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Novel drugs affecting diabetic peripheral neuropathy

Iranian journal of basic medical sciences, 2024-01, Vol.27 (6), p.657-670

2024

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Ginkgo biloba extract (EGb 761) mitigates methotrexate-induced testicular insult in rats: Targeting oxidative stress, energy deficit and spermatogenesis

Biomedicine & pharmacotherapy, 2021-11, Vol.143, p.112201, Article 112201

2021

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Eugenol alleviates acrylamide-induced rat testicular toxicity by modulating AMPK/p-AKT/mTOR signaling pathway and blood–testis barrier remodeling

Scientific reports, 2024-01, Vol.14 (1), p.1910-1910, Article 1910

2024

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Heamatococcus pluvialis ameliorates bone loss in experimentally-induced osteoporosis in rats via the regulation of OPG/RANKL pathway

Biomedicine & pharmacotherapy, 2019-08, Vol.116, p.109017-109017, Article 109017

2019

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Rosuvastatin and simvastatin attenuate cisplatin-induced cardiotoxicity via disruption of endoplasmic reticulum stress-mediated apoptotic death in rats: targeting ER-Chaperone GRP78 and Calpain-1 pathways

Toxicology reports, 2020-01, Vol.7, p.1178-1186

2020

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Doxorubicin-induced hepatic toxicity in rats: Mechanistic protective role of Omega-3 fatty acids through Nrf2/HO-1 activation and PI3K/Akt/GSK-3β axis modulation

Saudi journal of biological sciences, 2022-07, Vol.29 (7), p.103308-103308, Article 103308

2022

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Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

Molecules (Basel, Switzerland), 2017-10, Vol.22 (11), p.1820

2017

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Protective and therapeutic potentials of Dunaliella salina on aging-associated cardiac dysfunction in rats

Asian Pacific journal of tropical biomedicine, 2018-08, Vol.8 (8), p.403-410

2018

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Melatonin suppresses the brain injury after cerebral ischemia/reperfusion in hyperglycaemic rats

Research in pharmaceutical sciences, 2020-09, Vol.15 (5), p.418-428

2020

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Impact of type III collagen on monosodium iodoacetate-induced osteoarthritis in rats

Heliyon, 2020-06, Vol.6 (6), p.e04083-e04083, Article e04083

2020

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Chloroquine ameliorates bone loss induced by d-galactose in male rats via inhibition of ERK associated osteoclastogenesis and antioxidant effect

Toxicology reports, 2021-01, Vol.8, p.366-375

2021

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Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway

European journal of pharmacology, 2019-07, Vol.855, p.40-49

2019

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Dunalialla salina microalgea and its isolated zeaxanthin mitigate age-related dementia in rats: Modulation of neurotransmission and amyloid-β protein

Toxicology reports, 2021-01, Vol.8, p.1899-1908

2021

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Ovario-protective effects of genistein against cyclophosphamide toxicity in rats: Role of anti-müllerian hormone and oestradiol

European journal of pharmacology, 2016-10, Vol.789, p.163-171

2016

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Attenuation of Age-Related Hepatic Steatosis by Dunaliella salina Microalgae in Senescence Rats through the Regulation of Redox Status, Inflammatory Indices, and Apoptotic Biomarkers

Advances in pharmacological and pharmaceutical sciences, 2020, Vol.2020 (2020), p.1-11

2020

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Regioselective synthesis and molecular modeling study of vasorelaxant active 7,9-dioxa-1,2-diaza-spiro[4.5]dec-2-ene-6,10-diones

European journal of medicinal chemistry, 2010-09, Vol.45 (9), p.4229-4238

2010

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Synthesis, 3D-pharmacophore modelling and 2D-QSAR study of new pyridine-3-carbonitriles as vasorelaxant active agents

New journal of chemistry, 2021-05, Vol.45 (17), p.7731-774

2021

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Role of olmesartan in ameliorating diabetic nephropathy in rats by targeting the AGE/PKC, TLR4/P38-MAPK and SIRT-1 autophagic signaling pathways

European journal of pharmacology, 2022-08, Vol.928, p.175117-175117, Article 175117

2022

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Metabolome classification of Tongkat Ali (Eurycoma longifolia Jack) and its Commercial Products via UHPLC-QTOF-MS-MS and its protective effect against 5-Flurouracil-Induced Testicular Toxicity in Male rats

Journal of ethnopharmacology, 2024-10, p.118904, Article 118904

2024

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Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives

European journal of medicinal chemistry, 2016-01, Vol.108, p.663-673

2016

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HPLC-DAD-MS/MS profiling of phenolics from Securigera securidaca flowers and its anti-hyperglycemic and anti-hyperlipidemic activities

Revista brasileira de farmacognosia, 2015-03, Vol.25 (2), p.134-141

2015

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Metabolomic profiling of five Agave leaf taxa via UHPLC/PDA/ESI-MS inrelation to their anti-inflammatory, immunomodulatory and ulceroprotective activities

Steroids, 2020-08, Vol.160, p.108648, Article 108648

2020

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Uro-protective role of chrysin against cyclophosphamide-induced hemorrhagic cystitis in rats involving the turning-off NF-κB/P38-MAPK, NO/PARP-1 and STAT-3 signaling cascades

Chemico-biological interactions, 2023-09, Vol.382, p.110585-110585, Article 110585

2023

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Synergistic effect of aminoguanidine and l-carnosine against thioacetamide-induced hepatic encephalopathy in rats: behavioral, biochemical, and ultrastructural evidence

Canadian journal of physiology and pharmacology, 2021-03, Vol.99 (3), p.332-347

2021

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UPLC/QTOF/MS profiling of two Psidium species and the in-vivo hepatoprotective activity of their nano-formulated liposomes

Food research international, 2018-03, Vol.105, p.1029-1038

2018

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Novel drugs affecting diabetic peripheral neuropathy

Ginkgo biloba extract (EGb 761) mitigates methotrexate-induced testicular insult in rats: Targeting oxidative stress, energy deficit and spermatogenesis

Eugenol alleviates acrylamide-induced rat testicular toxicity by modulating AMPK/p-AKT/mTOR signaling pathway and blood–testis barrier remodeling

Heamatococcus pluvialis ameliorates bone loss in experimentally-induced osteoporosis in rats via the regulation of OPG/RANKL pathway

Rosuvastatin and simvastatin attenuate cisplatin-induced cardiotoxicity via disruption of endoplasmic reticulum stress-mediated apoptotic death in rats: targeting ER-Chaperone GRP78 and Calpain-1 pathways

Doxorubicin-induced hepatic toxicity in rats: Mechanistic protective role of Omega-3 fatty acids through Nrf2/HO-1 activation and PI3K/Akt/GSK-3β axis modulation

Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

Protective and therapeutic potentials of Dunaliella salina on aging-associated cardiac dysfunction in rats

Melatonin suppresses the brain injury after cerebral ischemia/reperfusion in hyperglycaemic rats

Impact of type III collagen on monosodium iodoacetate-induced osteoarthritis in rats

Chloroquine ameliorates bone loss induced by d-galactose in male rats via inhibition of ERK associated osteoclastogenesis and antioxidant effect

Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway

Dunalialla salina microalgea and its isolated zeaxanthin mitigate age-related dementia in rats: Modulation of neurotransmission and amyloid-β protein

Ovario-protective effects of genistein against cyclophosphamide toxicity in rats: Role of anti-müllerian hormone and oestradiol

Attenuation of Age-Related Hepatic Steatosis by Dunaliella salina Microalgae in Senescence Rats through the Regulation of Redox Status, Inflammatory Indices, and Apoptotic Biomarkers

Regioselective synthesis and molecular modeling study of vasorelaxant active 7,9-dioxa-1,2-diaza-spiro[4.5]dec-2-ene-6,10-diones

Synthesis, 3D-pharmacophore modelling and 2D-QSAR study of new pyridine-3-carbonitriles as vasorelaxant active agents

Role of olmesartan in ameliorating diabetic nephropathy in rats by targeting the AGE/PKC, TLR4/P38-MAPK and SIRT-1 autophagic signaling pathways

Metabolome classification of Tongkat Ali (Eurycoma longifolia Jack) and its Commercial Products via UHPLC-QTOF-MS-MS and its protective effect against 5-Flurouracil-Induced Testicular Toxicity in Male rats

Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives

HPLC-DAD-MS/MS profiling of phenolics from Securigera securidaca flowers and its anti-hyperglycemic and anti-hyperlipidemic activities

Metabolomic profiling of five Agave leaf taxa via UHPLC/PDA/ESI-MS inrelation to their anti-inflammatory, immunomodulatory and ulceroprotective activities

Uro-protective role of chrysin against cyclophosphamide-induced hemorrhagic cystitis in rats involving the turning-off NF-κB/P38-MAPK, NO/PARP-1 and STAT-3 signaling cascades

Synergistic effect of aminoguanidine and l-carnosine against thioacetamide-induced hepatic encephalopathy in rats: behavioral, biochemical, and ultrastructural evidence

UPLC/QTOF/MS profiling of two Psidium species and the in-vivo hepatoprotective activity of their nano-formulated liposomes

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