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Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules

Anti-cancer agents in medicinal chemistry, 2012-11, Vol.12 (9), p.1143-1155

2012

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Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.462-481

2018

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Indole: A privileged scaffold for the design of anti-cancer agents

European journal of medicinal chemistry, 2019-12, Vol.183, p.111691-111691, Article 111691

2019

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Synthesis of 1-Substituted 3-Aryl-5-aryl(hetaryl)-2-pyrazolines and Study of Their Antitumor Activity

Archiv der Pharmazie (Weinheim), 2012-04, Vol.345 (4), p.275-286

2012

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Traditional Chinese medicine (TCM) as a source of new anticancer drugs

Natural product reports, 2021-09, Vol.38 (9), p.1618-1633

2021

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Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation

European journal of medicinal chemistry, 2021-12, Vol.226, p.113837-113837, Article 113837

2021

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Anticancer property of ginsenoside Rh2 from ginseng

European journal of medicinal chemistry, 2020-10, Vol.203, p.112627-112627, Article 112627

2020

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Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1420-1442

2019

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Discovery of Novel Pyrrolo[2,3‑d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors

Journal of medicinal chemistry, 2022-01, Vol.65 (2), p.1243-1264

2022

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Review on Epidermal Growth Factor Receptor (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR Inhibitors

Current topics in medicinal chemistry, 2020-01, Vol.20 (10), p.815-834

2020

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Current developments of coumarin-based anti-cancer agents in medicinal chemistry

European journal of medicinal chemistry, 2015-09, Vol.102, p.611-630

2015

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New insights in Au-NHCs complexes as anticancer agents

European journal of medicinal chemistry, 2018-02, Vol.146, p.709-746

2018

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Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

European journal of medicinal chemistry, 2018-02, Vol.145, p.35-40

2018

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Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

European journal of medicinal chemistry, 2015-08, Vol.101, p.476-495

2015

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Biological potential of carbazole derivatives

European journal of medicinal chemistry, 2015-04, Vol.94, p.405-426

Głuszyńska, Agata

2015

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Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

European journal of medicinal chemistry, 2018-01, Vol.144, p.874-886

2018

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Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands

Journal of medicinal chemistry, 2018-01, Vol.61 (2), p.543-575

2018

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Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

European journal of medicinal chemistry, 2014-04, Vol.77, p.422-487

2014

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Synthesis and Bioevaluation of Diphyllin Glycosides as Novel Anticancer Agents

Archiv der Pharmazie (Weinheim), 2012-08, Vol.345 (8), p.622-628

2012

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Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c‑MYC Transcription Inhibitor Specifically Targeting the Promoter G‑Quadruplex

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2447-2459

2018

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Discovery of SHP2-D26 as a First, Potent, and Effective PROTAC Degrader of SHP2 Protein

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7510-7528

2020

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Organometallic Gold(III) Complexes Similar to Tetrahydroisoquinoline Induce ER-Stress-Mediated Apoptosis and Pro-Death Autophagy in A549 Cancer Cells

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3478-3490

2018

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Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4948-4964

2016

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An Update on Poly(ADP-ribose)polymerase‑1 (PARP-1) Inhibitors: Opportunities and Challenges in Cancer Therapy

Journal of medicinal chemistry, 2016-11, Vol.59 (21), p.9575-9598

2016

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Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

Journal of medicinal chemistry, 2011-09, Vol.54 (18), p.6342-6363

2011

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Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Indole: A privileged scaffold for the design of anti-cancer agents

Synthesis of 1-Substituted 3-Aryl-5-aryl(hetaryl)-2-pyrazolines and Study of Their Antitumor Activity

Traditional Chinese medicine (TCM) as a source of new anticancer drugs

Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation

Anticancer property of ginsenoside Rh2 from ginseng

Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)

Discovery of Novel Pyrrolo[2,3‑d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors

Review on Epidermal Growth Factor Receptor (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR Inhibitors

Current developments of coumarin-based anti-cancer agents in medicinal chemistry

New insights in Au-NHCs complexes as anticancer agents

Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

Biological potential of carbazole derivatives

Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands

Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

Synthesis and Bioevaluation of Diphyllin Glycosides as Novel Anticancer Agents

Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c‑MYC Transcription Inhibitor Specifically Targeting the Promoter G‑Quadruplex

Discovery of SHP2-D26 as a First, Potent, and Effective PROTAC Degrader of SHP2 Protein

Organometallic Gold(III) Complexes Similar to Tetrahydroisoquinoline Induce ER-Stress-Mediated Apoptosis and Pro-Death Autophagy in A549 Cancer Cells

Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase

An Update on Poly(ADP-ribose)polymerase‑1 (PARP-1) Inhibitors: Opportunities and Challenges in Cancer Therapy

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

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