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Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

Immunological reviews, 2011-01, Vol.239 (1), p.149-166

Graham, Barney S.

2011

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The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation

American journal of transplantation, 2024-06, Vol.24 (6), p.897-904

2024

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Inno4Vac Workshop Report Part 2: RSV‐Controlled Human Infection Model (CHIM) Strain Selection and Immune Assays for RSV CHIM Studies, November 2021, MHRA, UK

Influenza and other respiratory viruses, 2024-10, Vol.18 (10), p.e70013-n/a

2024

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Experimental animal model for analyzing immunobiological responses following vaccination with formalin-inactivated respiratory syncytial virus

Microbiology and immunology, 2016-04, Vol.60 (4), p.234-242

2016

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Respiratory syncytial virus infection influences tight junction integrity

Clinical and experimental immunology, 2017-12, Vol.190 (3), p.351-359

2017

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CD8 T Cells Inhibit Respiratory Syncytial Virus (RSV) Vaccine-Enhanced Disease

Journal of Immunology, 2007-10, Vol.179 (8), p.5415-5424

2007

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Airway microbiome, host immune response and recurrent wheezing in infants with severe respiratory syncytial virus bronchiolitis

Pediatric allergy and immunology, 2020-04, Vol.31 (3), p.281-289

2020

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Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

EMBO molecular medicine, 2014-11, Vol.6 (11), p.1436-1454

2014

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Interindividual immunogenic variants: Susceptibility to coronavirus, respiratory syncytial virus and influenza virus

Reviews in medical virology, 2021-11, Vol.31 (6), p.e2234-n/a

2021

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ER stress protein PERK promotes inappropriate innate immune responses and pathogenesis during RSV infection

Journal of leukocyte biology, 2022-02, Vol.111 (2), p.379-389

2022

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Maternal awareness, acceptability and willingness towards respiratory syncytial virus (RSV) vaccination during pregnancy in Ireland

Immunity, Inflammation and Disease, 2024-04, Vol.12 (4), p.e1257-n/a

2024

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Inhibition of STAT6 during vaccination with formalin‐inactivated RSV prevents induction of Th2‐cell‐biased airway disease

European journal of immunology, 2014-08, Vol.44 (8), p.2349-2359

2014

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IL‐4Rα on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection

Journal of leukocyte biology, 2017-07, Vol.102 (1), p.153-161

2017

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Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice

European journal of immunology, 2016-04, Vol.46 (4), p.874-884

2016

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A virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A provides protection against viral challenge without priming for enhanced disease in cotton rats

Influenza and other respiratory viruses, 2013-11, Vol.7 (6), p.1227-1236

2013

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IL‐33 Receptor (ST2) Signalling is Important for Regulation of Th2‐Mediated Airway Inflammation in a Murine Model of Acute Respiratory Syncytial Virus Infection

Scandinavian journal of immunology, 2015-06, Vol.81 (6), p.494-501

2015

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Cold‐adapted influenza‐vectored RSV vaccine protects BALB/c mice and cotton rats from RSV challenge

Journal of medical virology, 2024-07, Vol.96 (7), p.e29308-n/a

2024

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Respiratory syncytial virus infection and immunity

Reviews in medical virology, 2012-07, Vol.22 (4), p.230-244

2012

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IL‐17E (IL‐25) and IL‐17RB promote respiratory syncytial virus‐induced pulmonary disease

Journal of leukocyte biology, 2014-05, Vol.95 (5), p.809-815

2014

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Feasibility of Freeze-Drying Oil-in-Water Emulsion Adjuvants and Subunit Proteins to Enable Single-Vial Vaccine Drug Products

Journal of pharmaceutical sciences, 2017-06, Vol.106 (6), p.1490-1498

2017

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Impaired gamma delta T cell‐derived IL‐17A and inflammasome activation during early respiratory syncytial virus infection in infants

Immunology and cell biology, 2015-02, Vol.93 (2), p.126-135

2015

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IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates

Journal of leukocyte biology, 2013-06, Vol.93 (6), p.933-942

2013

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Deletion of TLR3 Alters the Pulmonary Immune Environment and Mucus Production during Respiratory Syncytial Virus Infection

Journal of Immunology, 2006-02, Vol.176 (3), p.1937-1942

2006

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Systematic Review of the Efficacy and Safety of RSV‐Specific Monoclonal Antibodies and Antivirals in Development

Reviews in medical virology, 2024-09, Vol.34 (5), p.e2576-n/a

2024

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Dual role of interleukin‐10 in the regulation of respiratory syncitial virus (RSV)‐induced lung inflammation

Clinical and experimental immunology, 2013-05, Vol.172 (2), p.263-279

2013

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Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation

Inno4Vac Workshop Report Part 2: RSV‐Controlled Human Infection Model (CHIM) Strain Selection and Immune Assays for RSV CHIM Studies, November 2021, MHRA, UK

Experimental animal model for analyzing immunobiological responses following vaccination with formalin-inactivated respiratory syncytial virus

Respiratory syncytial virus infection influences tight junction integrity

CD8 T Cells Inhibit Respiratory Syncytial Virus (RSV) Vaccine-Enhanced Disease

Airway microbiome, host immune response and recurrent wheezing in infants with severe respiratory syncytial virus bronchiolitis

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

Interindividual immunogenic variants: Susceptibility to coronavirus, respiratory syncytial virus and influenza virus

ER stress protein PERK promotes inappropriate innate immune responses and pathogenesis during RSV infection

Maternal awareness, acceptability and willingness towards respiratory syncytial virus (RSV) vaccination during pregnancy in Ireland

Inhibition of STAT6 during vaccination with formalin‐inactivated RSV prevents induction of Th2‐cell‐biased airway disease

IL‐4Rα on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection

Flt3 ligand improves the innate response to respiratory syncytial virus and limits lung disease upon RSV reexposure in neonate mice

A virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A provides protection against viral challenge without priming for enhanced disease in cotton rats

IL‐33 Receptor (ST2) Signalling is Important for Regulation of Th2‐Mediated Airway Inflammation in a Murine Model of Acute Respiratory Syncytial Virus Infection

Cold‐adapted influenza‐vectored RSV vaccine protects BALB/c mice and cotton rats from RSV challenge

Respiratory syncytial virus infection and immunity

IL‐17E (IL‐25) and IL‐17RB promote respiratory syncytial virus‐induced pulmonary disease

Feasibility of Freeze-Drying Oil-in-Water Emulsion Adjuvants and Subunit Proteins to Enable Single-Vial Vaccine Drug Products

Impaired gamma delta T cell‐derived IL‐17A and inflammasome activation during early respiratory syncytial virus infection in infants

IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates

Deletion of TLR3 Alters the Pulmonary Immune Environment and Mucus Production during Respiratory Syncytial Virus Infection

Systematic Review of the Efficacy and Safety of RSV‐Specific Monoclonal Antibodies and Antivirals in Development

Dual role of interleukin‐10 in the regulation of respiratory syncitial virus (RSV)‐induced lung inflammation

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