7 (7), p.e41937-e41937

2012

Volltextzugriff (PDF)

Dissecting EXP2 sequence requirements for protein export in malaria parasites

Frontiers in cellular and infection microbiology, 2023, Vol.13, p.1332146-1332146

2023

Volltextzugriff (PDF)

Bottoms up! Malaria parasite invasion the right way around

Trends in parasitology, 2023-12, Vol.39 (12), p.1004-1013

2023

Volltextzugriff (PDF)

Plasmodium species: master renovators of their host cells

Nature reviews. Microbiology, 2016-08, Vol.14 (8), p.494-507

2016

Volltextzugriff (PDF)

Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon

BMC biology, 2011-03, Vol.9 (1), p.21-21, Article 21

2011

Volltextzugriff (PDF)

Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion

European journal of medicinal chemistry, 2021-03, Vol.214, p.113253, Article 113253

2021

Volltextzugriff (PDF)

Sequence elements within the PEXEL motif and its downstream region modulate PTEX‐dependent protein export in Plasmodium falciparum

Traffic (Copenhagen, Denmark), 2024-01, Vol.25 (1), p.e12922-n/a

2024

Volltextzugriff (PDF)

Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein

European journal of medicinal chemistry, 2024-04, Vol.270, p.116354-116354, Article 116354

2024

Volltextzugriff (PDF)

Plasmodium falciparum‐encoded exported hsp70/hsp40 chaperone/co‐chaperone complexes within the host erythrocyte

Cellular microbiology, 2012-11, Vol.14 (11), p.1784-1795

2012

Volltextzugriff (PDF)

The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host–parasite interface

The FEBS journal, 2018-06, Vol.285 (11), p.2037-2055

2018

Volltextzugriff (PDF)

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

BMC biology, 2015-07, Vol.13 (1), p.52-52, Article 52

2015

Volltextzugriff (PDF)

Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit

The Journal of biological chemistry, 2016-12, Vol.291 (49), p.25375-25386

2016

Volltextzugriff (PDF)

Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity

Bioorganic chemistry, 2021-12, Vol.117, p.105359-105359, Article 105359

2021

Volltextzugriff (PDF)

Recent insights into the export of PEXEL/HTS-motif containing proteins in Plasmodium parasites

Current opinion in microbiology, 2012-12, Vol.15 (6), p.699-704

2012

Volltextzugriff (PDF)

Molecular genetic tools in Toxoplasma and Plasmodium : achievements and future needs

Current opinion in microbiology, 2007-08, Vol.10 (4), p.349-356

2007

Volltextzugriff (PDF)

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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell

PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

Biosynthesis, Localization, and Macromolecular Arrangement of the Plasmodium falciparum Translocon of Exported Proteins (PTEX)

Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

Plasmodium falciparum transfected with ultra bright NanoLuc luciferase offers high sensitivity detection for the screening of growth and cellular trafficking inhibitors

Functional Conservation of the AMA1 Host-Cell Invasion Ligand Between P. falciparum and P. vivax: A Novel Platform to Accelerate Vaccine and Drug Development

Systematic analysis of FKBP inducible degradation domain tagging strategies for the human malaria parasite Plasmodium falciparum

Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development

Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41

Dissecting EXP2 sequence requirements for protein export in malaria parasites

Bottoms up! Malaria parasite invasion the right way around

Plasmodium species: master renovators of their host cells

Toward forward genetic screens in malaria-causing parasites using the piggyBac transposon

Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion

Sequence elements within the PEXEL motif and its downstream region modulate PTEX‐dependent protein export in Plasmodium falciparum

Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein

Plasmodium falciparum‐encoded exported hsp70/hsp40 chaperone/co‐chaperone complexes within the host erythrocyte

The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host–parasite interface

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

Development of a Novel CD4 + TCR Transgenic Line That Reveals a Dominant Role for CD8 + Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit

Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity

Recent insights into the export of PEXEL/HTS-motif containing proteins in Plasmodium parasites

Molecular genetic tools in Toxoplasma and Plasmodium : achievements and future needs

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